Octreotide Acetate CAS 83150-76-9 Peptide Purity (HPLC) ≥98.0% API Boleng bo Phahameng

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Octreotide Acetate

CAS: 83150-76-9

Ponahalo: Phofo e tšoeu

Peptide Purity (Ka HPLC): ≥98.0%

Tlhaloso: 95% ~ 105%

Lihlahala tsa Acromegaly le Gastroenteropancreatic

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Octreotide Acetate (CAS: 83150-76-9) e nang le boleng bo phahameng.Ruifu Chemical e fana ka letoto la li-peptide tsa GMP.Ruifu e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, palo e nyane le e ngata e fumanehang.Reka Octreotide Acetate,Please contact: alvin@ruifuchem.com

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale Octreotide Acetate
Litlhaloso tse tšoanang SMS 201-995;Samilstin;Octreotide-LAR;
Tatelano D-Phe-c[Cys-Phe-D-Trp-Lys-Thr-Cys]-Thr-ol
TSOSOA [FCFWKTCT(Disulfide Bridge: Cys2-Cys7)]
Nomoro ea CAS 83150-76-9
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lik'hilograma
Foromo ea limolek'hule Setšoantšo sa C49H66N10O10S2
Boima ba Molek'hule 1019.24
Melting Point >140℃(Dec.)
Botenya 1.39±0.10 g/cm3
Solubility E qhibiliha ka Acetic Acid, DMSO, le Methanol
Botsitso Hygroscopic
Mocheso oa polokelo. Sebaka se pholileng le se omileng (2~8℃).Sehatsetsi
Tokomane COA, MS, HPLC, NMR, MSDS, joalo-joalo.
Sehlopha Li-peptide tsa GMP
WGK Jeremane 3
Litlhoko tsa ho Romela Mekotla ea leqhoa, Mekotla ea Desiccant
Brand Ruifu Chemical

Litlhaloso:

Lintho Maemo a Tlhahlobo Liphetho
Ponahalo Phofo e Tshweu Phofo e Tshweu
Solubility Soluble ka Metsing kapa 1% Acetic Acid ho Concentration of ≥1mg/ml ho Fana ka Tharollo e Hlakileng e se Na Mebala. E lumellana
Amino Acid Analysis (Ka HPLC) Nako: 0.7 ~ 1.1 0.9
Cys: 1.0 ~ 2.2 1.9
Lits'oants'o: 0.9 ~ 1.3 1.1
Phe: 1.8~2.2 1.9
Thr-OL: 0.6 ~ 1.3 0.9
Leeto: 0.4 ~ 1.1 0.8
Peptide Purity (Ka HPLC) ≥98.0% (ka Area Integration) 99.81%
Lintho tse Amanang (Ka HPLC) Kakaretso ea Litšila (%) ≤2.0% 0.19%
Tšilafalo e Kholo e le 'Ngoe (%) ≤1.0% 0.12%
Litaba tsa Acetate (HPLC) 5.0~12.8% 9.6%
Litaba tsa Metsi (Karl Fischer) ≤7.0% 2.7%
Litaba tsa TFA (Karl Fischer) ≤0.25% 0.13%
Specific Optical Rotation -45.0°~-55.0° (C=0.5, 95% HAc) -51.5°
Tlhahlobo 95.0 ~ 105.0% (E senang metsi, Acetic Acid Free) 99.0%
Tšimoloho ea Sehlahisoa Synthetic  
Tlhokomeliso Feela Bakeng sa Lipatlisiso, Eseng Bakeng sa Tšebeliso ea Batho  
Qetello Sehlahisoa se lekoa 'me se lumellana le litlhaloso
Tšebeliso Li-peptide tsa GMP;Active Pharmaceutical ingredient (API)

Sephutheloana le Bobolokelo:

Sephutheloana:Vial ea polasetiki (e nehetsoeng ho paka peptide) kapa vial ea khalase, bongata ho latela tlhoko ea lintlha tsa moreki.
Boemo ba polokelo:Boloka ka lijaneng tse tiisitsoeng sebakeng sa polokelo se pholileng le se omileng (2~8℃) hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Fana ka lefatše ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

1

LBH:

www.ruifuchem.com

Kopo:

Octreotide Acetate (Sandostatin) ke analogue ea maiketsetso ea peptide ea hormone somatostatin, ke analoge ea nako e telele ea somatostatin e bonts'itsoeng taolo ea matšoao ho lihlahala tsa acromegaly le gastroenteropancreatic.Litšebeliso tse ling tse ntseng li etsoa lipatlisisong li kenyelletsa lefu la tsoekere, psoriasis le lefu la Alzheimer's.Octreotide Acetate (Sandostatin) ke analogue ea maiketsetso ea peptide ea hormone somatostatin.Liketso tsa eona li kenyelletsa ho thibela secretion ea pituitary ea kholo ea hormone le ho thibela tlhahiso ea lisele tsa "pancreatic islet cell" tsa insulin le glucagon.Ho fapana le somatostatin, e nang le halofo ea bophelo ba plasma ea metsotso e seng mekae, Octreotide e na le halofo ea bophelo ea plasma ea lihora tse 1 ho isa ho tse peli.Excretion ea lithethefatsi ke haholo-holo renal.Octreotide e fokotsa ho tsamaea ha gastrointestinal le ho thibela ho honyela ha nyooko.

