Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory High Quality
Fana ka Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Mosifa oa Skeletal Relaxant.Calcium Channel Inhibitor
API Boleng bo Phahameng, Tlhahiso ea Khoebo
| Lebitso la Lik'hemik'hale | Dantrolene Sodium Letsoai Hydrate |
| Litlhaloso tse tšoanang | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate |
| Nomoro ea CAS | 14663-23-1 |
| Nomoro ea KAtse | RF-API78 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | C14H11N4NaO5 |
| Boima ba Molek'hule | 338.25 |
| Solubility | E qhibiliha ka DMSO |
| Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Bosehla-Namune ho isa ho Orange Crystalline Powder.Ha ho na bopaki bo bonahalang ba ho silafatsoa ke taba ea kantle ho naha |
| Boitsebiso A | Monyetla oa IR (197K) |
| Boitsebiso B | Nako ea ho boloka tlhoro e kholo ea chromatogram ea tlhahlobo ea tlhahlobo e lumellana le e ho chromatogram ea tokiso e tloaelehileng, joalo ka ha e fumanoe tlhahlobong. |
| Boitsebiso C | E kopana le litlhoko tsa tlhahlobo ea lelakabe la Sodium (191) |
| Boitsebiso D | Karolo ea 1: Ho theoa pula e matla, e tšoeu, ea kristale Karolo ea 2: Pula ha e nyamele Karolo ea 3: Pula e qhibiliha ka ho feletseng Karolo ea 4: Ha ho pula e entsoeng |
| Litaba tsa Metsi (ka KF) | 14.5%~17.0% |
| Boholo ba Karolo | 90% ka tlase ho 200um |
| Tlhahlobo | 90.0% ~ 96.0% ea C14H10N405 motheong oa anhydrous |
| Lintho Tse Amanang | (HPLC, Area%) |
| Motsoako o amanang le A | ≤0.15% |
| Related Compound B | ≤0.50% |
| Motsoako o amanang le C | ≤0.30% |
| Metsoako e setseng | |
| Ethanol | ≤2000ppm |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Litšepe tse boima | ≤10ppm |
| Shelf Life | lilemo tse 2 |
| Tekanyetso ea Teko | United States Pharmacopoeia (USP) |
| Tšebeliso | Mosifa oa Skeletal Relaxant.Calcium Channel Inhibitor |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), ke molek'hule e nyenyane inhibitor ea Ryanodine receptor antagonist le Calcium channel inhibitor.Dantrolene Sodium Letsoai ke skeletal mesifa e khathollang, e thibelang intracellular Ca 2 + tokollo ho tswa ho sarcoplasmic reticulum.Thibelo ea ho lokolloa ha Ca2 + ho tloha ho sarcoendoplasmic reticulum, e amanang ka matla le ho tsosoa le ho fokotseha ha mesifa, e hlahisa phello e khathollang mesifa e amanang le Dantrolene.The neurotoxicity e hlahisoang ke ts'ebetso e phatlalalitsoeng ea glutamate e amahanngoa le ho phahama ho feteletseng ha maemo a cytoplasmic Ca2+, 'me Dantrolene ka ho loketseng e bontšoa e le moemeli oa methapo ea kutlo khahlanong le neurotrasmitter-induced excitotoxicity.Dantrolene, Letsoai la Sodium ke inhibitor ea RyR-1 le RyR-3.
