Glimipiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Purity
Fana ka Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Glimepiride
CAS: 93479-97-1
Glimepiride kalafong ea mofuta o sa itšetleheng ka insulin ea lefu la tsoekere mellitus
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Glimepiride |
Litlhaloso tse tšoanang | Amaryl |
Nomoro ea CAS | 93479-97-1 |
Nomoro ea KAtse | RF-API24 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | Setšoantšo sa C24H34N4O5S |
Boima ba Molek'hule | 490.62 |
Melting Point | 212.2 ~ 214.5 ℃ |
Boemo ba ho Romela | Tlas'a Mocheso oa Ambient |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e Tshweu kapa e Batlileng e Tshweu |
Boitsebiso | IR (E Tšoanang le E Tloaelehileng) |
Lintho Tse Amanang | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Urethane (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Tšilafalo E 'ngoe | ≤0.10% |
Litšila ka Kakaretso | ≤0.50% |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.10% |
Litšepe tse boima | ≤0.001% |
Tlhahlobo | 98.0%~102.0% |
Tekanyetso ea Teko | Pharmacopeia ea Europe (EP);United States Pharmacopoeia (USP) |
Tšebeliso | Active Pharmaceutical ingredient (API) |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Glimipiride (CAS: 93479-97-1) e nang le boleng bo phahameng, motsoako o sebetsang oa meriana (API).Glimipiride ke sethethefatsi sa antidiabetes se thusang ho laola maemo a tsoekere ea mali.Glimepiride ke sulfonylurea e sebetsang nako e telele, ea moloko oa boraro e nang le ts'ebetso ea hypoglycemic.
Glimepiride (lebitso la pele la khoebo Amaryl) ke sethethefatsi sa sulfonylurea se sebetsang ka nako e telele ho isa ho sa nako e telele.Joalo ka li-sulfonylureas tsohle, glimepiride e sebetsa joalo ka secretagogue ea insulin.E theola tsoekere ea mali ka ho susumetsa ho lokolloa ha insulin liseleng tsa pancreatic beta le ka ho eketsa kutloisiso ea lisele tsa peripheral ho insulin.Gliepiride e kanna ea hokahana le li-receptor tsa potasiamo tse utloang ATP ka holim'a sele ea pancreatic, e fokotsa ts'ebetso ea potasiamo mme e baka depolarization ea lera.Membrane depolarization e etsa hore calcium ion e kenelle ka likanale tsa khalsiamo tse utloang motlakase.Keketseho ena ea khalsiamo ea intracellular calcium ion e susumetsa tlhahiso ea insulin.Glimepiride e sebelisoa haholo ho phekola bakuli ba nang le lefu la tsoekere la mofuta oa 2 hape e ka fokotsa menyetla ea hore motho a be le mathata a lefu la tsoekere la mofuta oa 2.Setlhare se amohetsoe ke FDA ka 1995 mme se entsoe ke Sanofi-Aventis.E ka sebelisoa hammoho le lenaneo le nepahetseng la ho ja le ho ikoetlisa 'me e ka boela ea sebelisoa e le mong kapa le meriana e meng e thibelang lefu la tsoekere haeba ho hlokahala.Glimepiride e ka sebelisoa e le monotherapy kapa hammoho le insulin.