Erlotinib Hydrochloride CAS 183319-69-9 Purity >99.0% (HPLC) Setšoantšo se Featured

Erlotinib Hydrochloride CAS 183319-69-9 Bohloeki >99.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Erlotinib Hydrochloride

Mantsoe a tšoanang: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Bohloeki (HPLC): >99.0%

Ponahalo: Bosoeu ho isa ho Bosoeu ba Crystalline Powder

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Moetsi ea ka sehloohong le mofani oa thepa ea Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Erlotinib Hydrochloride
Litlhaloso tse tšoanang	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxy) -4-(3-ethynylanilino)quinazoline Hydrochloride;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl
Nomoro ea CAS	183319-69-9
Nomoro ea KAtse	RF-PI2242
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C22H24ClN3O4
Boima ba Molek'hule	429.90
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo ea Crystalline e tšoeu ho isa ho e tšoeu
Boitsebiso	A: IR: E Ikamahanya le Reference Spectrum B: HPLC: E Ikamahanya le Reference RT
Solubility	Ha Hanyane Hanyenyane ka Metsing, Ha Hanyenyane Hanyenyane ka Methanol 'me ha e khonehe ho Acetonitrile, Acetone, Ethyl Acetate le Hexane.
Melting Point	223.0~229.0℃
Tahlehelo ka ho Omisa	<0.50%
Masalla a ho Ignition	<0.20%
Litšepe tse boima	<20ppm
Tšilafalo e le Mong	<0.50%
Litšila ka Kakaretso	<1.00%
Metsoako e setseng
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Mokhoa oa Bohloeki / Analysis	>99.0%
Mokhoa oa ho hlahloba / oa ho hlahloba	98.5%~101.0% (E baloa ka Motheo oa Anhydrous)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	API

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

Erlotinib Hydrochloride (CAS: 183319-69-9) ke molek'hule e nyane ea epidermal growth factor receptor tyrosine kinase reversible inhibitor, e sebelisoa haholo kalafong ea mofets'e oa mofets'e o seng o monyane oa sele ea matšoafo le kalafo ea mela ea bobeli kapa e meraro. kankere ea pancreatic.Erlotinib Hydrochloride e amohetsoe ka Pulungoana, 2004, bakeng sa kalafo ea mofetše oa matšoafo o tsoetseng pele kapa oa metastatic o seng o nyane.Ke ea sehlopha se tšoanang le Gefitinib, quinazoline e 'ngoe e amohelehang bakeng sa phekolo ea kankere ea matšoafo e tsoetseng pele, empa e na le thepa e ntlafetseng ea pharmacokinetic.Molek'hule e thehiloe ke Pfizer mme nts'etsopele e qalile ka ts'ebelisano le OSI, e neng e nka litokelo tse feletseng tsa lithethefatsi ha Pfizer e kopana le Warner Lambert.Kamora moo, Genentech/Roche e ile ea kena tumellanong ea laesense le OSI ho nts'etsapele le ho bapatsa sethethefatsi sena US le Lefatšeng ka Bophara.Khetho ea epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitor.Antineoplastic.Erlotinib Hydrochloride ke HER1/EGFR inhibitor e nang le IC50 ea 2 nM.Erlotinib HCl e fumaneha e le matlapa a 25-, 100-, le 150-mg bakeng sa tsamaiso ea molomo.