5-(2-Pyridyl) -1,2-Dihydropyridin-2-one CAS 381233-78-9 Perampanel Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 5-(2-Pyridyl) -1,2-Dihydropyridin-2-one ([2,3'-Bipyridin] -6'(1'H)-one) (CAS: 381233-78-9) e nang le boleng bo phahameng, bohareng ba Perampanel (CAS: 380917-97-5).Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka li-intermediate tsa Perampanel,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | 5-(2-Pyridyl) -1,2-Dihydropyridin-2-one |
| Litlhaloso tse tšoanang | [2,3'-Bipyridin] -6'(1'H) -nngwe;5-(Pyridin-2-yl)pyridin-2(1H)-nngwe;5-(Pyridin-2-yl)-2(1H)-Pyridone;5-(2-Pyridyl)pyridin-2(1H)-nngwe;5-Pyridin-2-yl-1H-Pyridin-2-one;5-(Pyridin-2-yl) -1,2-Dihydropyridin-2-one;Tšilafalo ea Perampanel 1 |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 381233-78-9 |
| Foromo ea limolek'hule | Setšoantšo sa C10H8N2O |
| Boima ba Molek'hule | 172.18 g/mol |
| Melting Point | 71.0 ~ 75.0℃ |
| Botenya | 1.221±0.06 g/cm3 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha | Bohareng ba Perampanel (CAS: 380917-97-5) |
| Shelf Life | Likhoeli tse 24 Haeba li Behiloe Hantle |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Phofo e Bosoeu ho isa ho e Batlileng e Tsweu | Phofo e Tshweu |
| Mokhoa oa Bohloeki / Analysis | >98.0% (HPLC) | 99.7% |
| Metsi ka Karl Fischer | <1.00% | 0.58% |
| Tšilafalo e le Mong | <1.00% | E lumellana |
| Litšila ka Kakaretso | <2.00% | 0.30% |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
| Kopo | Bohareng ba Perampanel (CAS: 380917-97-5) | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Thepa: Phofo e tšoeu ho isa ho e batlang e le tšoeu
Solvent: Tetrahydrofuran, Toluene, Ethylacetate, Ethanol, Methanol, tert-Butyl Methyl Ether, Petroleum Ether, n-Hexane, Dichloromethane
Sheba: Lintho Tse Amanang le Ena: Nka sehlahisoa sena 'me u se hlapolle ka diluent (metsi a mobile phase: methanol (50∶50)) ho etsa tharollo e nang le hoo e ka bang 0.5mg ka 1ml e le tharollo ea sehlahisoa sa teko.Ho latela ts'ebetso e phahameng ea chromatography ea mokelikeli (Chinese Pharmacopoeia 2010 Edition II Sehlomathiso Ⅴ D), gel ea silica (ZORBAX SB-C18 4.6×250mm,5m) e ne e sebelisoa e le setlatsi.Mohato oa A e ne e le metsi, karolo ea B ea mohala e ne e le methanol, 'me bolelele ba ho lemoha e ne e le 254nm.Sekhahla sa phallo e ne e le 1.0ml / min mme mocheso oa kholomo e ne e le mocheso oa kamore.5μl ea tharollo ea teko e ile ea lekanngoa ka nepo 'me ea kenngoa ka har'a chromatograph ea metsi ho hatisa chromatogram.Ho ea ka mokhoa oa ho tloaeleha sebakeng, litaba tsa sehlahisoa sena ha li ka tlase ho 98%.Haeba ho na le litlhoro tsa ho se hloeke ka har'a chromatogram ea tharollo ea sehlahisoa sa tlhahlobo, sebaka sa tlhoro ea litšila ha se na ho feta 1.0%, 'me kakaretso ea sebaka sa tlhoro ea litšila ha ea lokela ho feta 2.0%.
Mongobo: Nka sehlahisoa sena, sebelisa teko ea mongobo, ho latela mokhoa oa Karl Fischer (Chinese Pharmacopoeia 2010 khatiso ea II Sehlomathiso Ⅷ M mokhoa oa pele A) boikemisetso, mongobo o ke ke oa feta 1.0%.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
5-(2-Pyridyl) -1,2-Dihydropyridin-2-one ([2,3'-Bipyridin] -6'(1'H)-one) (CAS: 381233-78-9), bohareng ba Perampanel (CAS: 380917-97-5).Perampanel (e fuoe laesense ka 2012) ke AED ea moloko oa boraro e tsejoang ka lebitso la khoebo la Fycompa® (Eisai, Hatfield) UK le Banzel® (Eisai, Hatfield) naheng ea USA.Kalafo e tlatselletsang ea ho tsietsana ha lintho tse tsepameng kapa ntle le kakaretso ea bobeli le li-primary generalized tonic-clonic seizures.Ka Mphalane 2012, US FDA e ile ea amohela perampanel bakeng sa kalafo ea ho tsietsana ha karolo e itseng ho bakuli ba sethoathoa ba nang le bonyane lilemo tse 12.Perampanel ke mohanyetsi oa pele oa AMPA ho amohela tumello ea FDA joalo ka AED.Li-receptor tsa AMPA glutamate li fumanoa haholo-holo ho li-neuron tsa postsynaptic bokong.Joalo ka mohanyetsi ea khethiloeng, ea se nang tlholisano oa AMPA, parampanel e thibela ho buloa ha mocha oa ion le ho fokotsa ho ata ha bokhoni ba ketso.
