Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II High Quality
Fana ka Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Letrozole
CAS: 112809-51-5
Aromatase Inhibitor II
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Letrozole |
Litlhaloso tse tšoanang | CGS-20267;Femara |
Nomoro ea CAS | 112809-51-5 |
Nomoro ea KAtse | RF-API86 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C17H11N5 |
Boima ba Molek'hule | 285.3 |
Melting Point | 181.0 ho isa ho 183.0 ℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Solubility | E qhibiliha hanyenyane ka har'a Dichloromethane, e Hanyenyane Hanyenyane ka Ethanol 'me ha e khone ho qhibiliha ka metsing. |
Boitsebiso ba IR | Spectrum ea sampole e lumellana le ea referense standard |
Boitsebiso ba HPLC | Nako ea ho boloka sampole ea teko e tsamaisana le ea maemo a referense |
Litaba tsa Metsi (ka KF) | ≤0.30% |
Masalla a ho Ignition | ≤0.10% |
Lintho Tse Amanang | |
Lintho tse amanang A | ≤0.30% |
Lintho Tse Amanang le B | ≤0.20% |
Tšilafalo efe kapa efe e sa Boleloeng | ≤0.10% |
Kakaretso ea Litšila tse sa Boleloeng | ≤0.30% |
Litšila ka Kakaretso | ≤0.50% |
Metsoako e setseng | |
Ethyl Acetate | ≤0.50% |
Methanol | ≤0.30% |
Ethanol | ≤0.50% |
DMF | ≤0.088% |
Litšepe tse boima | ≤10ppm |
Tlhahlobo | 98.0% ~ 102.0% (motheong oa anhydrous) |
Shelf Life | Likhoeli tse 24 |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API, Aromatase Inhibitor II |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Letrozole (CAS 112809-51-5) ke karolo ea moloko o mocha oa li-inhibitors tsa aromatase tse khethiloeng haholo 'me ke motsoako o entsoeng ka maiketsetso oa benzotriazole.Letrozole e thibela aromatase ho theola maemo a estrogen, kahoo e thibela estrogen ho susumetsa kholo ea hlahala.Ts'ebetso ea eona ea in vivo e matla ka makhetlo a 150-250 ho feta ea moloko oa pele oa aromatase inhibitor Amarante.Kaha e khetha haholo, e ke ke ea ama glucocorticoid, mineralocorticoid le mesebetsi ea qoqotho;esita le ka litekanyetso tse phahameng, e ke ke ea e-ba le liphello tse thibelang li-adrenal corticosteroid secretion, e fanang ka index e phahameng ea phekolo.Letrozole ha e na chefo e patehileng ho litsamaiso leha e le life tsa 'mele le litho tse reretsoeng, ha e na mutagenicity le liphello tsa kankere, e na le litla-morao tse fokolang tse chefo, e mamelloa hantle,' me e na le liphello tse matla tsa anticancer ho feta tse ling tsa aromatase inhibitors le lithethefatsi tsa antiestrogen.Letrozole e loketse bakuli ba tsoetseng pele ba kankere ea matsoele ba postmenopausal ba sa kang ba arabela kalafo ea khatello ea estrogen le kalafo ea pele ea mofetše oa matsoele.E sebelisoa ho alafa bakuli ba postmenopausal ba nang le mofetše oa matsoele o tsoetseng pele 'me e sebetsa e le kalafo ea bobeli ho latela kalafo e sa atleheng ea antiestrogen.