N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Coupling Reagent Purity >99.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: N-Hydroxysuccinimide

Mantsoe a tšoanang: HOSu;NHS

CAS: 6066-82-6

Bohloeki: >99.0% (HPLC)

Ponahalo: Phofo e tšoeu ea Crystalline

Coupling Reagent bakeng sa Peptide, Boleng bo Phahameng

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6) e nang le boleng bo phahameng.Ruifu Chemical e fana ka letoto la li-reagents tse sireletsang le li-reagents tse kopanyang.Ruifu e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, palo e nyane le e ngata e fumanehang.Reka N-Hydroxysuccinimide,Please contact: alvin@ruifuchem.com

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale N-Hydroxysuccinimide
Litlhaloso tse tšoanang HOSu;NHS;1-Hydroxysuccinimide;1-Hydroxy-2,5-Pyrrolidinedione;N-Hydroxy-2,5-dioxopyrrolidine
Boemo ba Setoko In Stock, Mass Production
Nomoro ea CAS 6066-82-6
Foromo ea limolek'hule C4H5NO3
Boima ba Molek'hule 115.09 g/mol
Melting Point 93.0~98.0℃(lit.)
Botenya 1.649
E hloahloa Hygroscopic.Mocheso o Mamela, Ha o Mongobo
Solubility ka Dioxane E qhibiliha ka Dioxane, Hoo e ka bang Transparency
Sollubility ka Metsing E qhibilihang ka Metsing
Mocheso oa polokelo. Sebaka se pholileng le se omileng (2~8℃)
COA & MSDS E fumaneha
Sehlopha Coupling Reagents
Brand Ruifu Chemical

Litlhaloso:

Lintho Maemo a Tlhahlobo Liphetho
Ponahalo Phofo e Tšoeu ea Crystalline E lumellana
Melting Point 93.0~98.0℃ 94.0~97.0℃
Tahlehelo ka ho Omisa <0.50% 0.15%
Mokhoa oa Bohloeki / Analysis >99.0% (HPLC) 99.5%
Infrared Spectrum E Ikamahanya le Sebopeho E lumellana
Proton NMR Spectrum E Ikamahanya le Sebopeho E lumellana
Qetello Sehlahisoa se lekoa 'me se lumellana le litlhaloso

Mokhoa oa Teko:

Mokhahlelo oa selefouno: 0.1% tharollo ea phosphoric acid: acetonitrile =90:10
Wavelength: 220nm
Sekhahla sa phallo: 1ml/min

Sephutheloana/Bobolokelo/Ho tsamaisa ka sekepe:

Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Ha e na le mongobo.Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng le se omileng (2~8℃) hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Fana ka lefatše ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

Bokhoni bo lekaneng: Lisebelisoa le litsebi tse lekaneng

Tšebeletso ea profeshenale: Tšebeletso e le 'ngoe ea ho reka

Sephutheloana sa OEM: Sephutheloana sa tloaelo le leibole lia fumaneha

Tlhahiso e potlakileng: Haeba e le ka har'a setoko, ho netefalitsoe hore ho tsamaisoa matsatsi a mararo

Thepa e tsitsitseng: Boloka thepa e lekaneng

Tšehetso ea Theknoloji: Tharollo ea theknoloji e teng

Tšebeletso e Tloaelehileng ea ho Kopanya: Ho tloha ho ligrama ho isa ho lik'hilograma

Boleng bo Phahameng: Ho thehile tsamaiso e felletseng ea netefatso ea boleng

LBH:

Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.

Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.

Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.

BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.

Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.

Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.

MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.

Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.

Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.

Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.

Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.

Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.

