N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Tlhahlobo ea 98.5~101.0% Factory High Quality
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) e nang le boleng bo phahameng.Ruifu Chemical e fana ka letoto la li-amino acid le li-derivatives.Ka lebaka la boleng ba sehlahisoa sa rona se setle, litheko tse ntle, re ile ra fumana botumo bo botle hammoho le ts'epo ho tsoa ho bareki ba rona ba lapeng le kantle ho naha.Re ka fana ka COA, phano ea lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Haeba u thahasella N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
Lebitso la Lik'hemik'hale | N-Acetyl-L-Cysteine |
Litlhaloso tse tšoanang | Ac-Cys-OH;Acetylcysteine;NAC;LNAC;N-Acetylcysteine;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine e |
Boemo ba Setoko | Ka Setokong, Bokhoni ba Tlhahiso Lithane tse 50 ka Khoeli |
Nomoro ea CAS | 616-91-1 |
Foromo ea limolek'hule | C5H9NO3S |
Boima ba Molek'hule | 163.19 |
Melting Point | 106.0~108.0℃(lit.) |
E hloahloa | Ha A na Moeeng |
Ho qhibiliha ha Metsi | E qhibilihang ka Metsing, e batla e pepenene |
Solubility | E qhibilihang ka Ethanol, Methanol, Alcohol.Ha e khone ho qhibiliha ka Ether |
Mocheso oa polokelo. | E tiisitsoe ka Dry, Store ka Mocheso oa Kamore |
COA & MSDS | E fumaneha |
Karolelano | Li-Amino Acids le Li-Derivatives |
Brand | Ruifu Chemical |
Lipolelo tsa Kotsi | 36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo. |
Lipolelo tsa Tšireletseho | S22 - U se ke ua hema lerole.S24/25 - Qoba ho kopana le letlalo le mahlo. |
WGK Jeremane | 3 |
RTECS | HA1660000 |
F | 10-23 |
TSCA | Ee |
Khoutu ea HS | 2922491990 |
Lintho | Maemo a Tlhahlobo | Liphetho |
Ponahalo | Likristale tse tšoeu kapa phofo ea Crystalline;Tatso ea Asiti e Matla | E lumellana |
Boitsebiso | Infrared Absorption Spectrum | E lumellana |
Potoloho e Khethehileng [α]20/D | +21.3° ho ea +27.0° (C=5 ho Phosphate Buffered Saline) | +23,5 ° |
Boemo ba Tharollo (Transmittance) | E hlakile ebile ha e na 'Mala ≥98.0% | 99.0% |
Chloride (Cl) | ≤0.040% | <0.040% |
Sulfate (SO4) | ≤0.030% | <0.030% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Tshipi (Fe) | ≤20ppm | <20ppm |
Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
Zinc (Zn) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Lintho Tse Amanang | (Mokhoa oa HPLC) | |
L-cystine | ≤0.50% | E lumellana |
L-cysteine | ≤0.50% | E lumellana |
N,N'-Diacetyl-L-Cystine | ≤0.50% | E lumellana |
N,S-Diacetyl-L-Cysteineine | ≤0.50% | E lumellana |
Emong le emong Ho se hloeke | ≤0.50% | E lumellana |
Litšila ka Kakaretso | ≤0.50% | E lumellana |
Tahlehelo ka ho Omisa | ≤0.50% | 0.20% |
Residue on Ignition (Sulfated) | ≤0.20% | 0.05% |
Tlhahlobo | 98.5 ho isa ho 101.0% (ka Motheo o Omisitsoeng) | 99.90% |
pH Boleng | 2.0 ho isa ho 2.8 (1.0g ho 100ml ea H2O) | 2.5 |
Chefo ea Biochemical | Ho feta | Ho feta |
Lintho tse Fetohang tsa Organic | Feta | Feta |
Ho fumanoa ha Endonuclease | ≤0.1 EU/g | <0.1 EU/g |
Qetello | Sehlahisoa sena ka Tlhahlobo se lumellana le Maemo a AJI97 | |
Lisebelisoa tse ka Sehloohong | Li-amino Acids;Lisebelisoa tsa Lijo;Mekhatlo ea Meriana |
Sephutheloana: Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o pholileng hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) AJI97 Mokhoa oa Teko
N-Acetyl-L-Cysteine, ha e omisitsoe, e na le karolo e ka tlaase ho 98.5 lekholong le e seng ho feta 101.0 lekholong ea N-Acetyl-L-Cysteine (C5H9NO3S).
