Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV

Tlhaloso e Khutšoanyane:

Lebitso: Entecavir

CAS: 142217-69-4

Ponahalo: Phofo e tšoeu ea Crystalline

Setlhare sa antiviral se sebelisetsoang ho phekola lefu la Hepatitis B

API Boleng bo Phahameng, Tlhahiso ea Khoebo

Inquiry: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Entecavir
CAS: 142217-69-4
Setlhare sa antiviral se sebelisetsoang ho phekola lefu la Hepatitis B
API Boleng bo Phahameng, Tlhahiso ea Khoebo

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Entecavir
Litlhaloso tse tšoanang	2-Amino-1,9-dihydro-9-[(1S,3R,4S) -4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopenyl] -6H-purin-6-one
Nomoro ea CAS	142217-69-4
Nomoro ea KAtse	RF-API80
Boemo ba Setoko	Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma
Foromo ea limolek'hule	C12H15N5O3
Boima ba Molek'hule	277.28
Melting Point	249.0~252.0℃
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Tšoeu ea Crystalline
Boitsebiso ba IR	Sekhahla sa ho monya ha infraed sa sampole ea teko se tlameha ho ikamahanya le maemo a litšupiso
Boitsebiso ba HPLC	Nako ea ho boloka sampole ea teko e tsamaisana le ea maemo a referense
pH	5.5~7.5
Specific Optical Rotation	+24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Lintho Tse Amanang
Litšila ka Kakaretso	≤0.30%
Ho se hloeke ho hoholo ho le Mong	≤0.10%
Enantiomer	≤0.20%
Metsoako e setseng
Methanol	≤0.30%
Dichloromethane	≤0.06%
n-Hexane	≤0.029%
Tetrahydrofuran	≤0.072%
N, N-Dimethylformamide	≤0.088%
Toluene	≤0.089%
Litaba tsa Metsi	5.8%~6.5%
Masalla a ho Ignition	≤0.10%
Litšepe tse boima	≤20ppm
Tlhahlobo	98.0%~102.0% (C12H15N5O3 e baloang ho latela anhydrous)
Boholo ba Karolo	D90: ≤100µm
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	API, lithethefatsi tse thibelang likokoana-hloko tse sebelisoang ho phekola tšoaetso ea Hepatitis B

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

LBH:

Kopo:

Entecavir ke moloko o mocha oa guanine nucleoside analogues oral medicine bakeng sa phekolo ea tšoaetso ea Hepatitis B Virus (HBV), haholo-holo bakeng sa phekolo ea bakuli ba baholo ba nang le ts'ebetso ea kokoana-hloko ea kokoana-hloko le serum transaminase e ntse e eketseha, kapa lisele tsa sebete bakeng sa ts'ebetso ea pathological ea lefu la sebete la B le sa foleng. , hajoale e theohile kokoana-hloko e lebelo ka ho fetisisa le e matla ka ho fetisisa, lebelo la phetoho e tlaase ka ho fetisisa la li-nucleoside analogues.Data bontša hore fapaneng ho bakuli ba sa foleng lefu la sebete B, ho akarelletsa le nucleoside naive le nucleoside tšoaroa le sebete ho thatafala ha sebete bakuli, ho sebelisa matlapa hantle entecavir kalafo ka laola lefu lena ka potlako 'me ha bonolo fihla kalafo ea 'nete qetellong, e leng kokoana-hloko ea lefu la sebete B e sa lekanyetsoang;ka ho khomarela kalafo, karolo e kholo ea bakuli e ka fihla qetellong ea khotsofalo ea phekolo, e leng phetoho ea antigen serology, bakuli ba bang ba ka ba ba fihla se loketseng bakeng sa phekolo ea ho qetela, e leng holim'a antigen negative.