Irbesartan CAS 138402-11-6 Purity >99.0% (HPLC) API Factory Antihypertensive
Phepelo ea Moetsi, Bohloeki bo Phahameng, Tlhahiso ea Khoebo
| Lebitso la Lik'hemik'hale | Irbesartan |
| Litlhaloso tse tšoanang | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en- 4-nngwe;2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one |
| Nomoro ea CAS | 138402-11-6 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C25H28N6O |
| Boima ba Molek'hule | 428.54 |
| Botenya | 1.30±0.10 g/cm3 |
| Sollubility ka Metsing | Ha e qhibilihe ka Metsing |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Sebopeho | Crystalline Powder e tšoeu ho isa ho e tšoeu, e qhibiliha hanyane ka joala le ka har'a methylene chloride, hoo e batlang e sa qhibilihe ka metsing. |
| Identification Infrared Absorption | Sekhahla sa IR se ipapisitse le sekhahla se fumanoeng ka Irbesartan RS |
| Boitsebiso 2 | Nako ea ho boloka tlhoro e kholo ea chromatogram ea assay e lumellana le Irbesartan RS. |
| Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) |
| Metsi | <0.50% |
| Litšepe tse boima | <0.002% |
| Masalla a ho Ignition | <0.10% |
| Lintho Tse Amanang | (Ka HPLC) |
| USP Tšilafalo A | <0.20% |
| Tšilafalo efe kapa efe e sa Lemoheng | <0.10% |
| Litšila ka Kakaretso | <0.50% |
| Litšila tsa Organic Volatile | E finyella litlhoko tsa USP |
| Azide e setseng | <10ppm |
| Metsoako e setseng | (Ka GC) |
| Ethanol | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N, N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Ether | <5000ppm |
| Tlhahlobo | 98.0 ~ 102.0% (e baloang ho latela anhydrous) |
| Tekanyetso ea Teko | Maemo a Khoebo;USP Standard |
| Tšebeliso | API;Antihypertensive;Bakeng sa kalafo ea khatello ea mali |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Irbesartan (CAS: C) ke mohanyetsi oa angiotensin II receptor a sebelisoang haholo bakeng sa kalafo ea khatello ea mali.Irbesartan e entsoe ke Sanofi Research (eo hona joale e leng karolo ea Sanofi-Aventis).E rekisoa ka kopanelo ke Sanofi-Aventis le Bristol-Myers Squibb tlasa mabitso a khoebo Aprovel, Karvea, le Avapro.Irbesartan e sebelisoa ho phekola khatello e phahameng ea mali.Avapro e ile ea hlahisoa Jeremane, UK le US bakeng sa khatello ea mali.Joalo ka bahanyetsi bohle ba li-angiotensin II receptor, irbesartan e bontšoa bakeng sa kalafo ea khatello ea mali.Irbesartan e ka boela ea liehisa tsoelo-pele ea nephropathy ea lefu la tsoekere hape e bontšoa bakeng sa ho fokotsa tsoelo-pele ea lefu la renal ho bakuli ba nang le lefu la tsoekere la mofuta oa 2, khatello ea mali le microalbuminuria (ho feta lihora tse 30 mg/24) kapa proteinuria.Irbesartan e ka fokotsa ho nchafatsoa ha motlakase ho myocardium, ka hona ea fokotsa sekhahla sa lefu la bakuli ba nang le khatello ea mali, ke setlhare se sebetsang ka ho fetesisa bakeng sa kalafo ea khatello ea mali le lefu la pelo.
