Olopatadine Hydrochloride Intermediate CAS 27710-82-3 Bohloeki >99.0% (HPLC)
Mofani ea ka sehloohong oa Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | [3-(Dimethylamino) propyl]triphenylphosphonium Bromide Hydrobromide |
| Litlhaloso tse tšoanang | (3-Dimethylaminopropyl)triphenylphosphonium Bromide HBr |
| Nomoro ea CAS | 27710-82-3 |
| Nomoro ea KAtse | RF2698 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C23H28Br2NP |
| Boima ba Molek'hule | 509.27 |
| Melting Point | 283.0~285.0℃ |
| Botsitso | Hygroscopic |
| Solubility | Chloroform (Hanyenyane), Methanol (Hanyenyane) |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Bosoeu ho isa ho bosoeu ba Crystal Powder |
| Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) |
| Mokhoa oa ho hlahloba / oa ho hlahloba | >99.0% (Titration) |
| Tahlehelo ka ho Omisa | <0.50% |
| Tšilafalo e le Mong | <0.50% |
| Litšila ka Kakaretso | <1.00% |
| 1 H NMR Spectrum | E Lumellanang le Sebopeho |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Bohareng ba Olopatadine Hydrochloride (CAS: 140462-76-6) |
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[3-(Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) ke bohareng ba Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride ke sethethefatsi se khahlanong le allergic.E na le liphello tse peli tsa ho thibela ho lokolloa ha histamine le ho khetha ho hanyetsa li-receptor tsa HI, 'me ha e na thibelo ea tsamaiso ea methapo e bohareng le litla-morao tse chefo tsa pelo tse tloaelehileng ka lithethefatsi tsa antiallergic tsa HI receptor.Olopatadine Hydrochloride e ke ke ea thibela feela ho lokolloa ha histamine liseleng tsa mast, empa hape e hanyetsa li-receptor tsa H1 ka mokhoa o ikhethileng, 'me ha e na phello ho li-receptor tsa α adrenergic, dopamine receptors, le M1 le M2 receptors.Har'a bona, litla-morao tsa tsamaiso ea methapo ea bohareng ke tse fokolang, ke moloko o mocha oa lithethefatsi tsa antiallergic tse khethiloeng.Olopatadine ke mohanyetsi ea matla, ea khethiloeng oa H1 histamine receptor (Ki = 16-41.1 nM), e nang le likamano tse tlaase haholo bakeng sa li-receptor tsa H2 le H3 (Ki = 43.4 le 172 μM, ka ho latellana).E thibela phetolo ea phosphoinositide e bakoang ke histamine liseleng tse ka thōko (IC50 = 9.5-39.9 nM) 'me e thibela ho se sebetse ha cutaneous anaphylaxis ho likhoto (ED50 = 49 μg / kg) le anaphylactic bronchoconstriction likolobeng tsa Guinea (ID50 = 30 μg / kg).Olopatadine e sebetsa hantle ho phekola allergic rhinitis le conjunctivitis.E boetse e hatella ho hlohlona ho bakuli ba nang le urticaria e sa foleng e laoloang hantle.Ho batho, antihistamine ena ha e bake ho senyeha ha kelello kapa psychomotor ho litekanyetso tsa kalafo.
