Etravirine TMC-125 CAS 269055-15-4 Assay ≥99.0% (HPLC) API Factory High Purity
Moetsi ea nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Etravirine (TMC-125)
CAS: 269055-15-4
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Etravirine |
Litlhaloso tse tšoanang | TMC-125 |
Nomoro ea CAS | 269055-15-4 |
Nomoro ea KAtse | RF-API54 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | Setšoantšo sa C20H15BrN6O |
Boima ba Molek'hule | 435.28 |
Botenya | 1.439 g/cm3 |
Boemo ba ho Romela | Tlas'a Mocheso oa Ambient |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e tiileng e tšoeu |
Boitsebiso | Ka IR, HPLC |
Melting Point | 211.0~216.0℃ |
Litaba tsa Metsi | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšepe tse boima | ≤20ppm |
Tšilafalo efe kapa efe e le 'Ngoe | ≤0.50% |
Litšila ka Kakaretso | ≤1.0% |
Tlhahlobo | ≥99.0% (HPLC) |
Tekanyetso ea Teko | Maemo a Khoebo |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Etravirine (TMC-125) (CAS 269055-15-4) ke moloko oa bobeli oa non-nucleoside reverse transcriptase inhibitor (NNRTI) o sebelisoang bakeng sa phekolo ea HIV.E bontšoa ho sebelisoa hammoho le li-antiretroviral tse ling bakeng sa ho alafa tšoaetso ea HIV-1 ho bakuli ba baholo ba nang le phihlelo ea phekolo ba nang le bopaki ba ho ikatisa ha kokoana-hloko le mefuta ea HIV-1 e hanyetsanang le li-NNRTI tse teng hona joale le li-antiretroviral tse ling.Li-NNRTI, hammoho le li-nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs), ke likarolo tsa bohlokoa tsa mekhoa e kopaneng e sebelisoang hajoale ho alafa tšoaetso ea HIV-1.Li-NRTIs/NtRTIs li sebetsa ka ho qothisana lehlokoa le li-nucleotide substrates tsa reverse transcriptase bakeng sa ho kenngoa ho DNA ea kokoana-hloko le ho felisoa ha ketane e latelang.Ka lehlakoreng le leng, li-NNRTI li tlamella sebakeng sa allosteric sa enzyme le ho senya tšebetso ea DNA polymerase ka ho etsa hore ho be le liphetoho tse amanang le sebaka sa catalytic.