5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Bohloeki bo Hare >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6) e nang le boleng bo phahameng, bohareng ba Apalutamide (CAS: 956104-40-8).Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka li-Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | 5-Amino-3-(Trifluoromethyl)picolinonitrile |
| Litlhaloso tse tšoanang | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile;5-Amino-3- (Trifluoromethyl) 2-Cyanopyridine;5-Amino-2-Cyano-3-(Trifluoromethyl)pyridine;Ho se hloeke ha Apalutamide 10 |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 573762-62-6 |
| Foromo ea limolek'hule | C7H4F3N3 |
| Boima ba Molek'hule | 187.12 g/mol |
| Botenya | 1.45±0.10 g/cm3 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha sa Likotsi | 6.1 |
| Sehlopha sa ho paka | Ⅲ |
| Sehlopha | Bohareng ba Apalutamide (CAS: 956104-40-8) |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Bosehla bo Khanyang ho ea ho Bosehla bo Tiileng | E lumellana |
| Metsi ka Karl Fischer | <0.50% | 0.35% |
| Mokhoa oa Bohloeki / Analysis | >98.0% (HPLC) | 99.03% |
| Infrared Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
| Kopo | Bohareng ba Apalutamide (CAS: 956104-40-8) | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6), ke pyridine heterocyclic organic compound, e ka sebelisoang e le li-intermediate tsa meriana.5-Amino-3- (Trifluoromethyl) picolinonitrile ke karolo e bohareng ea Apalutamide (CAS: 956104-40-8).Apalutamide ke antiandrogen ea moloko oa bobeli e sebelisoang ho phekola mofetše oa senya.Ke mohanyetsi ea matla oa li-androgen receptor tse nang le boleng ba IC50 ba 16 nM.E tlama li-receptor tsa androgen, ka hona e thibela phetisetso ea nyutlelie, ho tlama DNA le ts'ebetso ea transcriptal.Apalutamide e na le ts'ebeliso ea kalafo ho mofets'e oa tšoelesa ea senya e seng metastatic.
Apalutamide e sebelisetsoa ho alafa mefuta e itseng ea mofetše oa tšoelesa ea senya e hananang le ho haroa kapa mofetše oa tšoelesa ea senya e sa namelang likarolong tse ling tsa 'mele, empa e sa thusoe ke liphekolo tse ling tsa bongaka.Apalutamide e sehlopheng sa meriana e bitsoang androgen receptor inhibitors.E sebetsa ka ho thibela liphello tsa androgen ho thibela ho hōla le ho ata ha lisele tsa kankere.Ka la 17 Loetse 2019, Tsamaiso ea Lijo le Lithethefatsi e amohetse Apalutamide (ERLEADA, Janssen Biotech, Inc) bakeng sa bakuli ba nang le mofetše oa tšoelesa ea senya ea metastatic castration-sensitive (mCSPC).Apalutamide e ile ea amoheloa qalong ka selemo sa 2018 bakeng sa bakuli ba nang le mofetše oa tšoelesa ea senya o se nang metastatic castration.
