Lenvatinib Mesylate Intermediate CAS 205448-65-3 Bohloeki >98.0% (HPLC) Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Bohloeki: >98.0% (HPLC)

Ponahalo: Bosoeu bo Bosoeu ho isa Bosehla

Bohareng ba Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Ka Bohloeki bo Phahameng
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Litlhaloso tse tšoanang	1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;Lenvatinib ea Hare 3
Nomoro ea CAS	205448-65-3
Nomoro ea KAtse	RF-PI1973
Boemo ba Setoko	Ka Setokong, Bokhoni ba Tlhahiso 50 MT / Selemo
Foromo ea limolek'hule	C12H11NO4
Boima ba Molek'hule	233.22
Ntlha e belang	421.0±45.0℃
Botenya	1.267±0.060 g/cm3
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Tletseng-Bosoeu ho isa ho Bosehla
Mokhoa oa Bohloeki / Analysis	>98.0% (HPLC)
Tahlehelo ka ho Omisa	<1.00%
Masalla a ho Ignition	<0.50%
Litšila ka Kakaretso	<2.00%
H-NMR	E Ikamahanya le Sebopeho
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Mekhatlo ea Meriana

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) ke bohareng ba Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, e rekisoang ka lebitso la Lenvima har'a tse ling, ke moriana o thibelang mofetše bakeng sa ho alafa mefuta e itseng ea mofetše oa qoqotho le mefetše e meng hape.E entsoe ke Eisai Co. 'me e sebetsa e le multiple kinase inhibitor khahlanong le VEGFR1, VEGFR2 le VEGFR3 kinases.Lenvatinib e amohetsoe (ho tloha 2015) bakeng sa kalafo ea mofets'e oa qoqotho o fapaneng oo e ka bang o ipheta-pheta kapa oa metastatic, o tsoelang pele, o sa arabeleng kalafo ka radioactive iodine (radioiodine).Ka May 2016, US Food and Drug Administration (FDA) e ile ea e amohela (hammoho le everolimus) bakeng sa phekolo ea kankere ea kankere ea renal e tsoetseng pele ka mor'a phekolo e le 'ngoe ea pele ea anti-angiogenic.Setlhare sena se boetse se amohetsoe US le European Union bakeng sa kankere ea sebete ea hepatocellular e ke keng ea tlosoa ka ho buuoa ho bakuli ba sa kang ba fumana phekolo ea kankere ka molomo kapa ka ente.