α-Cyclodextrin (α-CD) CAS 10016-20-3 Excipients ea Pharmaceutical
Ruifu Chemical ke moetsi ea ka sehloohong oa α-Cyclodextrin (α-CD) (CAS: 10016-20-3) e nang le boleng bo phahameng.Ruifu Chemical e fana ka pharma grade cyclodextrins, li-excipients tsa meriana.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Reka α-Cyclodextrin,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | α-Cyclodextrin |
| Litlhaloso tse tšoanang | α-CD;C;Alfadex;alpha-Dextrin;α-Dextrin;Cyclohexapentylose;Cavamax W6;Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;Cyclomaltohexaose;Cyclohexaamylose |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 10016-20-3 |
| Foromo ea limolek'hule | C |
| Boima ba Molek'hule | g/mol |
| Melting Point | >278℃(Dec.) (lit.) |
| Ntlha e belang | ℃ |
| Flash point | ℃ |
| Botenya | |
| Refractive Index n20/D | 1 |
| E hloahloa | Hygroscopic.Ha e na Moeeng, Ha e Mamelle Leseli, Ha e na Mongobo |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing |
| Solubility | E qhibilihang ka hare |
| Botsitso | E tsitsitseng.E tukang.Ha e tsamaellane le li-agent tse matla tsa oxidizing. |
| COA & MSDS | E fumaneha |
| Mohlala oa mahala | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha | Excipients Meriana;Lisebelisoa tsa Lijo |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | E tšoeu kapa e batlile e tšoeu Amorphous kapa Crystalline Powder | E lumellana |
| Solubility | E qhibiliha ka Bolokolohi ka Metsing le ho Propylene Glycol, Ha e khone ho qhibiliha ka Ethanol le Methylene Chloride | E lumellana |
| ldentification HPLC | Nako ea ho boloka tlhōrō e kholo ea tharollo ea sampole e lumellana le tharollo e tloaelehileng. | E lumellana |
| Tharollo ea Tlhahlobo ea Iodine | Pula e Yellow-Brown e Thehile | E lumellana |
| Tlhahlobo | 98.0%~101.0% (E baloa ka Motheo o Omisitsoeng) | 100.0% |
| Phetoho e khethehileng [a]20/D | +147.0° ho ea ho +152.0°(C=1 ho H2O) (Calcd. ka Anh. Substance) | +148,2° |
| Ho hlaka le Mmala oa Tharollo | 10mg/ ml Tharollo ea Metsi e Hlakile ebile ha e na Mebala | E lumellana |
| Moeli oa Lintho tse Monyang Khanya | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | E lumellana |
| Boikemisetso ba Metsi | ≤11.0% | 9.9% |
| Masalla a ho Ignition | ≤0.10% | 0.07% |
| Litšepe tse boima | ≤5ppm | <5ppm |
| Letsoai la Arsenic (Joaloka) | ≤1.3ppm | <1.3ppm |
| Ho fokotsa tsoekere | ≤0.20% | 0.16% |
| Lintho Tse Amanang | ||
| Betadex Cyclodextrin | ≤0.25% | N/D |
| Ke mofuta oa Gamma Cyclodextrin | ≤0.25% | N/D |
| Lintho Tse Ling Tse Amanang | ≤0.50% | N/D |
| pH | 5.0~8.0 | 6.2 |
| Tlhahlobo ea Microbiological | ||
| Kakaretso ea lipalo tsa Aerobic Microbial | ≤1000cfu/g | 30cfu/g |
| Kakaretso ea Molds & Yeasts Bala | ≤50cfu/g | <50cfu/g |
| Escherichia Coli | Absent | Absent |
| Salmonella | Absent | Absent |
| Infrared Spectrum | E Ikamahanya le Sebopeho | E lumellana |
| Tekanyetso ea Teko | USP41-NF36 | |
Sephutheloana:0.5kg//bag, 1kg/bag, 2kg/bag,10kg/bag, 25kg/Drum, kapa ho ya ka tlhokahalo ya moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.Ha e lumellane le lisebelisoa tse matla tsa oxidizing.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Matshwao a Kotsi Xi - E tenang
Likhoutu tsa Kotsi R36 - Ho teneha mahlong
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36 - Apara liaparo tse loketseng tsa tšireletso.
