L-Serine CAS 56-45-1 (H-Ser-OH) Assay 98.5~101.0% Factory High Quality
Shanghai Ruifu Chemical Co., Ltd. ke mofani ea ka sehloohong oa L-Serine (H-Ser-OH; Ser e khutsufalitsoeng kapa S) (CAS: 56-45-1) e nang le boleng bo phahameng.E le e mong oa barekisi ba kholo ka ho fetisisa ba li-amino acid Chaena, Ruifu Chemical e fana ka li-amino acid tse finyellang litekanyetso tsa AJI, USP, EP, JP le FCC.Re ka fana ka COA, phano ea lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Haeba u thahasella L-Serine,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | L-Serine |
| Litlhaloso tse tšoanang | H-Ser-OH;L-Ser;Kgutsufatso Ser kapa S;(-)-Serine;Serine;Laevo-Serine;(S)-Serine;L-2-Amino-3-Hydroxypropionic Acid;(S) -2-Amino-3-Hydroxypropionic Acid;(S) -α-Amino-β-Hydroxypropionic Acid;L-3-Hydroxy-2-Aminopropionic Acid;3-Hydroxy-L-Alanine;β-Hydroxy-L-Alanine |
| Boemo ba Setoko | Ka Setokong, Bokhoni ba Tlhahiso Lithane tse 500 ka Selemo |
| Nomoro ea CAS | 56-45-1 |
| Foromo ea limolek'hule | C3H7NO3 |
| Boima ba Molek'hule | 105.09 |
| Melting Point | 222℃(Dec.) (lit.) |
| Botenya | 1.6 |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing, e batla e pepenene |
| Solubility | E qhibiliha ka bolokolohi ho Formic Acid.Ha e khone ho qhibiliha ka har'a Ethanol le Ether.E qhibiliha ka Dilute Hydrochloric Acid |
| Mocheso oa polokelo. | E tiisitsoe ka Dry, Store ka Mocheso oa Kamore |
| COA & MSDS | E fumaneha |
| Karolelano | Li-Amino Acids le Li-Derivatives |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Likristale tse tšoeu kapa phofo ea Crystalline | E lumellana |
| Boitsebiso | Infrared Absorption Spectrum | E lumellana |
| Potoloho e Khethehileng [α]20/D | +14.4° ho ea ho +15.5° (C=10, 2N HCl) | -33.8° |
| Boemo ba Tharollo (Transmittance) | E hlakile ebile ha e na 'Mala ≥98.0% | 98.6% |
| Chloride (Cl) | ≤0.020% | <0.020% |
| Sulfate (SO4) | ≤0.020% | <0.020% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Tshipi (Fe) | ≤10ppm | <10ppm |
| Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Li-amino acid tse ling | Chromatographically Ha e Fumanehe | E lumellana |
| Tahlehelo ka ho Omisa | ≤0.20% (ho 105 ℃, lihora tse 3) | 0.15% |
| Residue on Ignition (Sulfated) | ≤0.10% | 0.06% |
| Tlhahlobo | 98.5 ho isa ho 101.0% (Titration: Omisitsoeng Motheo) | 99.7% |
| Tlhahlobo ea pH | 5.2 ho isa ho 6.2 (1.0g ho 10ml ea H2O) | 5.5 |
| Litšila tsa Organic Volatile | E Kopana le Litlhoko | E lumellana |
| Tšimoloho | Mohloli oo e seng oa Liphoofolo | E lumellana |
| Metsoako e setseng | E lumellana | E lumellana |
| Qetello | E kopana le AJI97, EP, USP, JP Litlhaloso tsa Teko | |
| Shelf Life | Likhoeli tse 24 ho tloha ka Letsatsi la Tlhahiso haeba li bolokiloe hantle | |
| Lisebelisoa tse ka Sehloohong | Lisebelisoa tsa Lijo;Meriana ea meriana;Tlatsetso ea Phepo;etc. | |
Sephutheloana: Botlolo ea Fluorinated, 25kg/bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o pholileng hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
JP16
L-Serine, ha e omisitsoe, ha e na ka tlase ho 98.5% le ho feta 101.0% ea C3H7NO3.
Tlhaloso L-Serine e hlaha e le likristale tse tšoeu kapa phofo ea crystalline.E na le tatso e monate e nyane.E qhibiliha ka bolokolohi metsing le ka asiti ea formic, 'me e batla e sa qhibilihe ka har'a ethanol (99.5).E qhibiliha ka 2 mol/L hydrochloric acid TS.
