Darunavir CAS 206361-99-1 Anti-HIV Purity ≥99.0% API High Purity HIV Protease Inhibitor
Phepelo ea MoetsiLihlahisoa tse Amanang le Darunavir:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Lebitso la Lik'hemik'hale | Darunavir |
| Litlhaloso tse tšoanang | TMC114;UIC-94017 |
| Nomoro ea CAS | 206361-99-1 |
| Nomoro ea KAtse | RF-API68 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | C27H37N3O7S |
| Boima ba Molek'hule | 547.66 |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
| Boitsebiso | MS/HNMR HPLC |
| Solubility | E qhibiliha ka DMSO, e Hanyenyane ka Metsing |
| Melting Point | 74.0 ~ 76.0℃ |
| Boitsebiso | 1H NMR |
| Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
| Lintho Tse Amanang | |
| Ho Se hloeke ho hoholo ho Leng | ≤0.30% |
| Litšila ka Kakaretso | ≤1.0% |
| Metsoako e setseng | Ethanol ≤0.30% |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Masalla a ho Ignition | ≤0.10% |
| Litšepe tse boima | ≤20ppm |
| Arsenic | ≤1.5ppm |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Darunavir (lebitso la lebitso Prezista, eo pele e neng e tsejoa e le TMC114) ke moriana oa protease inhibitor o sebelisoang ho alafa tšoaetso ea HIV.Darunavir ke khetho ea kalafo e khothaletsoang ea OARAC bakeng sa batho ba baholo le bacha ba sa tsebeng ho phekola le ba nang le boiphihlelo ka kalafo.Darunavir ke mofuta o mocha oa li-non peptide anti retroviral protease inhibitors kalafong ea AIDS.E qalisoa ka lekhetlo la pele ke lekala la Johnson pharmaceutical Iceland, Tibotec.Ke ea bioavailability e phahameng ka ho fetisisa ho tse 6 tsa protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir le ABT378/r).E sebetsa ka ho thibela ho thehoa ha likaroloana tsa kokoana-hloko e ncha le e hōlileng ka holim'a lisele tse nang le tšoaetso le ho thibela protease ea kokoana-hloko.Ha sehlahisoa se sebelisoa nako e telele, hangata se ka fokotsa vector ea kokoana-hloko ea HIV maling, sa eketsa palo ea lisele tsa CD4, sa fokotsa monyetla oa tšoaetso ea HIV, sa ntlafatsa bophelo le ho lelefatsa bophelo.E loketse batho ba baholo ba tšoaelitsoeng kokoana-hloko ea HIV empa ba se na phello ea tšebeliso ea litlhare tse seng li ntse li le teng tsa li-antiretroviral.Setlhare se tlameha ho kopanngoa le tšebeliso ea litekanyetso tse tlase tsa ritonavir kapa li-antiretroviral tse ling, molemong oa ho ntlafatsa ts'ebetso.Ts'ebetso ea antiviral in vitro e ka hlahlojoa ka ho ba khahlano le li-lymphocyte tse tšoaelitsoeng tse matla le tse sa foleng le li-lymphocyte maling a peripheral.
