N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Tlhahlobo ea 99.0~101.0 Fektheri
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) e nang le boleng bo phahameng.Ruifu Chemical e fana ka letoto la li-amino acid le li-derivatives.Sehlahisoa sa boleng bo holimo, theko e tlase, ts'ebeletso e ntle haholo le e potlakileng kamora thekiso ke boitlamo ba Ruifu Chemical ho bareki.Re ka fana ka COA, phano ea lefats'e ka bophara, tse nyane le tse ngata tse fumanehang.Haeba u thahasella N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | N-Acetyl-L-Tyrosine |
| Litlhaloso tse tšoanang | Ac-Tyr-OH;Ac-L-Tyr-OH;N-Ac-L-Tyr;NALT;Ac-Tyrosine;Acetyltyrosine;N-Acetyltyrosine;Acetyl-Laevo-Tyrosine;LN-Acetyltyrosine;(2S) -2-(Acetylamino) -3-(4-Hydroxyphenyl)Propanoate;(S) -2-Acetamido-3-(4-Hydroxyphenyl)propanoic Acid;N-Acetyl-(S)-2-Amino-3-(4-Hydroxyphenyl)propionic Acid;(2S) -2-(Acetylamino)-3-(4-Hydroxyphenyl)propanoic Acid |
| Boemo ba Setoko | Ka Setokong, Bokhoni ba Tlhahiso Lithane tse 30 ka Selemo |
| Nomoro ea CAS | 537-55-3 |
| Foromo ea limolek'hule | C11H13NO4 |
| Boima ba Molek'hule | 223.23 g/mol |
| Melting Point | 150.0 ho isa ho 154.0 ℃ |
| Botenya | 1.304 |
| Ho qhibiliha ha Metsi | E qhibilihang ka Metsing, e batla e pepenene |
| Mocheso oa polokelo. | E tiisitsoe ka Dry, Store ka Mocheso oa Kamore |
| COA & MSDS | E fumaneha |
| Karolelano | Li-Amino Acids le Li-Derivatives |
| Brand | Ruifu Chemical |
| Likhoutu tsa Kotsi | Xi - Ea halefisang | F | 10 |
| Lipolelo tsa Kotsi | 41-36/37/38 | TSCA | Ee |
| Lipolelo tsa Tšireletseho | 26-39-36 | Khoutu ea HS | 2922491990 |
| WGK Jeremane | 3 |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Likristale tse tšoeu kapa phofo ea Crystalline | E lumellana |
| Boitsebiso | Infrared Absorption Spectrum | E lumellana |
| Potoloho e Khethehileng [α]20/D | +46.5° ho ea ho +49.0°(C=2 ho H2O) | +47,2° |
| Boemo ba Tharollo (Transmittance) | ≥96.0% | 98.3% |
| Chloride (Cl) | ≤0.020% | <0.020% |
| Sulfate (SO4) | ≤0.020% | <0.020% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Tshipi (Fe) | ≤30ppm | <30ppm |
| Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤2.0ppm | <2.0ppm |
| Tyrosine | ≤1.00% | E lumellana |
| Tahlehelo ka ho Omisa | ≤0.50% | 0.25% |
| Residue on Ignition (Sulfated) | ≤0.10% | 0.07% |
| Tlhahlobo | 99.0 ho isa ho 101.0% | 99.5% |
| pH Boleng | 2.0 ho isa ho 3.0 | 2.3 |
| Qetello | E kopana le Maemo a AJI97, USP35 | |
| Lisebelisoa tse ka Sehloohong | Lisebelisoa tsa Lijo;Lisebelisoa tsa Lijo;Mekhatlo ea Meriana | |
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) AJI97 Mokhoa oa Teko
N-Acetyl-L-Tyrosine, ha e omisitsoe, e na le karolo e ka tlaase ho 99.0 lekholong le e seng ho feta 101.0 lekholong ea N-Acetyl-L-Tyrosine (C11H13NO4).
Tlhaloso: Likristale tse tšoeu kapa phofo ea crystalline, tatso ea acid e matla
Ho qhibiliha ka bolokolohi metsing.
Sollubility (H2O, g/100g): 17.5 (20℃), 72.4 (40℃), 158 (60℃)
Identification: Bapisa spectrum ea infrared absorption ea sampole le ea standard by potassium bromide disc method.