Identification Hlalosa hore na infrared absorption spectrum ea L-Serine e laetsoe ka mokhoa oa potassium bromide disk tlas'a Infrared Spectrophotometry <2.25>, 'me u bapise spectrum le Reference Spectrum: ka bobeli li bontša matla a tšoanang a ho monya ka linomoro tse tšoanang tsa maqhubu.
Potoloho ea mahlo <2.49> [a]20D: +14.0°~+16.0°(Kamora ho omisa, 2.5 g, 2 mol/L hydrochloric acid TS, 25 mL, 100 mm).
pH <2.54> PH ea tharollo e lokiselitsoeng ka ho qhibiliha 1.0 g ea L-Serine ka 10 mL ea metsi e pakeng tsa 5.2 le 6.2.
Bohloeki (1) Ho hlaka le 'mala oa tharollo-Hlakola 1.0 g ea L-Serine ka 10 mL ea metsi: tharollo e hlakile ebile ha e na mebala.
(2) Chloride <1.03> -Etsa teko ka 0.5 g ea L-Serine.Lokisetsa tharollo ea taolo ka 0.30 mL ea 0.01mol/L hydrochloric acid VS (e seng ho feta 0.021%).
(3) Sulfate <1.14> Etsa tlhahlobo ka 0.6 g ea L-Serine.Lokisetsa tharollo ea taolo ka 0.35 mL ea 0.005mol/L sulfuric acid VS (e seng ho feta 0.028%).
(4) Ammonium <1.02> -Etsa tlhahlobo ka 0.25 g ea L-Serine.Lokisetsa tharollo ea taolo ka 5.0 mL ea Standard Ammonium Solution (e seng ho feta 0.02%).
(5) Metals e boima <1.07> Tsoela pele ka 2.0 g ea L-Serine ho ea ka Mokhoa oa 1, 'me u etse tlhahlobo.Lokisetsa tharollo ea taolo ka 2.0 mL ea Standard Lead Solution (eseng ho feta 10 ppm).
(6) Iron <1.10> Lokisetsa tharollo ea teko ka 1.0 g ea L-Serine ho ea ka Mokhoa oa 1, 'me u etse tlhahlobo ho ea ka Mokhoa oa A. Lokisetsa tharollo ea taolo ka 1.0mL ea Standard Iron Solution (e seng ho feta 10 ppm) .
(7) Lintho Tse Amanang - Hlakola 0.10 g ea L-Serine ka 10mL ea metsi, 'me u sebelise tharollo ena e le mohlala oa tharollo.Pipete 1 ml ea tharollo ea sampole, eketsa metsi ho etsa 10 ml hantle.Pipet 1 mL ea tharollo ena, eketsa metsi ho etsa hantle 50 mL, 'me u sebelise tharollo ena e le tharollo e tloaelehileng.Etsa tlhahlobo ka litharollo tsena joalokaha ho laetsoe tlas'a Thin-layer Chromatography<2.03>.Spot 5mLeachofthesample ea tharollo le tharollo e tloaelehileng poleiting ea silica gel forthin-layer chromatography.Ebe u ntshetsa pele ka motsoako oa 1-butanol, metsi le acetic acid (100) (3:1:1) ho isa bohole ba 10 cm, 'me u omise poleiti ka 809C metsotso e 30.Tharollo ea Sprayevenly ea ninhydrinin motsoako oa methanol andacetic acid (100) (97:3) (1 ho 100) poleiting, le mocheso ho 80 ℃ metsotso e 10: sebaka se seng ntle le sebaka se ka sehloohong se fumanoeng ho tsoa ho sampuli ea tharollo ha se joalo. e matla hofeta letheba ho tsoa ho tharollo e tloaelehileng.
Tahlehelo ha o Omisa <2.41> Ha e fete 0.3%(1 g, 105℃, lihora tse 3).
Masalla a ho Ignition <2.44> Ha a fete 0.1%(1 g).
Assay Beha boima bo nepahetseng ka 0.11 g ea L-Serine, e neng e omisitsoe pele, qhala ka 3 mL ea formic acid, eketsa 50 mL ea acetic acid (100), le titrate <2.50> ka 0.1 mol/L perchloric acid VS (potentiometric titration).Etsa qeto e se nang letho ka mokhoa o ts'oanang, 'me u etse tokiso e hlokahalang.
ML ka 'ngoe ea 0.1 mol/L perchloric acid VS＝10.51 mg ea C3H7NO3
Lijana le polokelo Lijana-Tight lijana.
USP39-NF34
TLHALOSO L-Serine e na le NLT 98.5% le NMT 101.5% ea L-serine (C3H7NO3), e baloang ka mokhoa o omisitsoeng.