6066-82-6 - Kotsi le Tšireletseho:

Matshwao a Kotsi Xi - E tenang
Likhoutu tsa Kotsi
36/37/38 - Ho halefisa mahlo, tsamaiso ea ho hema le letlalo.
Tlhaloso ea Tšireletseho
S22 - U se ke ua hema lerole.
S24/25 - Qoba ho kopana le letlalo le mahlo.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36 - Apara liaparo tse loketseng tsa tšireletso.
WGK Jeremane 3
TSCA Ho joalo
HS Code 2925190090
Hazard Note Irritant

Kopo:

N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent bakeng sa ho lokisetsa li-ester tse sebetsang tsa amino acid.Peptide solid phase synthesis e hokahanyang moemeli.
N-Hydroxysuccinimide e atisa ho sebelisoa ho thusa ho kopanya peptide ea carbodiimide-mediated ka ho etsa ester e sebetsang e bohareng ka condensation ea top carboxyl sehlopha le NHS.NHS-reactive ester intermediate e ka hlaseloa ke nucleophilic ka li-amine tsa mantlha 'me e fella ka ho thehoa ha li-amide tse tsitsitseng pakeng tsa sebaka sa biomaterial le N-terminus ea peptide.
N-Hydroxysuccinimide ke hydroxylated succinimide e sebelisoang haholo ho kenya ts'ebetsong ea li-carboxylic acid ho NHS-esters ho khothalletsa ho kopana le nucleophiles.Mokhoa ona o sebelisoa haholo ho kenya tšebetsong mefuta ea asiti ea mahala ea fluorophores bakeng sa ho khothaletsa khokahanyo ea li-fluorophore tsena ho masala a amine a liprotheine.Tšebeliso ea NHS ester activation e boetse e hlalositsoe ka ho qaptjoa ha N-acyl amino acid.
E sebelisoa bakeng sa ho qaptjoa ha amino acid e sireletsang, semi-synthetic kanamycin le li-intermediates tsa meriana.N-hydroxybutyldiimide le lihlahisoa tsa eona ke lisebelisoa tsa bohlokoa bakeng sa motsoako oa li-peptide, lithibela-mafu, li-amino acid le liprotheine.N-hydroxybutyldiimide e sebelisoa ha ho etsoa litokisetso tse sebetsang esters, le thibelo ea phello ea optically e sebetsang ea ho kopanya peptide e na le mefuta e mengata ea li-USES meriana, hape ke lisebelisoa tsa motheo tsa lik'hemik'hale.
N-Hydroxysuccinimide e sebelisetsoa ho ntlafatsa li-amidations ka mokhoa oa carbodiimide.E boetse e sebelisoa ho kenya tšebetsong sehlopha sa carboxyl mme e kopana le amine ho theha amide.E ameha ho lokiseng N-hydroxymaleimide-styrene copolymer.

Mokhoa oa Tlhahiso:

N-Hydroxysuccinimide e ile ea lokisoa ka tsela e latelang: 100g (1.0mol) succinic anhydride le 70g (1.0mol) ea hydroxylamine hydrochloride e futhumatsoa hammoho, tsamaiso ea karabelo e bolokoa tlas'a khatello e mpe ea ho tlosa li-volatile tse hlahisitsoeng, 'me e futhumatsoa ka potlako ho feta 125 ℃. , ebe butle-butle e nyolohela ho 160 ℃ ka mor'a 1H.Ho futhumatsa ho ile ha emisoa mme ha mocheso o theohela ho 125 ℃, karabelo ea mokelikeli e ile ea tšeloa ka har'a diethyl ether 'me ea tsosoa ka matla.Ka mor'a hore sehlahisoa se phekoloe, lesela la ether le ile la tlosoa, sehlahisoa se phekotsoeng se futhumatsoa ho bela ka 400ml ea butanol, e chesang e tlhotliloeng, 'me filtrate e ile ea pholile ka potlako ho 0 ℃.Ka mor'a ho hloekisoa ha 1H, likristale li ile tsa hlatsuoa ka ho latellana ka butanol le diethyl ether, 'me sehlahisoa se se nang mafura se fumanoeng se ile sa tsosolosoa ho tloha ethyl acetate ho fumana 50g ea sehlahisoa se felileng ka 44% ea lihlahisoa.

Ngola molaetsa wa hao mona mme o re romele wona