Desmopressin Acetate CAS 16789-98-3 Peptide Purity (HPLC) ≥98.5% Factory
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Desmopressin Acetate (CAS: 16789-98-3) e nang le boleng bo phahameng.Ruifu Chemical e fana ka letoto la li-peptide tsa GMP.Ruifu e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, palo e nyane le e ngata e fumanehang.Reka Desmopressin Acetate,Please contact: alvin@ruifuchem.com
Lebitso la Lik'hemik'hale | Desmopressin Acetate |
Litlhaloso tse tšoanang | Desmopressin (Acetate);DDAVP;1-(3-Mercaptopropanoic Acid) -8-d-Arginine Vasopressin Monoacetate;8-d-Arginine-1-(3-Mercapto-Propanoic Acid)vasopresin Monoacetate;Adiuretin SD;Desmospray;Minirin;Octim;Octostim;Presinex;Stimate |
Tatelano | Mpr-Tyr-Phe-Gln-Asn-Cys-Pro-DArg-Gly-NH2 (Mpr1 & Cys6 Bridge) |
Boemo ba Setoko | E teng thepeng e teng ka lebenkeleng |
Nomoro ea CAS | 16789-98-3 |
Foromo ea limolek'hule | C46H64N14O12S2.2(C2H4O2) |
Boima ba Molek'hule | 1189.32 g/mol |
E hloahloa | Hygroscopic.E Mamela Mongobo |
Mocheso oa polokelo. | Sebaka se pholileng le se omileng (-20℃).Sehatsetsi Tlas'a Sepakapaka sa Inert |
COA & MSDS | E fumaneha |
Letsatsi la ho felloa ke nako | Likhoeli tse 24 ho tloha ka Letsatsi la Tlhahiso haeba li bolokiloe hantle |
Brand | Ruifu Chemical |
Lintho | Maemo a Tlhahlobo | Liphetho |
Ponahalo | Phofo e tšoeu ea Fluffy | E lumellana |
Boitsebiso ka HPLC | Ho boloka hoa Tšoanang le Reference Substance | E lumellana |
Potoloho e Khethehileng [α]20/D | -72.0° ho ya ho -82.0° (C=1, 1% HAc) | -75.7° |
Sebopeho sa Amino Acid | Asp: 0.95 ~ 1.05 | 0.98 |
Matla: 0.95 ~ 1.05 | 0.98 | |
Pro: 0.95 ~ 1.05 | 1.01 | |
Boima: 0.95 ~ 1.05 | 1.00 | |
Sekhahla: 0.95 ~ 1.05 | 1.01 | |
Phe: 0.95 ~ 1.05 | 0.97 | |
Tyr: 0.70 ~ 1.05 | 0.99 | |
Cys: 0.30 ~ 1.05 | 0.78 | |
Peptide Purity (HPLC) | ≥98.5% | 99.3% |
Lintho tse Amanang ( HPLC) | Kakaretso ea Litšila: ≤ 1.5% | 0.78% |
Tšilafalo e Khōlō ka ho Fetisisa a le Mong: ≤ 0.5% | 0.16% | |
Litaba tsa Acetate (HPLC) | 3.0~8.0% | 7.6% |
Litaba tsa Metsi (Karl Fischer) | ≤6.0% | 1.0% |
Ho beleha | ≤50 CFU/100 mg | E lumellana |
Likokoana-hloko tsa Endotoxins | ≤5 IU/mg | E lumellana |
Tlhahlobo | 95.0 ~ 105.0% (E senang metsi, Acetic Acid Free) | 98.6% |
Tšimoloho ea Sehlahisoa | Synthetic | Synthetic |
Tlhokomeliso | Feela Bakeng sa Lipatlisiso, Eseng Bakeng sa Tšebeliso ea Batho | |
Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso |
Sephutheloana:Vial ea polasetiki (e nehetsoeng ho paka peptide) kapa vial ea khalase, bongata ho latela tlhoko ea lintlha tsa moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng le se omileng (-20℃) hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Fana ka lefatše ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Matshwao a Kotsi Xn - A Kotsi
Kotsi Codes 20 - Kotsi ka ho hema
Tlhaloso ea Polokeho 36 - Apara liaparo tse loketseng tse sireletsang.