Tlhaloso: Likristale tse tšoeu kapa phofo ea crystalline, tatso ea acid e matla.
E qhibiliha ka bolokolohi metsing, e qhibiliha ka har'a ethanol, hoo e batlang e sa qhibilihe ka har'a ether.
Sollubility (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Identification: Bapisa spectrum ea infrared absorption ea sampole le ea standard by potassium bromide disc method.
Specific Rotation [α]20/D: Sampole e omisitsoeng, C=8, tharollo ea phosphate buffer
Boemo ba Tharollo (Transmittance): 0.5g ho 10ml ea H2O, spectrophotometer, 430nm, 10mm lisele tse botenya.
Metals e boima (Pb): 2.0g, (1), ref: 2.0ml ea Pb Std.(0.01mg/ml)
Zinc (Zn): Mokhoa oa ho monya athomo
Lintho Tse Amanang: Mokhoa oa HPLC
Tahlehelo ha o Omisa: Ka vacuum, ho 70 ℃ bakeng sa lihora tse 4
Residue on Ignition (Sulfated): AJI Test 13
Tekanyetso: Sampole e omisitsoeng, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g ho 100ml ea H2O
Tekanyo le boemo ba polokelo bo khothalelitsoeng: Lijana tse bolokiloeng tse thata ka mochesong o laoloang oa kamore (lilemo tse 1).
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) USP35 Mokhoa oa Teko
TLHALOSO
Acetylcysteine e na le NLT 98.0% le NMT 102.0% ea L-threonine (C5H9NO3S), e baloang ka mokhoa o omisitsoeng.
TS'ELISO TS'OANE
A. HO AMOHELA INFORARED <197K>
TLHOKOMELO
MOKHOAOA
Mokhahlelo oa selefouno: 6.8 g/L ea monobasic potassium phosphate.Fetola ka asiti ya phosphoric ho pH ya 3.0.
Tharollo ea sodium metabisulfite: 0.5 mg/mL ea sodium metabisulfite ka metsing, e sa tsoa lokisoa
Tharollo e tloaelehileng ea ka hare: 5 mg/mL ea USP L-Phenylalanine RS ka tharollo ea Sodium metabisulfite
Tharollo e tloaelehileng ea setoko: 10 mg/mL ea USP Acetylcysteine RS ka tharollo ea sodium metabisulfite
Tharollo e tloaelehileng: 0.5 mg/mL ea USP Acetylcysteine RS le 0.25 mg/mL ea USP L-Phenylalanine RS ka Sodium metabisulfite solution ho tsoa ho Standard stock solution le Internal standard solution
Mohlala oa tharollo ea setoko: 10 mg/mL ea Acetylcysteine ka tharollo ea sodium metabisulfite
Tharollo ea mohlala: 0.5 mg/mL ea Acetylcysteine le 0.25mg/mL ea USP L-Phenylalanine RS ka tharollo ea Sodium metabisulfite ho tsoa ho Sample stock solution le Internal standard solution
Sistimi ea chromatographic
(Sheba Chromatography <621>, Ho Hlokahala Sistimi.)
Mokhoa: LC
Sesebelisoa: UV 214 nm
Kholomo: 3.9-mm × 30-cm;ho paka L1
Sekhahla sa phallo: 1.5 mL / min
Boholo ba ente: 5 µL
Ho nepahala ha sistimi
[HLOKOMELA-Linako tse lekanyelitsoeng tsa ho boloka acetylcysteine le L-phenylalanine li ka ba 0.5 le 1.0, ka ho latellana.]
Litlhoko tsa ho tšoaneleha
Qeto: NLT 6 pakeng tsa acetylcysteine le L-phenylalanine
Tekanyetso e amanang le maemo: NMT 2.0%
Tlhahlobo
Mehlala: Tharollo e tloaelehileng le Tharollo ea Mohlala
Bala liperesente tsa acetylcysteine (C5H9NO3S) karolong ea Acetylcysteine e nkiloeng:
Sephetho = (RU/RS) × (CS/CU) × 100
RU = karo-karolelano ea tlhōrō ea acetylcysteine ho L-phenylalanine ho tsoa ho Sample solution
RS = karo-karolelano ea tlhōrō ea karabelo ea acetylcysteine ho L-phenylalanine ho tsoa ho tharollo e tloaelehileng
CS = mahloriso a USP Acetylcysteine RS ka har'a tharollo e tloaelehileng (mg/mL)
CU = mahloriso a acetylcysteine ka tharollo ea Sample (mg/mL)
Mekhoa ea ho amohela: 98.0% -102.0% motheong o omisitsoeng
LITŠILA
MASALELA HO THUSA <281>: NMT 0.5%
LITŠEPE TSE BOHLOKO, Mokhoa oa II <231>
[TEMOHELO-Ikoetlise hobane ho ka qhoma.]
