Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiviral CMV Inhibitor High Quality
Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Ganciclovir
CAS: 82410-32-0
Moemeli oa Antiviral bakeng sa Phekolo ea Tšoaetso ea Cytomegalovirus (CMV).
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | "Ganciclovir" |
Litlhaloso tse tšoanang | GCV;BW 759;9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine;2-Amino-9- (1,3-dihydroxypropan-2-yloxymethyl) -3H-purin-6-one;2'-Nor-2'-Deoxyguanosine |
Nomoro ea CAS | 82410-32-0 |
Nomoro ea KAtse | RF-API82 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C9H13N5O4 |
Boima ba Molek'hule | 255.23 |
Melting Point | 250 ℃ |
Mocheso oa polokelo | 2-8℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Solubility | Ha Haholo Ha Hanyane ka Metsing |
Boitsebiso | Ho monya ha ultraviolet, ho monya ha infrared |
Tahlehelo ka ho Omisa | ≤6.0% |
Masalla a ho Ignition | ≤0.10% |
Lintho Tse Amanang | Ganciclovir Related Compound A ≤0.50% |
Moeli oa Guanine | ≤0.50% |
Residual Solvents (GC) | Ethanol ≤5000ppm |
Litšepe tse boima | ≤10ppm |
Absorption Coefficient | 516-548 ho 252nm |
Likokoana-hloko tsa Endotoxins | ≤0.84EU/mg |
Tlhahlobo | 98.0%~102.0% (Titration) |
Tekanyetso ea Teko | Maemo a Khoebo;United States Pharmacopoeia (USP) Standard |
Tšebeliso | API, CMV Inhibitor |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Ganciclovir (CAS 82410-32-0) ke ea lithethefatsi tse thibelang likokoana-hloko tsa nucleoside, e leng mofuta oa li-guanosine derivatives.Ganciclovir ke motsoako oa antiviral o sebetsang ka botsoali o bontšitsoeng bakeng sa ts'oaetso ea cytomegalovirus (CMV) e behang bophelo kotsing ho bakuli ba nang le immunocompromised.E na le liphello tse pharaletseng, tse matla haholo tse thibelang kokoana-hloko ea herpes 'me ke moriana oa pele oa khetho bakeng sa phekolo ea tšoaetso ea cytomegalovirus e nang le phello e matla ho kokoana-hloko ea hepatitis B le adenovirus hape.Ke homologue ea acyclovir (ACV) ka phello ea eona ea antiviral e ts'oanang le, empa e matla ho feta aciclovir, e nang le litlamorao tse matla haholo tse thibelang cytomegalovirus e amanang le bakuli ba AIDS.E sebelisoa bakeng sa kalafo ea mohato oa induction le mohato oa tlhokomelo ho bakuli ba nang le immunocompromised (ho kenyeletsoa bakuli ba AIDS) ba nang le cytomegalovirus retinitis.E ka boela ea sebelisoa bakeng sa ho thibela lefu la cytomegalovirus bakeng sa bakuli ba amohelang litho tsa 'mele kapa bakuli ba AIDS ba nang le liphello tse ntle tekong ea cytomegalovirus serology.
Ganciclovir (CAS 82410-32-0) ke inhibitor e sebetsang hantle haholo, e nang le chefo e tlaase le e phahameng ea khetho e entsoeng ke Syntex Company (United States).Ke moriana oa pele o amohetsoeng ke US FDA bakeng sa kalafo ea ts'oaetso ea cytomegalovirus (CMV).Syntex e filoe tokelo e khethehileng ea tlhahiso.Ka Phuptjane 1988, letlapa lena le amohetsoe ka lekhetlo la pele ho ngolisoa UK, 'me la lateloa ke ho amoheloa ka tatellano ke Fora, United States, Japane le Jeremane Bophirima, Italy le Canada le linaha tse ling.Ho fihlela bofelong ba June 1999, e amohetsoe linaheng tse fetang 70 le libaka bakeng sa thibelo ea bakuli ba immunodeficiency le tšoaetso ea cytomegalovirus ea bakuli ba ho fetisetsa litho tsa 'mele.Ka 2002, matlapa a Ganciclovir a fumane tumello ho FDA, a se a fumaneha hona joale.