Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) Excipients ea Pharmaceutical
Ruifu Chemical ke moetsi ea ka sehloohong oa Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Hydroxypropyl-β-Cyclodextrin |
| Litlhaloso tse tšoanang | Cyclodextrin HPB;Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl) -beta-Cyclodextrin;beta-Hydroxypropylcyclodextrin;HBC;HPBCD;HP-β-CD |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 128446-35-5 |
| Foromo ea limolek'hule | C63H112O42 |
| Boima ba Molek'hule | 1541.54 g/mol |
| Melting Point | 262.0~269.0℃ |
| Botenya | 1.05 |
| Phetoho e khethehileng [a]20/D | +120° ho ea +135° (C=1, H2O) |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing |
| COA & MSDS | E fumaneha |
| Mohlala oa mahala | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo e tšoeu, e se nang molato, e se nang molato | E lumellana |
| IR Spectrum | Li-Absorption Band tse tšoanang tse nang le USP Hydroxypropyl Betadex RS | E lumellana |
| pH | 5.0~7.5 | 6.57 |
| Ho Hlakola ha Tharollo | Tharollo e Hlakileng le e se nang Mebala | E lumellana |
| Tahlehelo ka ho Omisa | ≤10.0% | 3.5% |
| Masalla a ho Ignition | ≤0.20% | 0.09% |
| Litšepe tse boima | ≤20ppm | <10ppm |
| Chloride | ≤0.05% | <0.05% |
| Phapanyetsano ea Molar | 0.4 ~ 1.5 | 0.63 |
| Boikhantšo | 10% (w / v) Tharollo ea Metsi ≤200μS / cm | 154µS/cm |
| Degree of Substitution | 2.8~10.5 | 5.3 |
| Betadex e setseng | ≤1.50% | 0.12% |
| Propylene Glycol | ≤2.50% | 0.29% |
| Propylene oxide | ≤1ppm | <1ppm |
| Tšilafalo efe kapa efe e 'Ngoe | ≤0.25% | <0.25% |
| Kakaretso ea Litšila Tse Ling | ≤1.00% (ntle le Betadex le Propylen Glycol) | 0.51% |
| TAMC | ≤1000cfu/g | 30cfu/g |
| TYMC | ≤100cfu/g | 10cfu/g |
| Escherichia Coli | Ha e Fumanehe | E lumellana |
| Salmonella | Absent | Absent |
| Likokoana-hloko tsa Endotoxins | <10IU/g | <10IU/g |
| Qetello | E Lekoa 'me e Lumellana le Maemo a USP35 | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.Ha e lumellane le lisebelisoa tse matla tsa oxidizing.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
| Tlhaloso ea Tšireletseho | 24/25 - Qoba ho kopana le letlalo le mahlo. |
| WGK Jeremane | 3 |
| RTECS | GU2293332 |
| Khoutu ea HS | 3505100000 |
Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) ke cyclodextrin e fetotsoeng ka ho fetisisa, e leng lipophilic cavity e entsoeng ke lihlopha tsa 7 tsa glucose.Ho qhibiliha ha lithethefatsi metsing ho matlafatsoa haholo ke ho kopanya le HP-β-CD.Ho roala ka Enteric, mekhoa e tsitsitseng ea tokollo, phepelo ea lithethefatsi ea buccal le transdermal.
Hydroxypropyl-β-Cyclodextrin, e tsoang ho hydroxyalkyl, e fumana kopo e le koloi e entsoeng e sebelisetsoang ho matlafatsa ho qhibiliha ha meriana ka tharollo ea metsi bakeng sa ho fana ka katleho ea li-agent tsa bongaka tsamaisong ea likokoana-hloko.Ka kakaretso e sebelisoa e le sebaka sa α-, β- le γ-Cyclodextrins.