WGK Jeremane 3
RTECS GU2292000
TSCA Ho joalo
HS Code 3505100000
α-Cyclodextrin (α-CD) (CAS: 10016-20-3)ke saccharide e sa fokotseng ea cyclic e nang le likarolo tse tšeletseng tsa tsoekere tse hokahantsoeng ke libonto tsa alpha-1.4.E hlahisoa ke ketso ea cyclodextrin glucosyl transferase ho syrups ea starch ea hydrolysed.Sekoti sa alpha-Cyclodextrin se ka tlaase ho beta-Cyclodextrin, kahoo se sebelisetsoa ho lumella ho thehoa ha li-complexes tse kenyelletsoeng ka limolek'hule tse nyenyane.Tekanyo ea solubility ea Alpha-Cyclodextrin ka metsing ke 14.5 g/100ml @25°C, kahoo boemo bo hlokang ho qhibiliha ho hoholo ha cyclodextrin.
Alpha-cyclodextrin e sebelisoa haholo ho lithethefatsi, lijo, tatso le litlolo.Alpha-cyclodextrin e boetse e sebelisoa haholo tšimong ea chefo e bolaeang likokoanyana le ho lokisa metabolism ea lijalo le ho eketsa bongata ba lijalo.Haholo-holo cyclodextrin le ramification ea eona e ntlafalitsoeng ke lilemo tsena, tse ling tsa tsona ke solutizer ea bohlokoa, stablizer, releaser kapa lisebelisoa tse thusang tsa lithethefatsi tse entsoeng ka Entericoated, tse ling tsa tsona ke thepa ea lintho tse entsoeng ka macromolecular.
Sehlopha sa lijo Alpha cyclodextrin e nang le li-glucose tse 6 e na le sebaka se senyenyane sa cyclodextrins.E na le thuso bakeng sa ho qhibilihisa, ho tsitsisa kapa ho fana ka limolek'hule tse nyenyane, mohlala, boima bo tlaase ba molek'hule, tatso kapa metsoako ea monko o monate.Mokhahlelo oa lijo Alpha cyclodextrin e hlahisoa indastering ea lijo e le fiber e ncha e qhibilihang ka har'a lijo e nang le thepa e kholisang.
Cyclodextrin e na le lesoba bohareng ba sebopeho sa lesale, le athomo ea oksijene eo -CH- e tlamang ho glucoside.Ke sulfur-aqueous, 'me lihlopha tsa hydroxyl sebakeng sa 2, 3 le 6 tsa tsoekere ke hydrophilic.E ka sebelisoa ho kopanya limolek'hule tse ling hore e be likarolo tse kenyelletsoeng ka matla a fokolang a van der Waals.Lintho tse ngata li ka koaheloa ke cyclodextrins, ho kenyelletsa likhase tse ntle, li-halogen, lidae, monko o monate, meriana, lijo, chefo e bolaeang likokoanyana le li-preservative.Ka mor'a encapsulation, botsitso ba eona, volatility, solubility le reactivity li ntlafatsoa.Phello e khethehileng ea Cyclodextrin e etsa hore e be thepa ea encapsulation e sebelisoang haholo.
1. Tšebeliso ea Cyclodextrin indastering ea meriana e ka etsa encapsulation (encapsulation) ka lithethefatsi, e ka etsang (1) Lithethefatsi tse sa tsitsang li tsitsitse;(2) Deliquescence, adhesion kapa liquid powderization ea lithethefatsi;(3) Lithethefatsi tse sa tsitsang kapa tse sa tsitsang li ka qhibiliha (li-solubilized), joalo-joalo.
2. Ho sebelisoa indastering ea chefo e bolaeang likokoanyana cyclodextrin encapsulation stabilization, chefo e bolaeang likokoanyana e ka bolokoa le ho ntlafatsa katleho ea chefo e bolaeang likokoanyana.
3. Tšebeliso ea indasteri ea lijo cyclodextrin e sebelisoa indastering ea lijo, e na le liphello tse latelang: (1) Ho felisa le ho koahela monko o khethehileng;(2) Ntlafatso le ntlafatso ea sebopeho sa lisele tsa lijo;(3) phokotso le ho tlosoa ha tatso e babang;(4) Phello ea Antioxidant;(5) Ho boloka le ho ntlafatsa tatso.
4. Tšebeliso ea Cyclodextrin indastering ea letsatsi le letsatsi ea lik'hemik'hale ho etsa litlolo e ka boela ea sebelisoa e le emulsifier le ho ntlafatsa boleng.E boetse e na le deodorization (joalo ka ho kenyelletsa halitosis) le litlamorao tsa antiseptic, e ka sebelisoa bakeng sa sesepa sa meno, tlhahiso ea phofo ea leino.
