Gefitinib CAS 184475-35-2 Bohloeki > 99.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Gefitinib (CAS: 184475-35-2) ka boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Gefitinib le li-intermediates,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Gefitinib |
| Litlhaloso tse tšoanang | Gefitinib Free Base;Iressa;ZD1839;ZD-1839;N-(3-Chloro-4-Fluorophenyl)-7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4-Amine;N-(3-Chloro-4-Fluorophenyl)-7-Methoxy-6-[3-(4-Morpholinyl) propoxy]-4-Quinazolinamine |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 184475-35-2 |
| Foromo ea limolek'hule | C22H24ClFN4O3 |
| Boima ba Molek'hule | 446.91 g/mol |
| Melting Point | 194.0 ho isa ho 198.0 ℃ |
| Botenya | 1.322±0.06 g/cm3 |
| Ho qhibiliha ha Metsi | Ha e qhibilihe ka Metsing |
| Solubility | E qhibiliha ka DMSO |
| Mocheso oa polokelo. | Mocheso oa Kamore |
| Ho tsamaisa ka sekepe | Ambient |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu | E lumellana |
| Tahlehelo ka ho Omisa | <0.50% | 0.13% |
| Masalla a ho Ignition | <0.20% | 0.06% |
| Tšilafalo e le Mong | <0.10% | 0.09% |
| Litšila ka Kakaretso | <0.50% | 0.20% |
| Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
| Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) | 99.80% |
| Infrared Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Ha e sebelisoe ho batho.Ha e sebelisoe litlhahlobong kapa litlhare.Bakeng sa tšebeliso ea lipatlisiso tsa in vitro feela.
Ha ho lihlahisoa tse tla fuoa linaha tseo ho tsona sena se ka bang se thulana le litokelo tsa molao tse teng.Leha ho le joalo boikarabello ba ho qetela bo ho Moreki.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
| Tlhaloso ea Tšireletseho | 24/25 - Qoba ho kopana le letlalo le mahlo. |
| Khoutu ea HS | 2934999099 |
Gefitinib (CAS: 184475-35-2) ke lithethefatsi tse khethehileng haholo tse khahlanong le tumor tse etselitsoeng phekolo e entsoeng ke AstraZeneca, UK.Ke moriana oa pele o lebisitsoeng ho molek'hule bakeng sa ho alafa mofetše o seng o monyenyane oa sele ea matšoafo.E sebetsa ka ho thibela ka mokhoa o ikhethileng tsela ea phetisetso ea matšoao ea epidermal growth factor receptor tyrosine kinase (EGFR-TK).Epidermal growth factor (EGF) ke polypeptide e nang le boima ba molek'hule ea 6.45 × 103, e ka kopanang le epidermal growth factor receptor (EGFR) ho lera le lebisitsoeng la sele ho hlahisa liphello tsa likokoana-hloko.EGFR ke mofuta oa tyrosine kinase (TK) receptor.Ha e tlama ho EGF, e ka khothalletsa ts'ebetso ea TK 'meleng oa moamoheli, e leng se hlahisang autophosphorylation ea masala a receptor tyrosine, ho fana ka lipontšo tse tsoelang pele tsa karohano ho lisele, ho baka ho ata ha lisele le ho arohana.EGFR e ngata liseleng tsa motho 'me e bonahala haholo ka lihlahala tse kotsi.Ka ho thibela tsela ea pontšo ea EGFR holim'a sele, gefitinib e sitisa ho hōla ha hlahala, metastasis le angiogenesis, 'me e ka etsa hore ho be le apoptosis ea lisele tsa tumor.Ka Phato 2002, gefitinib e ile ea rekisoa Japane ka lekhetlo la pele e le kalafo ea pele bakeng sa mofetše o seng o monyane oa lisele tsa matšoafo tlas'a lebitso la khoebo Iressa.Ka Mots'eanong 2003, Tsamaiso ea Lijo le Lithethefatsi ea US e ile ea amohela gefitinib e le mokhoa oa boraro oa kalafo ea monotherapy bakeng sa bakuli ba nang le mofetše oa matšoafo oa sele o seng o monyane ba neng ba sa sebetse ka litlhare tse thibelang mofetše tse thehiloeng ho platinum le chemotherapy ea docetaxel.Hajoale, e amohetsoe ke Australia, Japane, Argentina, Singapore le Korea Boroa bakeng sa kalafo ea mofetše o tsoetseng pele oa mofetše oa matšoafo oa sele o seng o monyane.Ka la 28 Hlakola, 2005, Tsamaiso ea Lijo le Lithethefatsi ea China e ile ea amohela gefitinib bakeng sa kalafo ea mofetše oa sele ea matšoafo o tsoetseng pele kapa oa metastatic o seng o monyane (NSCLC) o neng o kile oa fumana chemotherapy.Ha joale ha e so lumelloe ho sebelisoa e le phekolo ea pele bakeng sa NSCLC e tsoetseng pele.Ka la 1 Phupu 2009, European Medicines Agency e ile ea amohela ka molao gefitinib bakeng sa kalafo ea mothapo oa pele, oa bobeli le oa boraro bakeng sa mofetše oa sele ea matšoafo o tsoetseng pele kapa oa metastatic oo e seng o monyane o nang le phetoho ea liphatsa tsa lefutso tsa EGFR ho batho ba baholo.
