Luliconazole CAS 187164-19-8 Purity ≥99.0% HPLC Factory API High Quality
Fana ka Luliconazole le Li-Intermediate tse Amanang
Luliconazole CAS 187164-19-8
(1-Imidazolyl)acetonitrile CAS 98873-55-3
(S) -2,4-Dichloro-α-(Chloromethyl)benzyl Alcohol CAS 126534-31-4
Lebitso la Lik'hemik'hale | Luliconazole |
Litlhaloso tse tšoanang | (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile;NND 502 |
Nomoro ea CAS | 187164-19-8 |
Nomoro ea KAtse | RF-API110 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C14H9Cl2N3S2 |
Boima ba Molek'hule | 354.27 |
Melting Point | 150.0 ho isa ho 154.0 ℃ |
Phetoho e khethehileng [a]20/D | -48.0° ho ya ho -53.0° (C=1, DMF) |
Solubility | Ha e qhibilihe ka metsing;E qhibiliha ka har'a acetone;E qhibiliha hanyenyane ka Methanol |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Bosoeu bo Bosoeu ho isa ho Bosehla ba Crystalline Powder |
Boitsebiso ba IR | Sekhahla sa infrared sa sampole se lokela ho lumellana le sa maemo a referense |
Boitsebiso ba HPLC | Nako ea ho boloka tlhōrō e kholo ea tharollo ea mohlala e lokela ho lumellana le ea tharollo e tloaelehileng joalokaha e fumanoe tekong |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšepe tse boima (Pb) | ≤20ppm |
Lintho Tse Amanang | |
Tšilafalo efe kapa efe ea Motho ka Mong | ≤0.20% |
Litšila ka Kakaretso | ≤0.50% |
Metsoako e setseng | |
Methanol | ≤3000ppm |
Acetonitrile | ≤410ppm |
Dichloromethane | ≤600ppm |
N-Hexane | ≤290ppm |
Ethyl Acetate | ≤5000ppm |
Tetrahydrofuran | ≤720ppm |
Methyl tert-Butyl Ether | ≤5000ppm |
N-Heptane | ≤5000ppm |
Triethylamine | ≤320ppm |
Dimethyl Sulfoxide | ≤5000ppm |
Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) (ka motheo o omisitsoeng) |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Mekhatlo ea Meriana |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Luliconazole (CAS: 187164-19-8) ke sebolaya-mafu sa imidazole se ka sehloohong se nang le mahlahahlaha a mangata le a matla a antifungal.Luliconazole ke mofuta oa analogue ea lanoconazole.E ka kena-kenana le sebopeho sa lerako la fungal le kholo ea fungal ka ho fokotsa maemo a ergosterol ka ho thibela tšebetso ea lanosterol demethylase.Ntle le ho sebelisoa bakeng sa kalafo ea leoto la moatlelete, jock itch le ringworm, e boetse e ntlafalitsoe bakeng sa kalafo ea onychomycosis (nail fungus) mme joale e se e kene sehlopheng sa III sa bongaka.Sehlahisoa sena qalong se entsoe ke Mokhatlo oa Japane oa chefo e bolaeang likokoanyana (NihonNohyaku Co., Ltd.).Ka Pulungoana 2013, FDA e amohetse tranelate ea luliconazole ea 1% bakeng sa ho kena 'marakeng bakeng sa kalafo ea mantlha ea leoto la moatlelete oa li-interdigital, jock itch le ringworm ka lebitso la khoebo e leng Luzu mme ea qala ho kena' marakeng Amerika Leboea.Ho tloha ka Mmesa 2005, luliconazole e ne e amohetsoe ho kena 'marakeng Japane tlasa lebitso la khoebo la Lulicon.Ka Pherekhong 2010 le Phuptjane 2012, e ile ea amoheloa bakeng sa ho bapatsa India le China, ka ho latellana.