Lithethefatsi tsa Peptide Novartis Sandostatin (Octreotide Acetate), ke motsoako oa tlhaho oa tlhaho oa somatostatin octapeptide, o boloka phello ea pharmacological e tšoanang le ea somatostatin, 'me phello e tšoarella nako e telele.Lipontšo tsa Octreotide Acetate li kenyelletsa acromegaly;Phokotso ea matšoao le matšoao a amanang le tšebetso ea gastroenteropancreatic endocrine neoplasia;Le katleho ho Lihlahala tsa Carcinoid tse hlahisang lefu la carcinoid, VIP tumors, le glucagon tumors.Ntle le moo, Octreotide Acetate bakeng sa lefu la gastrinomas/Zollinger-Ellison (hangata e kopantsoe le proton pump inhibitors kapa H2 receptor blockers), Insulinomas (thibelo ea pele ho ts'ebetso ea hypoglycemia le tlhokomelo ea tsoekere e tloaelehileng ea mali), sekhahla se sebetsang sa kholo ea li-hormone tse lokollang sesosa sa hlahala ke. hoo e ka bang 50%.

Octreotide Acetate ke sethethefatsi sa naha sa inshorense ea bophelo bo botle sa Sehlopha sa B, e leng motsoako oa tlhaho oa octapeptide o tsoang ho somatostatin, ha o bapisoa le somatostatin ea tlhaho, ho hlakile hore halofo ea bophelo ea somatostatin e lelefalitsoe mme e na le litlamorao tse tšoanang tsa pharmacological, ho kenyelletsa le ho thibela tšebetso ea lihormone tsa kholo, thibelo. ka gastric acid, pancreatic enzyme, glucagon le secretion ea insulin, le phokotso ea phallo ea mali ea visceral, e fokotsehile motility ea mala.Ha e bapisoa le somatostatin ea tlhaho, octreotide e na le halofo ea nako e telele ea bophelo, e khetha ho thibela secretion ea kholo ho feta ho thibela tlhahiso ea insulin, 'me ha e bake hypersecretion e eketsehileng ea hormone.1, Ho laola ho buuoa kapa phekolo ea mahlaseli a kotsi ha e khone ho laola lefu lena ka ho lekaneng ho bakuli ba nang le matšoao a acromegaly le ho fokotsa boemo ba mokuli ba hormone ea kholo (GH) insulin-like growth factor -1 (1GF-1) plasma.Sandostatin e ka boela ea sebelisoa ho phekola bakuli ba nang le acromegaly ba sa khoneng kapa ba sa ikemisetsang ho buuoa, kapa ho phekola bakuli ba nang le acromegaly ba e-s'o fumane phekolo ea mahlaseli.2. Ho fokotsa matšoao a amanang le lihlahala tse sebetsang tsa gastroenteropancreatic (GEP) tse kang lihlahala tsa carcinoid tse nang le lipontšo tsa lefu la carcinoid.Sandostatin ha se setlhare se thibelang mofetše ebile ha se phekole bakuli bana.3, Thibelo ea mathata ka mor'a ho buuoa ka pancreatic.4, bakuli ba nang le lefu la sebete sa sebete sa "gastric-esophageal variceal" le bakoang ke kalafo ea tšohanyetso, hemostasis le thibelo ea ho tsoa mali hape, Sandostatin e lokela ho kopanngoa le endoscopic sclerotherapy le kalafo e 'ngoe e khethehileng.

83150-76-9 - Tšireletseho:

Litla-morao tsa sehlahisoa sena ke Mahlaba a Mpa, ho ferekana ka mpeng, Letšollo, steatorrhea;sebopeho sa Gallstone;Mamello ea glucose e ka fokotseha kapa ea mpefala nakong ea pele ea kalafo, ebe joale e ka ntlafatsoa;Tšebeliso ea nako e telele ntle le tlhahiso ea endogenous antibody, ho ne ho se na karabelo e hlakileng kapa e mpe ha moriana o emisoa kapa o fokotseha ka potlako.2 ~ 8 deg C bakeng sa polokelo ea nako e telele.

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