Tlhahlobo: Ka mokhoa o fokolang, kolobisa sampole ka 2 mL ea asiti ea nitric, 'me u tsoele pele ka mokhoa o laetsoeng bakeng sa tokiso ea Teko.
Maemo a kamohelo: NMT 10 ppm
LITEKO TSEKO
PHETOHO EA MAIKUTLO, Phapanyetsano e Khethehileng <781S>
Buffer: Kopanya 29.5 mL ea 1 N sodium hydroxide, 50 mL ea 1 M monobasic potassium phosphate, le metsi a lekaneng ho etsa 100 mL.Fetola pH ea 7.0 ± 0.1 ka ho eketsa tharollo efe kapa efe, ha ho hlokahala.
Mohlala oa tharollo: Ka botlolong ea 25-mL ea volumetric, kopanya 1.25 g le 1 mL ea edetate disodium solution (1 ho 100), eketsa 7.5mL ea sodium hydroxide solution (1 ho 25), 'me u kopanye ho qhibiliha.Fokotsa ka Buffer ho ea holimo.
Mekhoa ea ho amohela: +21 ° ho ea ho +27 °
pH <791>: 2.0-2.8 ka tharollo (1 ho 100)
TAHLEHELO KA HO OMETSA <731>: Omisa sampole ka kgatello e ka bang 50 mm ya mer cury ho 70° bakeng sa 4 h: e lahleheloa ke NMT 1.0% ya boima ba yona.
KEKELETSO LIHLOKO
PACKAGER LE POLOKO: Boloka ka har'a lijana tse tiileng, 'me u li boloke mochesong o laoloang oa phaposi.
USP REFERENCE LITEKELO <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Mosebetsi le Tšebeliso ea N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) phofo
1. N-Acetyl-L-Cysteine, eo hape e tsejoang e le N-Acetylcysteine kapa Acetylcysteine (NAC), ke lithethefatsi tsa meriana le phepo e nepahetseng e sebelisoang haholo-holo e le moemeli oa mucolytic le tsamaisong ea paracetamol (acetaminophen) overdose.Litšebeliso tse ling li kenyelletsa phetiso ea sulfate maemong, joalo ka autism, moo cysteine le li-amino acid tse amanang le sebabole li ka fokotsoang.
2. N-Acetyl-L-Cysteine ke motsoako oa cysteine moo sehlopha sa acetyl se khomaretsoeng ho athomo ea nitrogen.Motsoako ona o rekisoa e le tlatsetso ea lijo tse atisang ho bolela hore li-antioxidant le liphello tse sireletsang sebete.E sebelisoa e le moriana oa ho khohlela hobane e khaola maqhama a disulfide ka har'a mamina, 'me e etsa hore ho be bonolo ho khohlela.Hape ke ketso ena ea ho khaola maqhama a disulfide e etsang hore e be molemo ho fokotsa mucus e teteaneng ka mokhoa o sa tloaelehang ho bakuli ba cystic le pulmonary fibrosis.
3. Acetylcysteine ke moemeli oa mucolytic o nang le phello e matla ea mucolytic.Sehlopha sa sulfhydryl se ka har'a molek'hule se ka senya tlamo ea disulfide ka har'a ketane ea glycoprotein polypeptide ka har'a sekhohlela, kahoo sa fokotsa ponahalo ea sekhohlela, 'me sa etsa hore sekhohlela se be bonolo ho khohlela.Sehlahisoa sena se ka boela sa senya likhoele tsa DNA ka sekhohlela sa purulent, kahoo se ke ke sa qhala sekhohlela se tšoeu feela, empa hape le sekhohlela sa purulent.Bakeng sa bakuli bao li-expectorants ka kakaretso li sa sebetseng, sehlahisoa sena se ntse se ka sebetsa.
