Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Factory

Tlhaloso e Khutšoanyane:

Lebitso: Paroxetine Hydrochloride Hemihydrate

CAS: 110429-35-1

Assay (Sesebediswa sa Anhydrous): 97.5~102.0%

Ponahalo: Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu

API Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale Paroxetine Hydrochloride Hemihydrate
Litlhaloso tse tšoanang (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl] -4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl
Nomoro ea CAS 110429-35-1
Nomoro ea KAtse RF-PI1946
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C19H20FNO3·HCl·1/2H2O
Boima ba Molek'hule 374.84
Melting Point 140.0 ~ 143.0℃
Potoloho e Khethehileng [α]20/D -88.0° ho ya ho -92.0° (C=1, MeOH, Calcd.on anh.substance)
Solubility Hoo e ka bang ha e qhibilihe ka metsing;Ho qhibiliha haholo ho Dimethylformamide, Methanol;E qhibiliha ka Ethanol
Brand Ruifu Chemical

Litlhaloso:

Litaba Litlhaloso Liphetho
Ponahalo
Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu Ikamahanye
Boitsebiso A
Maqhubu a ho monya a infrared a lokela ho lumellana le spectrum ea litšupiso Ikamahanye
Boitsebiso B Sebaka se seholo sa tlhōrō le nako ea ho boloka tharollo ea teko e lokela ho lumellana le tharollo ea litšupiso Ikamahanye
Boitsebiso C Metsi (ka KF) Ikamahanye
Boitsebiso D Karabelo ea chloride Ikamahanye
Tšilafalo D
≤0.20% Absent
Tšilafalo G ≤0.001%  
Lintho Tse Amanang
Tšilafalo A: ≤0.30% 0.03%
Litšila tse sa Boleloeng: Bakeng sa litšila tsohle, ≤0.10% 0.06%
Kakaretso ea Litšila: ≤0.50% 0.10%
Litšepe tse boima ≤0.002% <0.002%
Metsi (ka KF) 2.20%~2.70% 2.46%
Molora o Sulfated ≤0.10% <0.10%
Tlhahlobo 97.5%~102.0% (Sesebediswa se senang metsi) 100.2%
Metsoako e setseng
Methanol ≤0.30% 0.001%
Acetone ≤0.50% 0.001%
Isopropanol ≤0.50% 0.04%
Dichloromethane ≤0.06% Ha ho letho
Toluene ≤0.089% 0.003%
Qetello: Ho lumellana le EP7.0.

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

1

LBH:

Kopo:

Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) ke e 'ngoe ea tse matla ka ho fetisisa le tse khethiloeng tsa serotonin reuptake inhibitors (SSRI);sethibela maikutlo.Ke phenylpiperidine derivative, e matla haholo ebile e khetha ST (serotonin transporter/5-HT) uptake inhibitor.E sebetsa ka ho tlama ho ST (serotonin transporter / SERT) e nang le kamano e phahameng (Ki = 05 nM).Antidepressant le anxiolytic in vivo.Paroxetine hydrochloride e ka sebelisoa ho phekola khatello ea maikutlo, e leng sethethefatsi se secha se thibelang khatello ea maikutlo.E ka boela ea sebelisoa ho alafa lefu la ho tšoha, lefu la ho tšoenyeha ka kakaretso, lefu la ho tšoenyeha ha sechaba, lefu la ho hlobaela (OCD), ho hlobaela, lefu la premenstrual, ho tsoa pele ho nako le mafu a mang, ka phello e ntle ea pholiso le litlamorao tse fokolang.Phekola mefuta eohle ea khatello ea maikutlo.Ho kenyelletsa ho tepella maikutlo ka ho tšoenyeha le ho tepella maikutlong.Matšoao a tloaelehileng a ho tepella maikutlong: mokhathala, mathata a ho robala, ho hloka thahasello le ho thabela mesebetsi ea letsatsi le letsatsi, ho lahleheloa ke takatso ea lijo.Ka mor'a hore phello ea phekolo e khotsofatsoe, e ka thibela ho khutla ha khatello ea maikutlo.

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