Ivabradine Hydrochloride CAS 148849-67-6 Purity >99.5% (HPLC) API Factory
Ruifu Chemical Supply Ivabradine Hydrochloride Intermediates Ka Bohloeki bo Phahameng
Ivabradine Hydrochloride CAS 148849-67-6
4,5-Dimethoxy-1-Cyanobenzocyclobutane CAS 35202-54-1
(1S) -4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride CAS 866783-13-3
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS 73942-87-7
7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one CAS 148870-57-9
3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one CAS 85175-59-3
Lebitso la Lik'hemik'hale | Ivabradine Hydrochloride |
Litlhaloso tse tšoanang | Ivabradine HCl |
Nomoro ea CAS | 148849-67-6 |
Nomoro ea KAtse | RF-PI1812 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C27H36N2O5·HCl |
Boima ba Molek'hule | 505.05 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Boitsebiso | HPLC/UV ea lumellana |
Mokhoa oa Bohloeki / Analysis | >99.5% |
Tahlehelo ka ho Omisa | <1.00% (E omise ka 105 ℃ ka har'a se omisang moea oa motlakase ho fihlela boima bo sa feleng) |
Mongobo | <1.00% |
Masalla a ho Ignition | <0.20% |
Ho Se hloeke ho hoholo ho Leng | <0.50% |
Litšila ka Kakaretso | <0.50% |
Isomer ea mahlo | <0.50% |
Tlhahlobo | >99.5% |
Litšepe tse boima | <20ppm |
Phetoho e khethehileng | +6.5 ° ~ +8.5 ° (ka motheo o omisitsoeng, tharollo ea 1% ho DMSO) |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Ivabradine Hydrochloride (CAS: 148849-67-6),Boitekong ba ho hlahisa mahlahana a angina ntle le liphello tse sa batleheng tsa inotropic le hypotensive tse amanang le b-adrenergic blockers le calcium channel blockers, sehlopha se secha sa metsoako e fokotsang pelo e sebetsang ka ho khetheha ho node ea sinoatrial (SA) e 'nile ea hlahlojoa.Mahlahana ana a bradycardic a sebelisana ka kotloloho le sele ea pacemaking ea node ea SA le hyperpolarization- activated If the primary pacemaking current.Ivabradine e fetohile e le inhibitor e itseng ea Haeba hona joale ka ho kopana le li-channel tsa f-ka lehlakoreng la intracellular la lera la plasma.Ka lebaka leo, Ivabradine e fokotsa lebelo la diastolic depolarization le fokotsa lebelo la pelo.E amohetsoe bakeng sa phekolo ea angina e tsitsitseng e sa foleng 'me e fana ka mokhoa o mong o sebetsang ho bakuli ba nang le contraindication kapa ho se mamelle ha b-blockers.Tlhahlobo e boetse e tsoela pele bakeng sa phekolo e ka bang teng ea lefu la pelo ea ischemic.