4. E sebelisoa e le moriana oa ho qhaqha phlegm.E sebelisoa lipatlisisong tsa biochemical le meriana e le pheko bakeng sa chefo ea phlegm le acetaminophen.Biochemical reagent, meriana, sehlahisoa sena se sebelisoa e le expectorant, se boletse hore phlegm e bonolo ho hloekisa.
5. Litla-morao tse tloaelehileng li kenyelletsa ho nyekeloa ke pelo le ho hlatsa ha motho a nooa ka molomo. Letlalo le ka 'na la e-ba khubelu le ho hlohlona ka mofuta ofe kapa ofe.Ho ka 'na ha boela ha e-ba le mofuta o sa sireletsehang oa anaphylaxis.Ho bonahala ho bolokehile nakong ea bokhachane.Bakeng sa overdose ea paracetamol, e sebetsa ka ho eketsa boemo ba glutathione, antioxidant e ka fokotsang lihlahisoa tse chefo tsa paracetamol.Ha e hema, e sebetsa e le mucolytic ka ho fokotsa botenya ba mucus.
6. Acetylcysteine e ile ea qala ho fuoa tokelo ea molao ka 1960 'me ea qala ho sebelisoa bongaka ka 1968. E lethathamong la Mokhatlo oa Lefatše oa Bophelo ba Lethathamo la Meriana ea Bohlokoa, le thathamisang meriana e sireletsehileng le e sebetsang ka ho fetisisa e hlokahalang tsamaisong ea bophelo bo botle.E fumaneha e le meriana e akaretsang 'me e theko e tlaase.
7. N-Acetyl-L-Cysteine ke mofuta oa acetylated oa L-cysteine o kenang ka katleho le ho sebelisoa.Hape ke antioxidant e thusang khahlanong le livaerase.N-Acetyl-l-Cysteine e 'nile ea sebelisoa e le tšireletso ea sebete le ho pshatla mats'oafo le bronchial mucus.
8. N-Acetyl-L-Cysteine e ka matlafatsa maemo a glutathione liseleng.
9. N-Acetyl-L-Cysteine ke amino acid e hlokahalang maemong, e 'ngoe ea li-amino acid tse tharo feela tse nang le sebabole, tse ling e le taurine (e ka hlahisoang ho tsoa ho L-cysteine) le L-methionine eo L-cysteine e ka khonang ho tsoa ho eona. ho hlahiswa mmeleng ka methati e mengata.
10. N-Acetyl-L-Cysteine e ka sebetsa e le antioxidant, e ka thibela maloetse a sebete, 'me e ka thusa ho tiisa bophara ba moriri o teng haeba e nkoa kamehla.
11. Kopo likarolong tsa bongaka Joaloka moemeli oa tsamaiso ea ho phefumoloha, e ka sebelisoa e le moriana oa ho qhaqha meropa ea phlegm.e ka phekola bronchitis.ho feta moo, N-Acetyl-L-Cysteine e ka sebelisoa e le pheko ha chefo ea acetaminophen.
12. Ts'ebeliso libakeng tsa litlolo N-Acetyl-L-Cysteine e na le phello e ntle ea ho hlakola li-radicals tsa mahala tsa oksijene le li-oxide tse ling le ho liehisa ts'ebetso ea botsofali, le eona e ka sitisa tlhahiso ea melanin, 'me e thusa ho felisa letheba letlalong.
13. Ho sebelisoa lijong tsa liphoofolo N-Acetyl-L-Cysteine e ka sebelisoa e le sehlomathiso sa phepo.
14. Litlolo tse sebelisoang haholo bakeng sa metsi a botle, perm fluid, tranelate ea tlhokomelo ea letlalo e sireletsang letsatsi.E na le mosebetsi oa ho thibela botsofali ba likokoana-hloko.N-Acetyl-l-Cysteine e khona ho thibela le ho phekola kotsi ea mahlaseli.N-acetyl Cysteine e ka tlosa melanin ea letlalo ka boeona, ea fetola tlhaho ea letlalo ka boeona, letlalo le fetoha bosoeu ba tlhaho.Ke mofuta o motle oa litlolo tsa tlhaho tsa tlhaho.
15. Tlatsetso ea lijo.E sebelisoa ka bohobe, ho khothalletsa ho thehoa ha gluten le ho khothalletsa ho belisoa, hlobo, ho thibela botsofali.E sebelisoa ka lero la tlhaho ho thibela vithamine C ho tsoa ho oxidizing le ho thibela lero hore le se ke la fetoha sootho.