Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Bohloeki >99.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Ibrutinib Deacryloylpiperidine

CAS: 330786-24-8

Bohloeki: >99.0% (HPLC)

Ponahalo: Off-White to Khaki Powder

Bohareng ba Ibrutinib (CAS: 936563-96-1)

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Likahare tse Amanang le Ibrutinib:
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxyphenylboronic Acid CAS 51067-38-0
Ibrutinib Intermediate N-2 CAS 330786-24-8
Ibrutinib Intermediate N-3 CAS 330792-70-6
Ibrutinib CAS 936563-96-1

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Litlhaloso tse tšoanang	Ibrutinib mahareng N-2;Ibrutinib Deacryloylpiperidine;Tšilafalo ea Ibrutinib 8;5-(4-Phenoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Tšilafalo
Nomoro ea CAS	330786-24-8
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C17H13N5O
Boima ba Molek'hule	303.32
Melting Point	>262℃(Dec.)
Botenya	1.380±0.06 g/cm3
Sehlopha sa Kotsi	6.1;Chefo
Sehlopha sa ho paka	III
COA & MSDS	E fumaneha
Tšimoloho	Shanghai, China
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Off-White to Khaki Powder
Boitsebiso	HNMR, LC-MS
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Tahlehelo ka ho Omisa	<1.00%
Max a le mong.Ho se hloeke	<1.00%
Litšila ka Kakaretso	<1.00%
Heavy Metals (as Pb)	<20ppm
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Ibrutinib (CAS: 936563-96-1)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.

Melemo:

LBH:

330786-24-8 - Kopo:

3-(4-Phenoxyphenyl) -1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) ke motsoako o sebetsang oa synthetic ho motsoako oa Ibrutinib (CAS: 936563-96-1 ).Ibrutinib ke mofuta oa Bruton tyrosine kinase (BTK) inhibitor, e ka sebelisoa bakeng sa kalafo ea chronic lymphocytic leukemia (CLL) le mantle cell lymphoma (MCL).MCL le CLL ke tsa B-cell non-Hodgkin's lymphoma, eo ho leng thata ho e phekola le ho ipheta habonolo.Lik'hemik'hale tse tloaelehileng tsa immunotherapy ha li na sepheo, hangata li hlaha 3 kapa 4 karabelo e mpe.Li-lymphocyte tsa Ibrutinib le B li ne li ka shebana le BTK e hlokahalang bakeng sa ho thehoa, ho arola, le ho fetisa boitsebiso, ho thibela mosebetsi oa BTK ka mokhoa o sa fetoheng, le ho thibela ho ata ha lisele tsa hlahala le ho phela ka katleho.Ibrutinib e ka kenngoa ka potlako ka mor'a ho tsamaisoa ka molomo, nakong ea 1 ~ 2h e fihla ho bongata ba mali maling, karabelo e mpe ke ea motho a le mong kapa tse peli, ka hona, Ibrutinib e tla fetoha khetho e ncha ea kalafo ea CLL le MCL.