Potoloho e Khethehileng [α]20/D: Mohlala o omisitsoeng, C=4, H2O
Boemo ba Tharollo (Transmittance): 0.5g ho 10ml ea H2O, spectrophotometer, 430nm, 10mm lisele tse botenya.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml ea 0.01mol/L HCl
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ea 0.005mol/L H2SO4
Tšepe (Fe): 0.5g, ref: 1.5ml ea Iron Std.(0.01mg/ml)
Litšepe tse boima (Pb): 2.0g, (3), ref: 2.0ml ea Pb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), ref: 2.0ml ea As2O3 Std.
Tahlehelo ha o Omisa: ho 105 ℃ bakeng sa lihora tse 3
Residue on Ignition (Sulfated): AJI Test 13
Assay: Sampole e omisitsoeng, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: Mokelikeli oa chromatography.Boemo ba ho sebetsa: Mofuputsi: Photometer ea ho monya UV (214nm);Kholomo: ODS, 4.6mm x 150mm;Mocheso oa Kholomo: Mocheso oa kamore.Sekhahla sa phallo: 1ml / min;Mokhahlelo oa selefouno: 0.04mol/L tharollo ea monopotassium phosphate (pH 4.35): Methanol (193:3)
pH: 1.25g ho 50ml ea H2O
Moeli le boemo bo khothalelitsoeng ba polokelo: Lits'oants'o tse tiileng tse bolokiloeng mochesong o laoloang oa phaposi (lilemo tse 2).
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) USP35 Mokhoa oa Teko
TLHALOSO
N-Acetyltyrosine e na le NLT 98.5% le NMT 101.0% ea C11H13NO4, joalo ka N-Acetyl-L-Tyrosine, e baloang ho latela omisitsoeng.
TS'ELISO TS'OANE
A. HO AMOHELA INFORARED <197K>
B. HO PHETOHA HO BONAHALA, HO FETOLA HO TŠOANYEHA <781S>
Tharollo ea mohlala: 10 mg/mL
Mokhoa oa ho amohela: NLT +46.0° le NMT +49.0°, e khethiloeng ho 20°
C. Theko ea RF ea sebaka se ka sehloohong sa tharollo ea Mohlala tekong ea Organic Impurities e lumellana le ea tharollo e Tloaelehileng ea 1.
TLHOKOMELO
MOKHOAOA
Tharollo ea mohlala: Qhala hoo e ka bang 180 mg ea N-Acetyltyrosine, e lekantsoeng, ka 50 ml ea metsi a se nang carbon dioxide.
Sistimi ea Titrimetric
(Sheba Titrimetry <541>)
Mokhoa: Titration e tobileng
Titrant: 0.1 N sodium hydroxide VS
Ho lemoha lintlha tsa ho qetela: Potentiometric
Tekano: ML ka 'ngoe ea 0.1 N sodium hydroxide VS e lekana le 22.32 mg ea C11H13NO4.
LITŠILA
Tšilafalo ea Inorganic
HO HLAHALA HO HLAHALA <281>: NMT 0.1%
CHLORIDE LE SULFATE, Chloride <221> NMT 200 ppm.Karolo ea 0.7-g ha e bontše chloride e fetang 0.40 mL ea 0.01 N hydrochloric acid.
CHLORIDE LE SULFATE, Sulfate <221> NMT 200 ppm.Karolo ea 1.2-g ha e bontše sulfate ho feta 0.25 mL ea 0.020 N sulfuric acid.
IRON <241>: NMT 20ppm
LINTLHA TSE BOHLOKO, Mokhoa oa I <231>: NMT 10ppm
Litšila tsa Organic
MOKHOAOA
Adsorbent: 0.25-mm lera la chromatographic silica gel motsoako
Tharollo e tloaelehileng ea setoko 1: 8 mg/mL ea USP N-Acetyl-L-tyrosine RS ka motsoako oa metsi, glacial acetic acid, le joala (3:3:94)
Tharollo e tloaelehileng ea 1: Hlakola tharollo e tloaelehileng ea setoko sa 1 ka joala ho fumana tharollo e nang le motsoako o ka bang 0.4 mg/mL.
Tharollo e tloaelehileng ea 2: 0.8 mg/mL ea USP L-Tyrosine RS e qhibilihisoa ka motsoako oa glacial acetic acid le metsi (1:1), 'me e hlapolotsoe ka joala.
Mohlala oa tharollo: Fetisetsa 0.8 g ea N-Acetyltyrosine ho 10-mL volumetric flask, qhala ka 6 ml ea motsoako oa glacial acetic acid le metsi (1: 1), 'me u hlapolle ka joala ho ea holimo.
Bophahamo ba kopo: 5 µL
Ho ntshetsa pele tsamaiso ya solvent: Motswako wa ammonia le 2-propanol (3:7)
Sehlahisoa sa spray: Qhala 0.2 g ya ninhydrin ka 100 ml ea motsoako oa butanol le 2 N acetic acid (95:5).
