Palbociclib Intermediate CAS 1016636-76-2 Bohloeki >99.0% (HPLC) Factory

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: 6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one

CAS: 1016636-76-2

Bohloeki: >99.0% (HPLC)

Ponahalo: Phofo e Bosoeu ho ea ho Bosehla bo Khanyang

Bohareng ba Palbociclib (CAS: 571190-30-2)

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one
Litlhaloso tse tšoanang	Palbociclib-Pb3
Nomoro ea CAS	1016636-76-2
Nomoro ea KAtse	RF-PI1849
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C13H13BrClN3O
Boima ba Molek'hule	342.63
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Bosoeu ho isa ho e Khanyang
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Lintho Tse Amanang	<1.00%
Tahlehelo ka ho Omisa	<0.50%
Metsi (KF)	<0.50%
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Palbociclib (CAS: 571190-30-2)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7 (8H)-one (CAS: 1016636-76-2) ke karolo e bohareng ea Palbociclib (CAS: 571190- 30-2).Palbociclib ke setlhare sa kalafo ea mofetše oa matsoele oa ER-positive le HER2-negative o hlahisitsoeng.Palbociclib ke inhibitor e khethang ea CDK4 le CDK6 e itšetlehileng ka li-cyclin.Ka la 3 Hlakola, 2015, US FDA e amohetse Pfizer's Palbociclib (lebitso la khoebo: Ibrance) bakeng sa kalafo ea mofetše oa matsoele o tsoetseng pele / oa metastatic ho basali ba postmenopausal.Palbociclib ke inhibitor ea pele ea CDK4/6 ho fumana tumello ea FDA.