N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1 Purity >99.0% (HPLC) Afatinib Dimaleate Intermediate Factory
Ruifu Chemical Supply Intermediates of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H)-e le 'ngoe CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Lebitso la Lik'hemik'hale | N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine |
Litlhaloso tse tšoanang | N-(3-Chloro-4-Fluorophenyl) -7-Fluoro-6-Nitro-4-Quinazolinamine;(3-Chloro-4-Fluorophenyl) (7-Fluoro-6-Nitroquinazolin-4-yl)amine;4-(3-Chloro-4-Fluoroanilino)-7-Fluoro-6-Nitroquinazoline;Afatinib Intermediate A |
Nomoro ea CAS | 162012-67-1 |
Nomoro ea KAtse | RF-PI2026 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C14H7ClF2N4O2 |
Boima ba Molek'hule | 336.68 |
Kutloisiso | Ha e Mamelle Moeeng, Ha e Mamele Mocheso |
Melting Point | 242.0~244.0℃ |
Ntlha e belang | 489℃ |
Botenya | 1.616 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Bosehla bo Khanyang ho isa ho Phofo e Sehla |
Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) |
Tahlehelo ka ho Omisa | <0.50% |
Masalla a ho Ignition | <0.20% |
Lintho Tse Amanang | |
Tšilafalo ea Motho ka Mong | <0.50% |
Litšila ka Kakaretso | <1.00% |
Litšepe tse boima | ≤20ppm |
Infrared Spectrum | E Ikamahanya le Sebopeho |
Proton NMR Spectrum | E Ikamahanya le Sebopeho |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Bohareng ba Afatinib Dimaleate (CAS: 850140-73-7) |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
![1](https://a395.goodao.net/uploads/15.jpg)
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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine (CAS: 162012-67-1) ke karolo e bohareng ea motsoako oa Afatinib Dimaleate (CAS: 850140-73-7) .Afatinib Dimaleate ke mofuta oa letsoai oa Afatinib.Afatinib ke moloko oa bobeli, o tsamaisoang ka molomo, inhibitor e ke keng ea fetoloa ea lelapa la ErbB la tyrosine kinases.Mechanism of ActionAfatinib e theola pontšo ea ErbB ka ho tlama ka mokhoa o ts'oanelang ho lihlopha tsa kinase tsa epidermal growth factor receptor (EGFR), human epidermal growth factor receptor (HER) 2 le HER4, e leng se etsang hore ho be le thibelo e ke keng ea qojoa ea tyrosine kinase autophosphorylation;e boetse e thibela transphosphorylation ea HER3.Afatinib e amoheloa e le monotherapy bakeng sa phekolo ea EGFR tyrosine kinase inhibitor (TKI) - batho ba baholo ba sa tsebeng letho ba nang le sebaka se tsoetseng pele kapa DefinitionChEBI: Letsoai la maleate le fumanoang ka ho kopanya afatinib le likarolo tse peli tsa molar tsa maleic acid.E sebelisoa bakeng sa kalafo ea pele ea bakuli ba nang le mofetše oa matšoafo oa metastatic o seng o monyane.
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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroqui...
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(Dimethylamino)acetaldehyde Diethyl Acetal CAS ...
-
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2...
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Diethylphosphonoacetic Acid CAS 3095-95-2 Purit...
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Trans-4-Dimethylaminocrotonic Acid Hydrochlorid...
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7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449...
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7-Fluoro-6-Nitroquinazolin-4 (1H)-e le 'ngoe CAS 162012...
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Afatinib Dimaleate Mahareng CAS 314771-88-5...
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Afatinib Dimaleate Intermediate CAS 314771-76-1...
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Afatinib CAS 439081-18-2 Bohloeki >99.5% (HPLC) F...
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Afatinib Dimaleate CAS 850140-73-7 Bohloeki >99.5...