Ho nepahala ha sistimi
Litlhoko tsa ho tšoaneleha: Chromatogram ea tharollo ea ts'ebetso ea Sistimi e bonts'a matheba a mabeli a arohaneng ka ho hlaka.
Tlhahlobo: Tsoela pele joalo ka ha ho laetsoe Chromatography <621> Thin-Layer Chromatography.Kamora ho omisa poleiti ka moea, pheta ts'ebetso ea nts'etsopele.Kamora ho omisa moeeng kgetlo la bobedi, fafatsa ka sehlahiswa sa Spray, mme o futhumale pakeng tsa 100° le 105° ka metsotso e ka bang 15.
Mokhoa oa ho amohela: Sebaka sefe kapa sefe sa bobeli sa tharollo ea Sample ha se seholo kapa se tebile ho feta sebaka sa mantlha sa Tharollo e Tloaelehileng1, ntle le sebaka se tsamaellanang le tyrosine, se seng se seholo kapa se matla ho feta sebaka sa mantlha ho tsoa ho Standard solution 2.
Litšila tsa motho ka mong: NMT 0.5%
Moeli oa tyrosine: NMT 1.0%
LITEKO TSEKO
HO OMETSA LOSSON <731>: Omisa sampole ho 105℃ bakeng sa 3 h: e lahleheloa ke NMT 0.1% ea boima ba eona.
KEKELETSO LIHLOKO
PAKARETSO LE HO BOLOKA: Boloka ka har’a linkho tse koetsoeng hantle, ’me u li boloke mochesong o laolehileng oa kamore.
USP REFERENCE LITEKELO <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS
Sephutheloana: Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o pholileng hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.Qoba hole le mahlahana a matla a oxidizing.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Mosebetsi le Tšebeliso ea N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) phofo
1. N-Acetyl-L-Tyrosine ke motsoako oa acetyl oa amino acid, L-tyrosine.E qhibiliha ka bolokolohi metsing ha e bapisoa le L-tyrosine 'me hangata e sebelisoa e le tlatsetso ea phepo ea batsoali.N-Acetyl-L-Tyrosine, mofuta o tsitsitseng le o tsitsitseng haholoanyane oa tyrosine, o kenyelelitsoe ho tse ling tse teng hona joale tsa khoebo ea parenteral amino acid formulations tse kang TrophAmine le Aminosyn-II.
2. N-Acetyl-L-Tyrosine e ameha tlhahisong ea catecholamine.E ka sebelisoa e le karolo ea mecha ea litaba ea setso sa lisele ho biomanufacture ea khoebo ea liprotheine tse nchafatsang tsa kalafo le li-antibodies tsa monoclonal.
3. N-Acetyl-L-Tyrosine ke amino acid ea bohlokoa, e leng mofuta oa phepo ea bohlokoa bakeng sa metabolism ea batho le liphoofolo, kholo le nts'etsopele li phetha karolo ea bohlokoa, li ka sebelisoa haholo lijong, meriana joalo-joalo.
4. N-Acetyl-L-Tyrosine e phetha karolo e hlokahalang ho kopanngoa ha dopamine le lihomone tse ling 'meleng oa hau.E ka eketsa maemo a li-neurotransmitters dopamine, norepinephrine le epinephrine.E thusa ho ts'ehetsa maemo a holimo a ho tsepamisa maikutlo le ts'ebetso ea kelello.E ka eketsa mohopolo o sebetsang le maikutlo a boiketlo.
5. N-Acetyl-L-Tyrosine e fetotsoe ho tloha ho Tyrosine e tloaelehileng hobane e na le tlatsetso ea acetic acid.Sena se hlile se thusa ho eketsa bioavailability ea motsoako e le hore e kene hantle ka ho toba maling.
6. N-Acetyl-L-Tyrosine ke mofuta o phahameng oa bioavailable oa L-Tyrosine bakeng sa phekolo ea pele ea tlhaho ea maikutlo a tlaase N-Acetyl-L-Tyrosine e ka sebelisoa ka tekanyo e tlaase ho feta L-Tyrosine.L-Tyrosine e tloaelehileng ha e tsitsitse ebile ha e qhibilihe metsing, e leng se ka bakang ho fokotseha ha bioavailability.
7. N-Acetyl-L-Tyrosine e ntlafatsa ho qhibiliha le ho tsitsa ho etsa hore e be mokhoa o potlakileng le o fumanehang oa bioavailable oa amino acid L-Tyrosine e sa tloaelehang haholo ho tsoa moroto.
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