Hydroxypropyl betadex e 'nile ea etsoa lipatlisiso tse ngata ho meriana' me e sebelisitsoe haholo-holo e le solubilizer bakeng sa limolek'hule tsa hydrophobic ka metsi a molomo, li-solids tsa molomo, li-parenterals, li-inhaler tsa metered tse hatelitsoeng, li-inhalers tsa phofo e omileng, le metsoako ea lihlooho.E boetse e bontšitsoe hore e sebetsa e le stabilizer nakong ea ho sebetsa le ho boloka metsoako.Hydroxypropyl betadex inclusion complexes ho tlalehiloe ho bonts'a thepa ea mochini e fapaneng le lisebelisoa tse hloekileng.Monyetla o tlalehiloeng oa hydroxypropyl betadex ho feta b-cyclodextrin e sa nkeloang sebaka ke ho qhibiliha ha eona ho hoholo ha metsi.
1. Solubilization le solubilization, etsa hore lithethefatsi tse sa tsitsang li qhibilihe, li ntlafatse ho qhibiliha ha likarolo tse sebetsang tsa lithethefatsi tse mafura, ho lebisa tlhokomelo ea lithethefatsi le ho sireletsa katleho ea metsoako ea lithethefatsi.
2. Ntlafatsa bioavailability ea lithethefatsi, eketsa phello ea pheko ea lithethefatsi kapa fokotsa litekanyetso.
3. Fetola kapa ho laola sekhahla sa ho lokolloa ha lithethefatsi ho fokotsa litla-morao.
4. Koahela monko o mobe.
1) Lefapheng la meriana,
1. Hydroxypropyl Beta Cyclodextrin e ka eketsa ho qhibiliha ha moriana le ho fumaneha ha likokoana-hloko, hape ea eketsa phello e ntle le ho fokotsa tekanyo.
2. HP-β-CD e ka laola kapa ea fetola lebelo le sebetsang, ea fokotsa chefo ea lithethefatsi le ho matlafatsa botsitso ba lithethefatsi.
3. Sehlahisoa se loketseng sa ente le li-excipients tsa lithethefatsi ka lebaka la ts'ebetso e tlase ea holim'a metsi le ts'ebetso ea hemolytic, ha ho na ho teneha ha mesifa.
4. HP-β-CD ha e sebelisoe feela ka lithethefatsi tsa molomo, ente, tsamaiso ea ho fana ka lithethefatsi ea mucosal, tsamaiso ea phepelo ea lithethefatsi ea transdermal, lipotropy e lebisang tlhokomelo ea motho ea tsamaisang lithethefatsi, empa hape e ka sebelisoa e le protheine e sireletsang moemeli le stabilizer.
5. Ho ntlafatsa thepa ea organoleptic ea liketso tse babang kapa tse sa thabiseng.
2) Sebakeng sa lijo,
1. HP-β-CD e ka thibela ho fetoha mouoane ha lintho tse sa tsitsang ho boloka botsitso ba limatlafatsi tsa eona, ho tlosa monko o tšabehang 'me ho ka ntlafatsa haholo liphello tsa emulsification ka tšebeliso e kopanetsoeng ea li-emulsifiers tsa lijo.
2. HP-β-CD e ka boela ea etsa hore lijo li lokolloe butle-butle, tsa phahamisa phello ea anti-corrosion le ho lelefatsa sethala sa bophelo ba lijo.
3) Ka indasteri ea Litlolo
1. Ka litlolo tse tala tse sebelisoang e le stabilizer, emulsifier, solubilizer joalo-joalo.
2. HP-β-CD e ka fokotsa ho susumetsa letlalong, le ho matlafatsa botsitso ba likarolo tse sebetsang hantle.
3. HP-β-CD e ka fokotsa kapa ea pata monko o mobe oa molek'hule ea phepo.
4. Thibela ho hlophisoa ha limatlafatsi tse feto-fetohang, oxidation, eketsa infusibility, essence, monko o monate o qhibilihang ka metsing le ho boloka monko o lieha ho lokolloa le ho tšoarella.
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