Lasofoxifene Tartrate CAS 190791-29-8 Chiral Purity ≥99.0% Purity ≥98.0% (HPLC) API High Purity
Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Lasofoxifene Tartrate
CAS: 190791-29-8
Lasofoxifene Tartrate (CAS: 190791-29-8) kalafo ea Postmenopausal Osteoporosis
Lebitso la Lik'hemik'hale | Lasofoxifene tartrate |
Litlhaloso tse tšoanang | (5R,6S) -5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl) ethoxy]phenyl] -2-naphthalenol Tartrate Oporia |
Nomoro ea CAS | 190791-29-8 |
Nomoro ea KAtse | RF-API20 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C28H31NO2.ClH |
Boima ba Molek'hule | 450.019 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
Mongobo (KF) | ≤0.50% |
Litšepe tse boima | ≤20ppm |
Chiral Purity | ≥99.0% |
Mokhoa oa Bohloeki / Analysis | ≥98.0% (HPLC) |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.50% |
Tekanyetso ea Teko | Pharmacopoeia ea Chaena (CP);Maemo a Khoebo |
Tšebeliso | Motsoako o sebetsang oa Pharmaceutical (API);Osteoporosis ea Postmenopausal |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Lasofoxifene Tartrate (CAS: 190791-29-8) e nang le boleng bo phahameng.
Lasofoxifene Tartrate ke moloko oa boraro, e seng steroidal selective estrogen receptor modulator (SERM).E tlama ka mokhoa o ikhethileng ho ERalpha ea motho ka boleng ba IC50 ba 1.5 nM mme e thibela tahlehelo ea masapo ho likhoto tse entsoeng ka mahe a linotsi.Lithutong tsa bongaka tsa postmenopausal osteoporosis, 0.5 mg / letsatsi lasofoxifene e ne e amahanngoa le likotsi tse fokotsehileng tsa ho robeha ha mokokotlo le mokokotlo oa mokokotlo, kankere ea matsoele ea ER-positive, lefu la pelo le stroke empa kotsi e eketsehileng ea liketsahalo tsa venous thromboembolic.Lasofoxifene e boetse e bontšitsoe hore e sebetsa e le agonist e fapaneng ho CB2 cannabinoid receptor, e bontšang bokhoni ba eona ba ho khutlisetsoa hape e le phekolo bakeng sa matšoao ao CB2 e leng sepheo sa eona.