Decitabine CAS 2353-33-5 Bohloeki>99.5% (HPLC) Feme
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Decitabine (CAS: 2353-33-5) e nang le boleng bo phahameng.Re ka fana ka COA, phano ea lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Haeba u thahasella sehlahisoa sena, ka kopo romella lintlha tse qaqileng ho kenyelletsa nomoro ea CAS, lebitso la sehlahisoa, bongata ho rona.Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Decitabine |
| Litlhaloso tse tšoanang | 5-Aza-2'-Deoxycytidine;5-Aza-1-(2-Deoxy-β-D-Ribofuranosyl)cytosine;5-Aza-CdR;5-Aza-dC;5-Deoxy-2'-Azacytidine;ZdCyd;DAC;β-Decitabine |
| Nomoro ea CAS | 2353-33-5 |
| Nomoro ea KAtse | RF2728 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C8H12N4O4 |
| Boima ba Molek'hule | 228.21 |
| Melting Point | 191℃(Dec.) |
| E hloahloa | Ha e Mamelle Moeeng, Ha e Mamele Mocheso |
| Solubility | Qhala ka DMSO;Hanyane ka Metsing |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
| Boitsebiso A | IR: Mohlala oa IR Spectrum o Tšoanang le oa Standard |
| Boitsebiso B | HPLC: RT ea Tlhōrō e Khōlō ea Tharollo ea Tlhahlobo e Tšoanang le ea Tharollo e Tloaelehileng |
| Boitsebiso C | PXRD: E ntle |
| Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) |
| Alpha | +56.0°~ 63.0° |
| Tahlehelo ka ho Omisa | <0.50% |
| Masalla a ho Ignition | <0.10% |
| Litšepe tse boima | <20ppm |
| Lintho Tse Amanang | |
| α-Decitabine | <0.20% |
| Tšilafalo e le 'Ngoe e sa Tsejoeng | <0.20% |
| Litšila ka Kakaretso | <0.50% |
| Metsoako e setseng | |
| DMSO | <0.50% |
| Methanol | <0.30% |
| Formate ea Methyl | <0.05% |
| Acetonitrile | <0.041% |
| Solubility | Colorless Clear 50 mg/ml, HOAc and H2O (1:1) Pass |
| Tekanyetso ea Teko | Maemo a Khoebo |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Mokhoa oa ho Reka?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisa 'marakeng oa lehae, Amerika Leboea, Europe, India, Russia, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Decitabine (CAS: 2353-33-5) (lebitso la khoebo la Dacogen), kapa 5-Aza-2'-Deoxycytidine.Ka lik'hemik'hale, ke analogue ea cytidine.Decitabine ke moemeli oa hypomethylating.Decitabine e qaliloe bakeng sa kalafo ea myelodysplastic syndromes (MDS).MDS ke sehlopha sa mathata a mali a amang moko oa masapo a bakang sebopeho se sa sebetseng le nts'etsopele ea lisele tsa mali.Ho feta moo, bakuli ba MDS ba na le kotsi e kholo ea ho hatela pele ho acute myeloid leukemia (AML).Liphekolo tse tloaelehileng li kenyelletsa tšelo ea mali, mabaka a kholo ea mali, le lithibela-mafu tsa prophylactic, empa mehato ena e mpa e ntlafatsa boleng ba bophelo ka liphello tse belaetsang phetohong ea maloetse.Le hoja transplantation ea stem-cell e le mokhoa o mabifi, o ka folisang, botsofali kapa litaba tse ling tse thata tsa bophelo bo botle ba bakuli ba bangata li ba thibela ho nahana ka khetho ena.Leha ho le joalo, tsoelo-pele ea morao-rao ho etiology ea motheo ea MDS, leha ho le joalo, e lebisitse ho nts'etsopele ea sehlopha se secha sa metsoako e tsejoang e le '' demethylating agents ''.Decitabine e latela kenyelletso e atlehileng ea DNA methyltransferase inhibitor Azacitidine ea pele.E etsa hypomethylates DNA ka ho thibela DNA methyltransferase.E sebetsa ka mokhoa o ts'oanang le oa Azacitidine, le hoja decitabine e ka kenngoa feela likhoeleng tsa DNA ha azacitidine e ka kenngoa liketane tsa DNA le RNA ka bobeli.Li-reagents tsa lipatlisiso: Decitabine e sebelisoa haholo ho baeloji ea limolek'hule, pharmacology, le lipatlisiso tse ling tsa mahlale.Decitabine e le DNA methyltransferase inhibitor e khethehileng, ts'ebetso e fetolehang ea DNA methylation, e kentse lisele tsa tumor ho lisele tse tloaelehileng ho khetholla kapa ho kenya tumor cell apoptosis.Ka kopo hlokomela hore khatello e phahameng ea Decitabine e ka bapala phello ea eona ea cytotoxic: e ka thibela DNA synthesis e bakang lefu la sele.
