DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay >98.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa DAPT (GSI-IX) (CAS: 208255-80-5) e nang le boleng bo phahameng, γ-Secretase Inhibitor.Ruifu Chemical e fana ka letoto la li-amino acid le li-derivatives.Re ka fana ka lits'ebeletso tsa lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Reka DAPT,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | DAPT |
| Litlhaloso tse tšoanang | GSI-IX;γ-Secretase Inhibitor IX;gamma-Secretase Inhibitor;LY-374973;(3,5-Difluorophenylacetyl)-Ala-Phg-OtBu;(3,5-Difluorophenylacetyl) -L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N-[N-(3,5-Difluorophenacetyl)-L-Alanyl]-S-Phenylglycine t-Butyl Ester;(2S)-N-[2-(3,5-Difluorophenyl)acetyl]-L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Boemo ba Setoko | E teng thepeng e teng ka lebenkeleng |
| Nomoro ea CAS | 208255-80-5 |
| Foromo ea limolek'hule | Setšoantšo sa C23H26F2N2O4 |
| Boima ba Molek'hule | 432.47 |
| Botenya | 1.213 g/cm3 |
| Melting Point | 142.0 ~ 146.0℃ |
| E hloahloa | Mocheso o Mamela |
| Solubility | E qhibiliha ka DMSO |
| Mocheso oa polokelo. | Boloka ho 2-8 ℃ |
| COA & MSDS | E fumaneha |
| Brand | Ruifu Chemical |
| Lipolelo tsa Tšireletseho | 24/25 - Qoba ho kopana le letlalo le mahlo. | ||
| WGK Jeremane | 3 | Khoutu ea HS | 2922491990 |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu | E lumellana |
| Tahlehelo ka ho Omisa | <0.40% | 0.21% |
| Masalla a ho Ignition | <0.40% | 0.20% |
| Heavy Metals (as Pb) | ≤20ppm | <20ppm |
| Mokhoa oa ho hlahloba / oa ho hlahloba | >98.0% (HPLC) | 98.62% |
| Carbon ka Elemental Analysis | 62.1 ~ 64.1% | E lumellana |
| Nitrojene ka Elemental Analysis | 6.20~6.70% | E lumellana |
| Infrared Spectrum | E Ikamahanya le Sebopeho | E lumellana |
| Sekhahla sa NMR | E Ikamahanya le Sebopeho | E lumellana |
| Qetello | Sehlahisoa sena ka Tlhahlobo se lumellana le Boemo ba Khoebo | |
| Shelf Life | Likhoeli tse 24 ho tloha ka Letsatsi la Tlhahiso haeba li bolokiloe hantle | |
Sephutheloana: Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se pholileng, se omileng (lebenkeleng ho 2-8℃) le ntlo ea polokelo e nang le moea o tsoang hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
DAPT (GSI-IX) (CAS: 208255-80-5), inhibitor e matla le e khethehileng ea γ-secretase.DAPT ke inhibitor ea γ-secretase (IC50 ho li-neuron tsa mantlha tsa motho = 115 nM bakeng sa kakaretso ea Aβ kapa 200 nM bakeng sa Aβ42 ka ho khetheha).Tsamaiso ea molomo ea DAPT e bontšitsoe ho fokotsa maemo a Aβ bokong ba boko, cerebrospinal fluid le plasma ho tloha litoeba le likhoto.DAPT e thibela pontšo ea Notch e khothalletsang phapang ea neuronal ea lisele tse tlang pele.E ntlafatsa lisele tsa iPS ntle le oncogenes KLF4 le CMYC5.Cell e khonahala.DAPT e sebelisoa thutong ea sebopeho sa β-amyloid.DAPT e bontšitsoe ho thibela pontšo ea Notch lithutong tsa mafu a autoimmune le lymphoproliferative, joalo ka ALPS le lupus erythematosus, hammoho le kholo ea lisele tsa mofetše, angiogenesis, le phapang ea lisele tse bakoang ke batho tsa pluripotent.E thibela pontšo ea Notch in vitro.E thibela tlhahiso eohle ea Aβ le Aβ42 litsong tsa mantlha tsa batho (litekanyetso tsa IC50 ke 115 le 200 nM, ka ho latellana) ntle le phello ho maemo a APPα le APPβ.Tšitiso ea mali bokong e khonahala.Karolo ea 3D Growth matrix le karolo ea cerebral organoid differentiation media.
