Molnupiravir (EIDD-2801) CAS 2349386-89-4 COVID-19 API Boleng bo Phahameng
Phepelo ea Khoebo ea Molnupiravir le Litšehare tse Amanang le Boleng bo Phahameng
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Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Lebitso la Lik'hemik'hale | Molnupiravir (EIDD-2801) |
| Litlhaloso tse tšoanang | MK-4482;β-D-N4-Hydroxycytidine-5'-isopropyl ester;((2R,3S,4R,5R)-3,4-dihydroxy-5-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2 -yl) methyl isobutyrate |
| Nomoro ea CAS | 2349386-89-4 |
| Nomoro ea KAtse | RF-API97 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | C13H19N3O7 |
| Boima ba Molek'hule | 329.31 |
| Solubility | E qhibiliha ka DMSO |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
| Boitsebiso ba IR | Mohlala oa Spectrum o lumellana le maemo a referense |
| Boitsebiso ba HPLC | Nako ea ho boloka tlhōrō e kholo ea tharollo ea mohlala e lumellana le ea tharollo e tloaelehileng |
| Lintho Tse Amanang | |
| Tšilafalo A | ≤0.15% |
| Tšilafalo B | ≤0.15% |
| Tšilafalo efe kapa efe e sa Boleloeng | ≤0.15% |
| Kakaretso ea Litšila tse sa Boleloeng | ≤0.30% |
| Litšila ka Kakaretso | ≤0.50% |
| Metsoako e setseng | |
| N-Heptane | ≤5000ppm |
| Ethanol | ≤5000ppm |
| Acetate ea isopropyl | ≤5000ppm |
| Acetonitrile | ≤410ppm |
| Methylene dichloride | ≤600ppm |
| Acetone | ≤5000ppm |
| Isopropanol | ≤5000ppm |
| Litaba tsa Metsi (KF) | ≤0.50% |
| Masalla a ho Ignition | ≤0.10% |
| Ho potoloha ha Optical | -7.5° ho ya ho -9.5° (C=0.5, Methanol) |
| Litšepe tse boima | ≤10ppm |
| Mokhoa oa Bohloeki / Analysis | ≥99.5% (230nm) |
| Mokhoa oa ho hlahloba / oa ho hlahloba | 98.0% ~ 102.0% (HPLC ka motheo o omisitsoeng) |
| Shelf Life | Likhoeli tse 24 |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API, Molnupiravir (EIDD-2801) COVID-19 Inhibitor |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Molnupiravir (EIDD-2801, MK-4482) ke prodrug ea molomo ea bioavailable ea ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) e nang le ts'ebetso e pharaletseng ea antiviral khahlanong le SARS-CoV-2, MERS-CoV, SARS-CoV, le moemeli ea bakang COVID-19.Molnupiravir e rekisoa tlasa lebitso la Lagevrio mme ka kakaretso e le emorivir.Molnupiravir e bonts'itsoe ho ntlafatsa ts'ebetso ea matšoafo, ho fokotsa boima ba 'mele le ho fokotsa bongata ba kokoana-hloko matšoafong.Ntle le ts'ebetso e khahlano le li-coronavirus, Molnupiravir, lithutong tsa laboratori, e bonts'itse ts'ebetso khahlano le ntaramane ea selemo le ea linonyana, vaerase ea syncytial ea ho hema, vaerase ea chikungunya, vaerase ea Ebola, vaerase ea Venezuela ea equine encephalitis, le vaerase ea Eastern equine encephalitis.Molnupiravir qalong e etselitsoe ho phekola ntaramane Univesithing ea Emory ke k'hamphani ea ntlafatso ea lithethefatsi ea univesithi, Drug Innovation Ventures at Emory (DRIVE), empa ho tlalehoa e lahliloe kherehloa ka lebaka la mathata a phetoho.E ile ea boela ea fumanoa ke khamphani e thehiloeng Miami ea Ridgeback Biotherapeutics, eo hamorao e ileng ea sebelisana le Merck & Co.Molnupiravir e amohetsoe bakeng sa tšebeliso ea bongaka United Kingdom ka Pulungoana 2021.