TS'ELISO TS'OANE
A. HO AMOHELA INFORARED <197K>
TLHOKOMELO
MOKHOAOA
Mohlala: 100mg ea Serine
Sekheo: Kopanya 3mL ea formic acid le 50mL ea glacial acetic acid.
Sistimi ea Titrimetric
(Sheba Titrimetry <541>)
Mokhoa: Titration e tobileng
Titrant: 0.1 N perchloric acid VS
Ho lemoha lintlha tsa ho qetela: Potentiometric
Tlhahlobo: Qhala Mohlala ho 3mL ea asiti ea formic le 50mL ea glacial acetic acid.Titrate le Titrant.
Etsa boitlamo bo se nang letho.
Bala liperesente tsa serine (C3H7NO3) sampoleng e nkiloeng:
Sephetho = {[(VS-VB) xNxF]/W} x100
VS= Bophahamo ba Titrant bo jeoang ke Mohlala (mL)
VB = Bophahamo ba Titrant bo jeoang ke Blank (mL)
N= tloaelo ea 'nete ea Titrant (mEq/mL)
F= ntlha e lekanang, 105.1mg/mEq
W= Boima ba mohlala (mg)
Mekhoa ea ho amohela: 98.5% ~ 101.5% ka mokhoa o omisitsoeng
LITŠILA
HO HLAHALA HO HLAHALA <281>: NMT 0.1%
CHLORIDEAND SULFATE, Chloride <221>
Tharollo e tloaelehileng: 0.50mL ea 0.020 N hydrochloric acid
Mohlala: 0.73g ea Serine
Maemo a kamohelo: NMT 0.05%
CHLORIDEAND SULFATE, Sulfate <221>
Tharollo e tloaelehileng: 0.10mL ea 0.020 N sulfuric acid
Mohlala: 0.33g ea Serine
Maemo a kamohelo: NMT 0.03%
IRON <241>: NMT 30ppm
Hlakola tse latelang:
LINTLHA TSE BOHLOKO, Mokhoa oa I <231>: NMT 15ppm (Official 1-Jan-201)
TS'OANELO MAKANYANA
Tharollo ea ho tšoaneleha ha tsamaiso: 0.4mg/mL e 'ngoe le e 'ngoe ea USP L-Serine RS le USP L-Methionine RS ka 0.1 N hydrochloric acid
Tharollo e tloaelehileng: 0.05mg / mL ea USP L-Serine RS ka 0.1 N hydrochloric acid.[HLOKOMELA-Tharollo ena e na le mohopolo o lekanang le hoo e ka bang 0.5% ea tharollo ea Mohlala.]
Tharollo ea mohlala: 10mg / mL ea Serine ka 0.1 N hydrochloric acid
Sisteme ea Chromatographic Sheba Chromatography <621>, Thin-Layer Chromatography.)
Mokhoa: TLC
Adsorbent: 0.25-mm lera la chromatographic silica gel motsoako
Bophahamo ba kopo: 5μL
Ho ntshetsa pele tsamaiso ya solvent: Butyl alcohol, glacial acebutyl alcohol le 2N acetic acid (95:5)
Ho nepahala ha sistimi
Litlhoko tsa ho tšoaneleha: Chromatogram ea tharollo ea ts'ebetso ea Sistimi e bonts'a matheba a mabeli a arohaneng ka ho hlaka.
Tlhahlobo
Mehlala: Tharollo ea ho tšoaneleha ha Sisteme, Tharollo e tloaelehileng, le Tharollo ea Mohlala.
Kamora ho omisa poleiti ka moea, fafatsa ka spray reagent, 'me u futhumale lipakeng tsa 100° le 105° metsotso e 15.Hlahloba poleiti tlas'a khanya e tšoeu.
Mokhoa oa ho amohela: Sebaka sefe kapa sefe sa bobeli sa tharollo ea Sample ha se seholo kapa se matla ho feta sebaka sa mantlha sa tharollo ea Maemo.
Litšila tsa motho ka mong: NMT 0.5%
Kakaretso ea litšila: NMT 2.0%
LITEKO TSEKO
PHETOHO EA MAIKUTLO, Phapanyetsano e Khethehileng <781S>
Mohlala oa tharollo: 100mg/mL ho 2N hydrochloric acid
Mekhoa ea ho amohela: +14.0 ° ho ea ho +15.6 °
HO OMETSA LOSSON <731>: Omisa sampole ho 105℃ bakeng sa 3 h: e lahleheloa ke NMT 0.2% ea boima ba eona.
