4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Bohloeki >98.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la Lik'hemik'hale: 4-Chloro-6-Iodoquinazoline

CAS: 98556-31-1

Bohloeki: >98.0% (HPLC)

Ponahalo: Lefats'e le Lesehla ho ea ho Phofo e Bosehla-Sootho

Bohareng ba Lapatinib / Lapatinib Ditosylate Monohydrate

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka 4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com

Lapatinib Intermediates:

Motheo oa Lapatinib	CAS 231277-92-2
Lapatinib Ditosylate Monohydrate	CAS 388082-78-8
Sodium methanesulfinate	CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	CAS 16064-08-7
5-Formyl-2-Furanboronic Acid	CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	CAS 231278-84-5

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	4-Chloro-6-Iodoquinazoline
Litlhaloso tse tšoanang	6-Iodo-4-Chloroquinazoline
Boemo ba Setoko	Ka Stock, Tlhahiso ea Khoebo
Nomoro ea CAS	98556-31-1
Foromo ea limolek'hule	C8H4ClIN2
Boima ba Molek'hule	290.49 g/mol
Melting Point	175.0 ho isa ho 179.0 ℃
Botenya	2.017±0.06 g/cm3
Refractive Index n20/D	1.739
E hloahloa	Ha A na Moeeng
COA & MSDS	E fumaneha
Tšimoloho	Shanghai, China
Brand	Ruifu Chemical

Litlhaloso:

Lintho	Maemo a Tlhahlobo	Liphetho
Ponahalo	Lefats'e Bosehla ho ea ho Bosehla-Sootho Phofo	Lefatše Phofo e Sehla
Melting Point	175.0 ho isa ho 179.0 ℃	177.2 ℃
Tahlehelo ka ho Omisa	<1.00%	0.15%
Mokhoa oa Bohloeki / Analysis	>98.0% (HPLC)	98.43%
1H NMR Spectrum	E tsamaellanang le Sebopeho	E lumellana
Qetello	Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng
Kopo	Bohareng ba Lapatinib / Lapatinib Ditosylate Monohydrate

Sephutheloana/Bobolokelo/Ho tsamaisa ka sekepe:

Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

Bokhoni bo lekaneng: Lisebelisoa le litsebi tse lekaneng

Tšebeletso ea profeshenale: Tšebeletso e le 'ngoe ea ho reka

Sephutheloana sa OEM: Sephutheloana sa tloaelo le leibole lia fumaneha

Tlhahiso e potlakileng: Haeba e le ka har'a setoko, ho netefalitsoe hore ho tsamaisoa matsatsi a mararo

Thepa e tsitsitseng: Boloka thepa e lekaneng

Tšehetso ea Theknoloji: Tharollo ea theknoloji e teng

Tšebeletso e Tloaelehileng ea ho Kopanya: Ho tloha ho ligrama ho isa ho lik'hilograma

Boleng bo Phahameng: Ho thehile tsamaiso e felletseng ea netefatso ea boleng

LBH:

Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.

98556-31-1 - Kopo:

4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) ke karolo e bohareng ea motsoako oa Lapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
Lapatinib ke sethethefatsi se secha sa kankere ea matsoele se lebisitsoeng ho phekolo e entsoeng le ho etsoa ke GlaxoSmithKline, e ileng ea amoheloa ke US Food and Drug Administration ka March 13, 2007. Pontšo e amohelehang hona joale e kopantsoe le capecitabine bakeng sa kankere ea matsoele e tsoetseng pele kapa ea metastatic, le bakuli ba kankere ea matsoele. e tlameha ho phekoloa ka meriana e meng ea pele.Lebitso la eona la khoebo United States ke Tykerb.Ka December 14, 2007, European Medicines Agency (EMEA) e amohetse lethathamo la Lapatinib Europe tlas'a lebitso la khoebo Tyverb.Phekolo e lebisitsoeng ho limolek'hule bakeng sa mofetše oa matsoele e bua ka kalafo ea li-oncogenes le lihlahisoa tse amanang le polelo tse amanang le ho hlaha le nts'etsopele ea mofetše oa matsoele.Lithethefatsi tse etselitsoeng limolek'hule li thibela kapa li bolaea lisele tsa hlahala ka ho thibela phetisetso ea lets'oao ho lisele tsa hlahala kapa lisele tse amanang le tsona ho laola liphetoho tsa polelo ea liphatsa tsa lefutso.Lapatinib ke molomo o monyenyane oa molek'hule oa epidermal growth factor tyrosine kinase inhibitor.Liteko tsa bongaka li bonts'itse hore ho bakuli ba mofets'e oa HER2 ba nang le khanyetso ho Roche's Herceptin (Herceptin), Lapatinib e na le phello e ntle ea bongaka.Liteko tsa in vitro, Lapatinib e bile le phello e kholo ea inhibitory ho mela ea lisele tsa mofetše oa matsoele oa Her-2.Litekong tsa Mokhahlelo oa Pele oa mofetše oa matsoele o tsoetseng pele ka Her-2 overexpression, Lapatinib e boetse e na le sekhahla se sebetsang hantle 'me ha e na khanyetso ea Herceptin (trastuzumab).Hobane sebopeho sa eona ke molek'hule e nyane, ho fapana le Herceptin (trastuzumab), e ka kenella mokoallong oa boko ba mali mme e na le phello e itseng ea kalafo ho metastasis ea boko ea mofetše oa matsoele.