WGK Jeremane 3
Desmopressin Acetate (CAS: 16789-98-3) ke hore, 1-cysteine deamination le 8-D-arginine sebakeng sa 8-l-arginine, e tsejoang hape e le arginine vasopressin, ke analog ea sebopeho sa arginine vasopressin ea tlhaho, e tsoang ho vasopressin, phello ea eona ea antidiuretic e matla ebile e tšoarella ho feta vasopressin, empa ha e na phello ea vasoconstrictor, litla-morao tsa lithethefatsi, tleliniki bakeng sa ho se sebetse ha platelet ea congenital kapa lithethefatsi, uremia, cirrhosis ea sebete le lisosa tse sa tsejoeng tse bakoang ke nako e telele ea mali;E ka sebelisoa ho laola le ho thibela ho tsoa mali nakong ea opereishene e nyane;Bohareng ba lefu la tsoekere insipidus.Maemong a motho ka mong, sehlahisoa sena se tla hlahisa katleho ho bakuli ba nang le mafu a itekanetseng a tsamaiso ea moroto, hangata ba holofetseng ho bakuli ba nang le lefu la Type IIB von Willebrand.
Ketso ea Pharmacological: Desmopressin Acetate e na le desmopressin e ka sebopeho se ts'oanang le ea native arginine vasopressin.Ke phapang pakeng tsa arginine vasopressin, haholo-holo bakeng sa halofo ea amino acid le D arginine ho nkela L Arginine sebaka.Liphetoho tsena tsa sebopeho li lelefatsa nako ea ts'ebetso ea tekanyetso ea kliniki ea desmopressin ntle le litlamorao tsa khatello.Liphuputso tse ling li bontšitse hore phello ea anti-enuresis e bohlokoa, e ka 'nang ea bakoa ke ho eketseha ha maemo a arginine vasopressin maling a bana bosiu, ebe o tsepamisa mohopolo morotong, o fokotsa molumo oa moroto le khatello ea methapo ea mali, ho fokotseha ha molala le khatello ea mali. detrusor contraction.
Ho sebetsa ha eona, boiketlo ba tsamaiso (intranasal), nako e telele ea ts'ebetso, le khaello ea litlamorao li e etsa sethethefatsi se ikhethileng bakeng sa kalafo ea lefu la tsoekere le bohareng.E ka boela ea tsamaisoa ka intramuscularly orntravenously.E khethoa ho feta ente ea vasopressin le li-antidiuretics tsa molomo tse sebelisoang ho bana.E bontšoa ke taolo ea nakoana ea polydipsia le polyuria e amanang le ho sithabela maikutlo kapa ho buuoa sebakeng sa pituitary.
Tšebeliso ea Tleliniki: Desmopressin, joalo ka letsoai la acetate, ke analogue ea maiketsetso ea vasopressin moo N terminal Cys e senang tšebetso ea eona ea α-amino (1-Deamino) le moo Arg8 e leng teng e le D-isomer (D-Arg8) , kahoo ke khutsufatso ea khoebo ea DDAVP.Ho ba teng ha D-Arg le ho ba sieo ha N-terminal amine mohahong oa desmopressin ho ekelitse halofo ea bophelo ba eona hoo e ka fumanehang bakeng sa tšebeliso ea molomo, ea motsoali kapa ea nko.E sebelisoa ke litsela tsena tse tharo tsa tsamaiso ho thibela kapa ho laola polydipsia (lenyora le feteletseng), polyuria, le dehydration ea bakuli ba nang le lefu la tsoekere insipidus e bakoang ke khaello ea vasopressin.E boetse e amohetsoe bakeng sa kalafo ea "neuresis" ea bosiu (bed-wetting), eo ho lumeloang hore e bakoa ke ho se be teng ha maemo a tloaelehileng a bosiu a vasopressin.Desmopressin e tsejoa ka ho baka keketseho ea bobeli ba plasma factor VIII (antihemophilic factor) le activator ea plasminogen.Ka hona e amohetsoe ke US FDA bakeng sa tšebeliso, ka botsoali le ka nko, ho fokotsa liketsahalo tsa ho tsoa mali ka tšohanyetso kapa tse bakoang ke ho sithabela ho bakuli ba nang le lefu la haemophilia A le mofuta oa I Von Willebrand's, ha feela mosebetsi oa bona oa plasma factor VIII o feta 5%.Stimate, nasal spray e sebelisoang ho phekola bakuli ba nang le haemophilia A le mofuta oa I Von Willebrand's disease, ke makhetlo a 15 a mangata a DDAVP nasal spray;ea ho qetela e sebelisoa ho phekola lefu la tsoekere insipidus.