Linagliptin CAS 668270-12-0 Purity ≥99.0% (HPLC) Feme
Phepelo ea Moetsi, Bohloeki bo Phahameng, Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: Linagliptin
CAS: 668270-12-0
Lebitso la Lik'hemik'hale | Linagliptin |
Litlhaloso tse tšoanang | BI-1356;8-[(3R)-3-Amino-1-piperidinyl] -7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H -purine-2,6-dione |
Nomoro ea CAS | 668270-12-0 |
Nomoro ea KAtse | RF-API105 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C25H28N8O2 |
Boima ba Molek'hule | 472.54 |
Melting Point | 197.0 ho isa ho 200.0 ℃ |
Solubility | E qhibiliha ka DMSO |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
NMR | E Lumellanang le Sebopeho |
Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.10% |
Litšepe tse boima | ≤10ppm |
Lintho Tse Amanang | |
Tšilafalo e le Mong | ≤0.50% |
Litšila ka Kakaretso | ≤1.0% |
Isomer | ≤0.15% |
Metsoako e setseng | |
Methanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Linagliptin (CAS: 668270-12-0) ke inhibitor ea DPP-4 e entsoeng ke Boehringer Ingelheim bakeng sa phekolo ea lefu la tsoekere la mofuta oa II.Litšobotsi tse peli tsa pharmacological tse khethollang linagliptin ho li-inhibitors tse ling tsa DPP-4 ke hore e na le profil ea pharmacokinetic e sa lekanyetsoang mme ha e felisoe haholo ke sistimi ea renal.Linagliptin (hang ka letsatsi) e amohetsoe ke US FDA ka la 2 Motšeanong 2011 bakeng sa kalafo ea lefu la tsoekere la mofuta oa II.E ntse e rekisoa ke Boehringer Ingelheim le Lilly.Linagliptin, e rekisoang tlas'a lebitso la Tradjenta har'a ba bang.E sebelisoa hammoho le boikoetliso le lijo.