KEKELETSO LIHLOKO
ACKAGINGAND STORAGE: Boloka ka lijaneng tse koetsoeng hantle.
USP REFERENCE LITEKELO <11>
USP L-Methionine RS
USP L-Serine RS
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
| Matšoao a Kotsi | Xi - Ea halefisang |
| Likhoutu tsa Kotsi | 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo. |
| Tlhaloso ea Tšireletseho | S24/25 - Qoba ho kopana le letlalo le mahlo. S36 - Apara liaparo tse loketseng tsa tšireletso. S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. |
| WGK Jeremane | 3 |
| RTECS | VT8100000 |
| F | 3 |
| TSCA | Ee |
| Khoutu ea HS | 2922509099 |
L-Serine (H-Ser-OH; E khutsufalitsoeng Ser kapa S) (CAS: 56-45-1) ke amino acid, ke e 'ngoe ea li-amino acid tsa proteinogenic.Li-codon tsa eona tsa liphatsa tsa lefutso ke UCU, UCC, UCA, UCG, AGU le AGC.Ka lebaka la sehlopha sa hydroxyl, serine e khetholloa e le polar amino acid.
Mosebetsi le Tšebeliso ea L-Serine Cas 56-45-1
1. L-Serine e sebelisoa e le reagent ea biochemical le li-additives tsa lijo;E sebelisoa lipatlisisong tsa biochemical, mokhatlo o hlophisitsoeng oa setso, moriana o sebelisetsoang li-amino acid ho moriana oa phepo.
2. L-Serine e sebelisoa tšimong ea meriana, L-Serine e sebelisoa haholo ho configure moloko oa boraro motsoako oa amino acid infusion le nutritionalbsupplements, le bakeng sa ho qapa mefuta e fapaneng ya silika amino acid derivatives, tse kang pelo, kankere, AIDS le liphatsa tsa lefutso. boenjiniere ba lithethefatsi tse ncha le li-amino acid tse ling tse sirelelitsoeng.Tšimo ea lijo le seno, L-Serine e ka sebelisoa ho lino tsa lipapali, lino tsa amino acid.Tšimo ea phepelo, L-Serine e ka sebelisoa ho fepa liphoofolo, ho khothaletsa kholo le nts'etsopele ea liphoofolo;
3. L-Serine e sebelisoa e le tlatsetso ea phepo e nepahetseng, litlolong e le setlolo sa phepo ea letlalo.
4. E fumaneha molemong oa lipatlisiso tsa biochemical le phepo e nepahetseng, empa hape e ka sebelisoa e le lisebelisoa tsa maiketsetso tsa serine.
5. L-Serine e na le mefuta e mengata ea tšebeliso ea meriana.Serine e khothalletsa metabolism ea mafura le mafura acid 'me e thusa ho boloka sesole sa' mele.
6. L-Serine e boetse e sebelisoa e le tlatsetso ea lijo moo e ka thusang ho ntlafatsa ts'ebetso ea mohopolo le lihlahisoa tsa tlhokomelo ea botho moo e thusang ka tlhahiso ea lisele tse ncha tsa letlalo.
7. L-Serine e 'nile ea sebelisoa ha ho lokisetsoa Tris-BSAN buffer bakeng sa homogenization.E boetse e sebelisoa bakeng sa tlhahlobo ea bongata ba ho ntšoa ha polypeptides morotong o tloaelehileng.
8. L-Serine e sebelisoa ha ho etsoa li-purines le pyrimidines e le li-antibacterial / antifungal agents, hammoho le ho sebetsa e le motsoako oa protheine.
9. L-Serine e khetholloa e le amino acid e seng ea bohlokoa.E sebelisoa e le karolo ea mecha ea litaba ea setso sa lisele le lisebelisoa tse tala bakeng sa biomanufacture ea khoebo ea liprotheine tse nchafatsang tsa kalafo le li-antibodies tsa monoclonal.
10. L-Serine ka phosphorylation-hydroxy derivative e ka ntšoa ka mor'a mesebetsi ea bohlokoa ea 'mele ea P serine ke karolo e kholo ea phospholipids;
11. L-Serine e nang le pH e tsitsitseng ea bohlokoa ba karolo ea marotholi a mahlo, marotholi a mahlo le a sa thabiseng;
12. L-Serine ke ntho ea bohlokoa ea tlhaho ea tlhaho (NMF) ke e 'ngoe ea stratum corneum ho boloka karolo e ka sehloohong ea metsi, L-Serine ke senotlolo sa li-additives tse tsoetseng pele tsa litlolo.