5. Litšebeliso tse ling tsa ts'ireletso ea tikoloho li ka sebelisoa e le moemeli oa phekolo ea likhoerekhoere tse mafura.Mokelikeli o nang le metsi oa Cyclodextrin o sebelisetsoa ho hloekisa tanka ea oli, 'me mokelikeli o litšila o ka fumanoa hape oa phekoloa ho fumana oli ea mafura.
6. Tšebeliso ea cyclodextrin k'hemistri Cyclodextrin ke reagent ea bohlokoa ea lik'hemik'hale.Ha e le teng, matla a fluorescence a fluorochrome a tla eketseha haholo, kahoo e ka sebelisoa bakeng sa tlhahlobo ea liprotheine le amino acid.E ka boela ea sebelisoa ho arola lik'hemik'hale tse telele tsa manyolo, li-racemes, joalo-joalo.
Ntle le moo, adsorbent e entsoeng ka Cyclodextrin e ka sebelisoa bakeng sa papatso ea chromatographic.
Mosebetsi
1. α-Cyclodextrin Eketsa botsitso ba lintho tse bonahalang: Thibela ho ferekana, thibela sublimation;Anti-oxidation;Thibela ho senyeha ha optothermal;Ho senyeha ha lik'hemik'hale;Eketsa nako ea ho nepahala ha thepa.
2. α-Cyclodextrin Eketsa ho qhibiliha ha thepa le bioavailability.
3. α-Cyclodextrin ka ho thehoa ha motsoako oa ho kenyelletsa ho finyella monko o monate oa sekoahelo.
4. Lithethefatsi tsa α-Cyclodextrin Liquid ho kena boemong bo tiileng.
5. α-Cyclodextrin Ho thibela lithethefatsi - lithethefatsi, lithethefatsi - ho sebelisana pakeng tsa tlatsetso.
6. α-Cyclodextrin Fokotsa litla-morao.
Kopo
1. α-Cyclodextrin e sebelisetsoa ho eketsa botsitso ba lintho tse bonahalang: Thibela ho ferekana, thibela ho fokotseha;Anti-oxidation;
2. α-Cyclodextrin e sebelisetsoa ho thibela ho senyeha ha optothermal;Ho senyeha ha lik'hemik'hale;Eketsa nako ea ho nepahala ha thepa.
3. α-Cyclodextrin e sebelisetsoa ho eketsa ho qhibiliha ha lintho tse bonahalang le bioavailability.
4. Ka ho theha "inclusion complex" ho fihlela monko o monate oa sekoahelo.Sethethefatsi se metsi se be boemong bo tiileng.
5. α-Cyclodextrin e sebelisetsoa ho thibela lithethefatsi - lithethefatsi, lithethefatsi - ho sebelisana pakeng tsa tlatsetso.
6. α-Cyclodextrin e sebelisetsoa ho fokotsa litla-morao.
Meriana:
1. Ho eketsa solubility ea ho fumaneha ha baeloji
2. Ho ntlafatsa bioavailability
3. Ho lokisa kapa ho laola tokollo
4. Ho fokotsa chefo
5. Ho ntlafatsa botsitso
Cosmetic:
1. Ho lumellana le encapsulation ea metsoako e sa tsitsang.
2. Ho eketsa bophelo ba lishelefo tsa litlolo tse turang.
Lijo:
1.Ho thibela ho fetoha mouoane ha lintho tse feto-fetohang.
2.Ho tlosa monko o mobe.
3.Ho ntlafatsa haholo litlamorao tsa emulsification
α-Cyclodextrin e fumanoa ho theha motsoako o tiileng o nang le mafura a lijo.Ka tsela ena e fokotsa bioavailability le ho monya ha mafura.E tsebahala ka ho laola maemo a triglyceride le leptin serum.Mehlala ea litoeba, α-Cyclodextrin e bontšoa ho susumetsa kutloisiso ea insulin le ho ntša mafura a mantle.Kahoo, α-Cyclodextrin e nkoa e sebetsa hantle bakeng sa ho phekola botenya le metabolic syndromes.
E kenyelelitsoe ho FDA Inactive Ingredients Database: α-Cyclodextrin (litokisetso tsa ente);β-Cyclodextrin (matlapa a molomo, li-gels tsa lihlooho);γ-Cyclodextrin (liente tsa IV).E kenyelelitsoe Lethathamong la Canada la Lintho tse Amohelehang tse sa Amoheleheng (moemeli oa botsitso; moemeli oa solubilizing);le metswakong ya meriana ya molomo le ya rectal e nang le laesense Europe, Japan, le USA.
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