Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Purity >99.0% (HPLC)
Lebitso la Lik'hemik'hale | Lapatinib Ditosylate Monohydrate |
Litlhaloso tse tšoanang | N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine |
Nomoro ea CAS | 388082-78-8 |
Boemo ba Setoko | E teng thepeng e teng ka lebenkeleng |
Foromo ea limolek'hule | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Boima ba Molek'hule | 943.48 |
COA & MSDS | E fumaneha |
Tšimoloho | Shanghai, China |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e Bosehla ho ea ho e Tšehla |
Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
Melting Point | 240.0~242.0℃ |
Mongobo (KF) | 1.9~2.4% |
Tšilafalo e le Mong | ≤0.50% |
Litšila ka Kakaretso | ≤1.00% |
Heavy Metals (as Pb) | ≤20ppm |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API;Bakeng sa ho phekola bakuli ba nang le kankere ea matsoele |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) ke letsoai la ditosylate laCAS 231277-92-2, quinazoline ea maiketsetso, e sebetsang ka molomo e nang le ts'ebetso e ka bang teng ea antineoplastic.E thibela ka mokhoa o fetohang phosphorylation ea epidermal growth factor receptor (EGFR), ErbB2, le Erk-1 le-2 le AKT kinases;e boetse e thibela maemo a protheine ea cyclin D meleng ea lisele tsa tumor ea motho le xenografts.EGFR le ErbB2 li kentse letsoho kholong ea mefuta e fapaneng ea hlahala.E ile ea qalisoa bakeng sa phekolo ea kankere ea matsoele e tsoetseng pele kapa ea metastatic HER2 (ErbB2) ho basali ba fumaneng phekolo ea pele.Setlhare se ile sa sibolloa mme sa ntlafatsoa ke GlaxoSmithKline.