Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity >99.0% (HPLC) Nintedanib Esylate Intermediate Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Methyl 2-Oxoindoline-6-Carboxylate

CAS: 14192-26-8

Bohloeki: >99.0% (HPLC)

Ponahalo: Bosehla bo Khanyang ho ea ho Phofo e Sootho

Bohareng ba Nintedanib Esylate (CAS: 656247-18-6) kalafong ea mofets'e o seng o monyane oa kankere ea matšoafo le idiopathic pulmonary fibrosis (IPF)

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

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Lintlha tsa Sehlahisoa

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Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) e nang le boleng bo phahameng, tlhahiso ea khoebo.

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Methyl 2-Oxoindoline-6-Carboxylate
Litlhaloso tse tšoanang	2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate
Nomoro ea CAS	14192-26-8
Nomoro ea KAtse	RF-PI1524
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C10H9NO3
Boima ba Molek'hule	191.19
Melting Point	184.0 ~ 190.0 ℃
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Bosehla bo Khanyang ho isa ho Phofo e Sootho
1 H NMR Spectrum	E Lumellanang le Sebopeho
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Tahlehelo ka ho Omisa	<1.00%
Litšila ka Kakaretso	<1.00%
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Nintedanib Esylate (CAS: 656247-18-6)

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Tsela ea Synthetic

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.

Melemo:

LBH:

Kopo:

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) ke sebaka se bohareng se sebelisetsoang ho lokisetsa Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate ke inhibitor e matla, ea molomo e meraro ea angiokinase e entsoeng ke Boehringer Ingelheim e lebisang litsela tsa proangiogenic le pro-fibrotic tse kentsoeng ke vascular endothelial growth factor receptor, fibroblast growth factor receptor le plateletderederved growth factor receptor malapa, hammoho le Src le Flt-3. kinase.Nintedanib Esylate e ile ea amoheloa bakeng sa phekolo ea idiopathic pulmonary fibrosis (IPF), boemo boo ho bona matšoafo a ntseng a senyeha butle-butle ha nako e ntse e ea, ke US FDA ka October 2014 le EMA ka January 2015. FDA e fane ka nintedanib esylate kapele-pele. , tlhahlobo ea bohlokoa, sehlahisoa sa likhutsana, le mabitso a katleho.E boetse e amohetsoe ke EMA ka Pulungoana 2014 bakeng sa kalafo ea mofetše oa matšoafo oa sele e seng nyane hammoho le docetaxel kamora chemotherapy ea pele.