Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate
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Lebitso la Lik'hemik'hale | Ethyl (S) -4-Chloro-3-hydroxybutyrate |
Litlhaloso tse tšoanang | (S) -4-Chloro-3-hydroxybutyric Acid Ethyl Ester |
Nomoro ea CAS | 86728-85-0 |
Nomoro ea KAtse | RF-PI139 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C6H11ClO3 |
Boima ba Molek'hule | 166.6 |
Botenya | 1.19 g/mL ho 25℃ (lit.) |
Refractive Index | n20/D 1.453 (lit.) |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Mokelikeli o se Nang Mebala ho ea ho o Bosehla bo Bosehla |
Mokhoa oa Bohloeki / Analysis | ≥98.0% (GC) |
Mongobo (KF) | ≤0.50% |
Ethyl-4-Chloro Aceto Acetate | ≤0.50% |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Pharmaceutical Intermediate;Organic Synthesis |
Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Mokhoa oa ho hlahloba
Tlhaloso
Nka sampuli ea 10ml ka poleiti ea khalase e hloekileng le e omeletseng 'me u hlahlobe.
Ho potoloha ho itseng
Fetisetsa ka nepo hoo e ka bang 1.0g ea sampole ho 100ml volumetric flask mme e qhibilihisitsoe ka har'a10 ml ea chloroform, ebe o hlapolla ka chloroform ho 100ml ebe o kopanya.
Lekanya potoloho ea optical ea sampole ea teko ho 25ºC le 589nm wavelengthbala ho potoloha ho itseng ho latela foromo e fanoeng.
[α]25D = (v×a)/[w×(1-b)]
[α]25D: potoloho e khethehileng ea tekomohlala;α: ho potoloha ho hlokometsoeng hotekanyo ea angular;w: boima ba mohlala (g);
v: bophahamo ba modumo (mL);
b: Likahare tsa metsi(%)
Purity (ka GC)
Maemo a Chromatographic: The Gas chromatography e na le lelakabemochine oa ionization
Kholomo: SE-54, 30m×0.35mm×0.25µm
Mocheso oa ontong: Mocheso oa pele oa 120 ℃, Tšoara nako bakeng sa 2min
Sebaka: 20 ℃/min
Mocheso: 250 ℃, Tšoara nako bakeng sa 2min
Mocheso oa ente: 250 ℃
Mocheso oa Mohloli: 250℃(FID)
Bophahamo ba ente: 0.2µl
Tharollo ea mohlala: hlapolla 1ml A4 ka 1ml acetone.
Mokhoa oa ho etsa: Kenya 0.2µl ea acetone e se na letho 'me u tlalehe chromatogram.Hochromatogram e fumanoang ho tswa ho diluent ha ea lokela ho ba le tšitiso leha e le efenako ya ho boloka sehlohlolong se seholo le tlhoro ya ditshila.Ho feta Enta sampole tharollo kakopitsa ka har'a chromatograph 'me u tlalehe chromatogram.Tlaleha Bohloeki basampole ka sebaka se tloaelehileng mokhoa.
Sephutheloana: Botlolo, Moqomo, 25kg/Moqomo, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
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Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Ethyl (S) -4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) e nang le boleng bo phahameng, ke ea bohareng ka tloaelo ho motsoako oa Atorvastatin. Calcium (CAS: 134523-03-8).
Atorvastatin Calcium (CAS: 134523-03-8) [lebitso la khoebo: Lipitor] e bontšoa haholo-holo bakeng sa phekolo ea lefu la pelo le lefu la dyslipidemia ka lebaka la phello ea eona ea ho theola k'holeseterole maling.Atorvastatin e sebetsa haholo-holo sebeteng.Ho fokotseha ha k'holeseterole ea sebete ho eketsa ho kenngoa ha k'holeseterole 'me ho fokotsa k'holeseterole ea plasma.Lipitor, ho tloha ka 1996, e fetohile moriana o rekisoang ka ho fetisisa lefatšeng ho fihlela nakong eo.
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