Trelagliptin Succinate Intermediate CAS 865759-24-6 Purity >98.0% (HPLC) Setšoantšo se Featured

Trelagliptin Succinate Intermediate CAS 865759-24-6 Bohloeki >98.0% (HPLC)

Tlhaloso e Khutšoanyane:

Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6

Bohloeki: >98.0% (HPLC)

Ponahalo: Bosoeu bo Bosoeu ho isa ho Crystal e Bosehla bo Khanyang

Bohareng ba Trelagliptin Succinate (CAS: 1029877-94-8) bakeng sa kalafo ea Mofuta oa 2 oa lefu la tsoekere

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Mekhatlo e Amanang le Phepelo ea Trelagliptin Succinate:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Trelagliptin Succinate Intermediate-int D
Litlhaloso tse tšoanang	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl) -4-fluorobenzonitrile;2- [(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
Ho se hloeke	Tšilafalo ea Trelagliptin 17
Boemo ba Setoko	Ho Stock, Commercial Scale
Nomoro ea CAS	865759-24-6
Foromo ea limolek'hule	C13H9ClFN3O2
Boima ba Molek'hule	293.68 g/mol
Botenya	1.49±0.10 g/cm3
Mocheso oa polokelo.	Sebaka se pholileng le se omileng
COA & MSDS	E fumaneha
Brand	Ruifu Chemical

Litlhaloso:

Lintho	Maemo a Tlhahlobo	Liphetho
Ponahalo	Crystal e Bosoeu ho ea ho Khanya e Bosehla	E lumellana
Boitsebiso
HPLC	Nako ea ho boloka sampole ea tlhoro e kholo e lumellana le maemo a litšupiso	E lumellana
IR - Infrared Spectrum	IR Absorption spectra ea sampole le standard lia lumellana	E lumellana
Tlhahlobo
Tahlehelo ka ho Omisa	<0.50%	0.3%
Litšila ka Kakaretso	<2.00%	E lumellana
Mokhoa oa Bohloeki / Analysis	>98.0% (HPLC)	99.1%
Qetello	Sehlahisoa se lekoa 'me se lumellana le litlhaloso

Sephutheloana/Bobolokelo/Ho tsamaisa ka sekepe:

Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.Qoba leseli;E sa keneleng moea.
Ho tsamaisa ka sekepe:Fana ka lefatše ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

Bokhoni bo lekaneng: Lisebelisoa le litsebi tse lekaneng

Tšebeletso ea profeshenale: Tšebeletso e le 'ngoe ea ho reka

Sephutheloana sa OEM: Sephutheloana sa tloaelo le leibole lia fumaneha

Tlhahiso e potlakileng: Haeba e le ka har'a setoko, ho netefalitsoe hore ho tsamaisoa matsatsi a mararo

Thepa e tsitsitseng: Boloka thepa e lekaneng

Tšehetso ea Theknoloji: Tharollo ea theknoloji e teng

Tšebeletso e Tloaelehileng ea ho Kopanya: Ho tloha ho ligrama ho isa ho lik'hilograma

Boleng bo Phahameng: Ho thehile tsamaiso e felletseng ea netefatso ea boleng

LBH:

Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.

Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.

Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.

BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.

Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.

Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.

MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.

Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.

Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.

Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.

Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.

Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.

Kopo:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) e sebelisoa e le bohareng ba Trelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, e hlahisitsoeng ke Takeda, Japane, e qalileng ka Hlakubele 2015, tlasa lebitso la khoebo la Zafatek, e sebelisoa ho phekola lefu la tsoekere la mofuta oa 2.Trelagliptin ke inhibitor ea nako e telele ea dipeptidyl peptidase IV (DPP-4) ka ho khetha le ho tsoela pele ho thibela DPP-4 ho laola maemo a tsoekere ea mali.Trelagliptin ke setlhare sa pele sa beke le beke sa hypoglycemic 'marakeng,' me li-inhibitors tse tšoanang tsa DPP-4 'marakeng li hloka ho nooa hang ka letsatsi.Melemo ea meriana ea Zafatek ntle le pelaelo e tla fana ka likhetho tse bonolo haholoanyane tsa kalafo bakeng sa bakuli ba lefu la tsoekere.Ho lebeletsoe ho ntlafatsa haholo boiketlo le ho latela melao ea bakuli.ka la 26 Hlakubele 2015, seqhenqha sa meriana sa Japane Takeda se phatlalalitse hore moriana o mocha oa lefu la tsoekere Zafatek o amohetsoe ke Lefapha la Bophelo, la Basebetsi le Boiketlo ba Japane (MHLW) bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2.Kamohelo e tšoaea Zafatek ho ba moriana oa pele oa beke le beke oa hypoglycemic 'marakeng lefatšeng, hape e emela blockbuster e theohileng ke Takeda' marakeng oa lefu la tsoekere.
Trelagliptin ke inhibitor ea dipeptidyl peptidase IV (DPP-4) ea hang ka beke e laolang boemo ba tsoekere ea mali ka ho khetha le ho tsoela pele ho thibela DPP-4.DPP-4 ke enzyme e ka qalang ts'ebetso ea incretin (glucagon-like peptide -1 (GLP-1) le insulinotropic polypeptide (GIP) e itšetlehileng ka tsoekere, e bapalang karolo ea bohlokoa taolong ea tsoekere ea mali.Thibelo ea DPP-4 e ka eketsa secretion ea insulin e itšetlehileng ka tsoekere ea mali, kahoo e laola boemo ba tsoekere ea mali.Tlhahiso ea Trelagliptin NDA e ipapisitse le lintlha tsa ts'ireletso le ts'ireletso ho tsoa litekong tse 'maloa tsa kliniki tsa Mokhahlelo oa III tse entsoeng ho bakuli ba Majapane ba nang le lefu la tsoekere la mofuta oa 2.Ho sebetsa ha Trelagliptin ho netefalitsoe litekong tsohle, 'me e na le polokeho e ntle le mamello.Tsamaiso ea Trelagliptin hang ka beke e ka laola boemo ba tsoekere ea mali ka nepo mme e lebelletsoe ho ntlafatsa ho latela melao ea meriana ea bakuli.