Apixaban Intermediate CAS 545445-44-1 Bohloeki >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445) -44-1) e nang le boleng bo phahameng, bohareng ba Apixaban (CAS: 503612-47-3).Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka li-Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one |
| Litlhaloso tse tšoanang | Apixaban Bohareng ba 1;5,6-Dihydro-3- (4-Morpholinyl) -1-[4-(2-Oxo-1-Piperidinyl) phenyl] -2 (1H) -Pyridinone;5-Morpholin-4-yl-1-[4-(2-Oxopiperidin-1-yl) phenyl] -2,3-Dihydropyridin-6-one;Apixaban Impurity A |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 545445-44-1 |
| Foromo ea limolek'hule | Setšoantšo sa C20H25N3O3 |
| Boima ba Molek'hule | 355.43 g/mol |
| Melting Point | >199℃(Dec.) |
| Botenya | 1.267 g/mL |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha | Bohareng ba Apixaban (CAS: 503612-47-3) |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo e Sehla e Khanyang | Phofo e Sehla e Khanyang |
| Tahlehelo ka ho Omisa | <0.50% | 0.16% |
| Masalla a ho Ignition | <0.20% | 0.07% |
| Mokhoa oa Bohloeki / Analysis | >98.0% (HPLC Area) | 99.12% |
| Tšilafalo efe kapa efe ea Motho ka Mong | <0.50% | <0.50% |
| Litšila ka Kakaretso | <2.00% | 0.88% |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| LC-MS bakeng sa Boitsebiso | E lumellana | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
| Kopo | Bohareng ba Apixaban (CAS: 503612-47-3) | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445-44-1) ke bohareng ba Apixaban (CAS: 503612-47-3).
Apixaban ke mofuta o mocha oa oral Xa factor inhibitor e kopantsoeng ke Bristol-Myers Squibb le Pfizer.Lebitso la khoebo ke Eratol, e leng mofuta o mocha oa anticoagulant ea molomo.Ka ho thibela ntho ea bohlokoa ea coagulation Xa, Apixaban e ka thibela tlhahiso ea thrombin le thrombosis.Ka la 26 April, 2007, Bristol-Myers Squibb o ile a ikopanya le Pfizer ho phatlalatsa tšebelisano-'moho ho nts'etsopele ea anticoagulant e ncha ea molomo Apixaban e nang le Bristol-Myers Squibb e le mokhoa o ntlafalitsoeng oa Warfarin.Ka May 2011, Apixaban e bile eena oa pele oa ho amohela thibelo ea venous thrombosis ho bakuli ba baholo ba etsoang opereishene e khethehileng ea letheka kapa lengole linaheng tsa 27 EU, Iceland le Norway.Ka la 20 November, 2012, Komisi ea Europe e ile ea amohela Ererto (Apixaban) bakeng sa thibelo ea lefu la stroke le systemic embolism ho bakuli ba baholo ba nang le non-valvular atrial fibrillation (NVAF) e nang le mabaka a le mong kapa a mangata a kotsi.Ka mor'a moo, Tsamaiso ea Lijo le Lithethefatsi ea Canada, Japane, le US FDA e amohetse Ererto (Apixaban) bakeng sa thibelo ea lefu la stroke le systemic embolism ho bakuli ba baholo ba nang le non-valvular atrial fibrillation (NVAF) e nang le kotsi e le 'ngoe kapa ho feta.Ka April 12, 2013, lithethefatsi tse ncha tsa anticoagulant Eloto (ELIQUIS) (Apixaban) tse kopantsoeng ke Bristol-Myers Squibb le Pfizer li phatlalalitsoe ka molao hore li thathamisitsoe Chaena.
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