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N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity Featured Image
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Tlhaloso e Khutšoanyane:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8

Ponahalo: Phofo e Bosehla kapa e Batlileng e le Bosehla

Bohloeki: ≥98.0% (HPLC)

Bohareng ba Imatinib Mesylate (CAS: 220127-57-1) ha ho phekoloa Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

Boleng bo Phahameng, Tlhahiso ea Khoebo

Inquiry: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Tlhahiso ea Khoebo ea Imatinib Mesylate le Li-Intermediates tse Amanang:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Litlhaloso tse tšoanang Imatinib Mesylate Mahareng;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Nomoro ea CAS 152460-09-8
Nomoro ea KAtse RF-PI228
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C16H13N5O2
Boima ba Molek'hule 307.31
Melting Point 188.0 ~ 193.0 ℃
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Phofo e Bosehla kapa E Batlileng e le Bosehla
Bohloeki ≥98.0% (HPLC)
Mongobo (KF) ≤0.50%
Litšila ka Kakaretso ≤2.0%
Ho se hloeke ho hoholo ho le Mong ≤1.0%
Masalla ha a tuka ≤0.50%
Litšepe tse boima ≤20ppm
Tekanyetso ea Teko Maemo a Khoebo
Tšebeliso Bohareng ba Imatinib Mesylate (CAS: 220127-57-1)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

1

LBH:

Kopo:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) e nang le boleng bo hodimo.Ke karolo e bohareng ka tloaelo ho kopanngoeng ha Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate ke molek'hule e nyane e thibelang c-Abl protein-tyrosine kinase, E khethehileng haholo bakeng sa BCR-ABL, enzyme e amanang le leukemia e sa foleng ea myelogenous (CML) le mefuta e itseng ea acute lymphoblastic leukemia (ALL).Ketsahalo ea phetoho lipakeng tsa chromosome 9 le 22 e hlahisa Philadelphia chromosome, e ntan'o hlahisa protheine ea Bcr-Abl fusion e nang le ts'ebetso ea aberrant kinase e khothalletsang ho ata ha lisele ka potlako.Imatinib Mesylate e tlama kinase ena ea bohlokoa, e emisa kholo e amanang le CML.Imatinib Mesylate e 'nile ea bontšoa hape ho thibela PDGFR le tyrosine kinases e amanang le c-Kit.Mefuta e nang le Imatinib Mesylate e sebelisitsoe kalafong ea mefuta e fapaneng ea mofetše.

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