Desquinolinyl Lenvatinib CAS 796848-79-8 Bohloeki >99.0% (HPLC) Lenvatinib Mesylate Intermediate Factory

Tlhaloso e Khutšoanyane:

1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

Mantsoe a tšoanang: Desquinolinyl Lenvatinib

CAS: 796848-79-8

Bohloeki: >99.0% (HPLC)

Ponahalo: Bosoeu bo Bosoeu ho isa ho Bokhubelu ba Phofo e tiileng ea Brown

Bohareng ba Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea
Litlhaloso tse tšoanang Desquinolinyl Lenvatinib;Tšilafalo ea Lenvatinib 16;Tšilafalo ea Lenvatinib Desquinolinyl;Tšilafalo ea Lenvatinib LFS-A;Lenvatinib Mesylate Mahareng Ⅲ;N-(2-Chloro-4-Hydroxyphenyl)-N'-Cyclopropyl-Urea
Nomoro ea CAS 796848-79-8
Nomoro ea KAtse RF-PI1972
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C10H11ClN2O2
Boima ba Molek'hule 226.66
Ntlha e belang 364.6±42.0℃
Botenya 1.43±0.10 g/cm3
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Phofo e tiileng e bosoeu ho isa ho e khubelu e sootho
Mokhoa oa Bohloeki / Analysis >99.0% (HPLC)
Mongobo (KF) <0.50%
Masalla a ho Ignition <0.20%
Tšilafalo e le Mong <0.50%
Litšila ka Kakaretso <1.00%
Litšepe tse boima <10ppm
Infrared Spectrum E Ikamahanya le Sebopeho
NMR E Ikamahanya le Sebopeho
Tekanyetso ea Teko Maemo a Khoebo
Tšebeliso Bohareng ba Lenvatinib Mesylate (CAS: 857890-39-2)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

1

LBH:

Kopo:

1-(2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea, eo hape e tsejoang e le Desquinolinyl Lenvatinib, (CAS: 796848-79-8) ke ho se hloeke ha lipakeng kapa ho se hloeke ha Lenvatinib Mesylate (CAS: 857890-39-2).Desquinolinyl Lenvatinib ke metabolite ea Lenvatinib Mesylate e leng inhibitor e sebetsang ka molomo ea multiple receptor tyrosine kinases ho akarelletsa VEGF, FGF le SCF receptors.Lenvatinib ke setlhare se thibelang mofets'e bakeng sa kalafo ea mefuta e itseng ea mofets'e oa qoqotho, 'me mohlomong le mefets'e e meng.Ka la 13 Hlakola, 2015, US FDA e amohetse sethethefatsi sa anticancer Lenvatinib bakeng sa kalafo ea mofets'e oa qoqotho.Lenvatinib ke inhibitor ea enzyme e nang le lipheo tse ngata, e khonang ho thibela VEGFR2 le VEGFR3 (vascular endothelial growth factor receptor).Lebitso la khoebo la Lenvatinib ke Lenvima.

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