Palbociclib CAS 571190-30-2 Purity >99.5% (HPLC) API Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Palbociclib

CAS: 571190-30-2

Bohloeki: >99.5% (HPLC)

Ponahalo: Phofo e tšoeu kapa e sa bosoeu

API Kalafong ea Kankere ea Matsoele

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Palbociclib
Litlhaloso tse tšoanang	PD-0332991;Otava-Bb 1115529;Ibrance
Nomoro ea CAS	571190-30-2
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C24H29N7O2
Boima ba Molek'hule	447.54
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e tšoeu kapa e sa bosoeu
1H NMR Spectrum	E Lumellanang le Sebopeho
HPLC	E Lumellanang le Sebopeho
Lintho Tse Amanang
Tšilafalo ea Motho ka Mong	<0.50%
Litšila ka Kakaretso	<1.00%
Tahlehelo ka ho Omisa	<0.50%
Masalla a ho Ignition	<0.10%
Litšepe tse boima	<10ppm
Mokhoa oa Bohloeki / Analysis	>99.5% (HPLC)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	API, Phekolong ea Kankere ea Matsoele

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

Palbociclib (CAS: 571190-30-2) ke inhibitor e fumanehang ka molomo ea cyclin-dependent kinase (CDK) e nang le ts'ebetso e ka bang teng ea antineoplastic.Palbociclib e thibela ka mokhoa o ikhethileng cyclin-dependent kinase 4 (CDK4) le 6 (CDK6), ka tsela eo e thibela retinoblastoma (Rb) protheine phosphorylation qalong ea mohato oa G1 o lebisang ho ts'oaroeng ha lisele tsa lisele.Sena se hatella ho ikatisa ha DNA mme se fokotsa ho ata ha lisele tsa tumor.Palbociclib ke moemeli oa pele oa sehlopha se secha sa lithethefatsi sa cyclin-dependent kinase inhibitors.Phello ena e fokotsa ho ata ha lisele (ho hōla ha lisele le ho arohana).E sebelisoa e le moemeli oa antineoplastic ho kankere ea matsoele e tsoetseng pele kapa ea metastatic.