Irbesartan Intermediate Side Side Chain Hydrochloride CAS 151257-01-1 Purity >99.0% (HPLC) Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride

Synonyms: Irbesartan Side Chain Hydrochloride

CAS: 151257-01-1

Bohloeki: >99.0% (HPLC)

Ponahalo: Bosoeu ho isa ho Phofo e ka bang Bosoeu ea Crystalline

Bohareng ba Irbesartan (CAS: 138402-11-6)

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride
Litlhaloso tse tšoanang	Irbesartan Side Chain Hydrochloride;Tšilafalo ea Irbesartan Lactam;Tšilafalo ea Irbesartan A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-one Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]non-1-en-4-one HCl
Nomoro ea CAS	151257-01-1
Nomoro ea KAtse	RF-PI1894
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C11H18N2O·HCl
Boima ba Molek'hule	230.74
Sollubility ka Metsing	E qhibilihang ka Metsing
Melting Point	235.0~240.0℃
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Bosoeu ba Crystalline Powder e batlileng e ba Bosoeu
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Tahlehelo ka ho Omisa	<0.50%
Masalla a ho Ignition	<0.20%
Litšila ka Kakaretso	<1.00%
Proton NMR Spectrum	E Ikamahanya le Sebopeho
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Irbesartan (CAS: 138402-11-6)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

2-Butyl-1,3-diazaspiro[4.4] non-1-en-4-one Hydrochloride (CAS: 151257-01-1), eo hape e tsejoang e le Irbesartan Side Chain Hydrochloride, ke Intermediate ea Irbesartan (Avapro) (CAS : 138402-11-6).Irbesartan ke angiotensin II receptor inhibitor, angiotensin II receptors e arotsoe ka AT1, AT2, irbesartan e ka thibela AngⅠtransform ho AngII ka khetho e thibelang receptor ea AT1 ea AngII, ka ho khetheha e hanyetsa angiotensin e fetolang enzyme 1 receptor (AT500), receptor ea AT500 ke antagonism. ka linako tse ling ho feta tsa AT2, e ka thibela vasoconstriction le ho lokolloa ha aldosterone ka ho khetha ho thibela AngII e tlamang ka li-receptor tsa AT1 'me ea fella ka phello ea antihypertensive.Sehlahisoa sena ha se thibele angiotensin converting enzyme (ACE), renin, le li-receptor tse ling tsa lihormone, hape ha li hatelle taolo ea khatello ea mali le ho leka-lekana ha liteishene tsa sodium ion.Irbesartan e ka fokotsa ho nchafatsoa ha motlakase ho myocardium, ka hona ea fokotsa sekhahla sa lefu la bakuli ba nang le khatello ea mali, ke setlhare se sebetsang ka ho fetesisa bakeng sa kalafo ea khatello ea mali le lefu la pelo.