Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Factory
Ruifu Chemical Supply Ka Bohloeki bo Phahameng
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
Lebitso la Lik'hemik'hale | Paroxetine Hydrochloride Hemihydrate |
Litlhaloso tse tšoanang | (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl] -4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
Nomoro ea CAS | 110429-35-1 |
Nomoro ea KAtse | RF-PI1946 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C19H20FNO3·HCl·1/2H2O |
Boima ba Molek'hule | 374.84 |
Melting Point | 140.0 ~ 143.0℃ |
Potoloho e Khethehileng [α]20/D | -88.0° ho ya ho -92.0° (C=1, MeOH, Calcd.on anh.substance) |
Solubility | Hoo e ka bang ha e qhibilihe ka metsing;Ho qhibiliha haholo ho Dimethylformamide, Methanol;E qhibiliha ka Ethanol |
Brand | Ruifu Chemical |
Litaba | Litlhaloso | Liphetho |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu | Ikamahanye |
Boitsebiso A | Maqhubu a ho monya a infrared a lokela ho lumellana le spectrum ea litšupiso | Ikamahanye |
Boitsebiso B | Sebaka se seholo sa tlhōrō le nako ea ho boloka tharollo ea teko e lokela ho lumellana le tharollo ea litšupiso | Ikamahanye |
Boitsebiso C | Metsi (ka KF) | Ikamahanye |
Boitsebiso D | Karabelo ea chloride | Ikamahanye |
Tšilafalo D | ≤0.20% | Absent |
Tšilafalo G | ≤0.001% | |
Lintho Tse Amanang | Tšilafalo A: ≤0.30% | 0.03% |
Litšila tse sa Boleloeng: Bakeng sa litšila tsohle, ≤0.10% | 0.06% | |
Kakaretso ea Litšila: ≤0.50% | 0.10% | |
Litšepe tse boima | ≤0.002% | <0.002% |
Metsi (ka KF) | 2.20%~2.70% | 2.46% |
Molora o Sulfated | ≤0.10% | <0.10% |
Tlhahlobo | 97.5%~102.0% (Sesebediswa se senang metsi) | 100.2% |
Metsoako e setseng | ||
Methanol | ≤0.30% | 0.001% |
Acetone | ≤0.50% | 0.001% |
Isopropanol | ≤0.50% | 0.04% |
Dichloromethane | ≤0.06% | Ha ho letho |
Toluene | ≤0.089% | 0.003% |
Qetello: Ho lumellana le EP7.0. |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) ke e 'ngoe ea tse matla ka ho fetisisa le tse khethiloeng tsa serotonin reuptake inhibitors (SSRI);sethibela maikutlo.Ke phenylpiperidine derivative, e matla haholo ebile e khetha ST (serotonin transporter/5-HT) uptake inhibitor.E sebetsa ka ho tlama ho ST (serotonin transporter / SERT) e nang le kamano e phahameng (Ki = 05 nM).Antidepressant le anxiolytic in vivo.Paroxetine hydrochloride e ka sebelisoa ho phekola khatello ea maikutlo, e leng sethethefatsi se secha se thibelang khatello ea maikutlo.E ka boela ea sebelisoa ho alafa lefu la ho tšoha, lefu la ho tšoenyeha ka kakaretso, lefu la ho tšoenyeha ha sechaba, lefu la ho hlobaela (OCD), ho hlobaela, lefu la premenstrual, ho tsoa pele ho nako le mafu a mang, ka phello e ntle ea pholiso le litlamorao tse fokolang.Phekola mefuta eohle ea khatello ea maikutlo.Ho kenyelletsa ho tepella maikutlo ka ho tšoenyeha le ho tepella maikutlong.Matšoao a tloaelehileng a ho tepella maikutlong: mokhathala, mathata a ho robala, ho hloka thahasello le ho thabela mesebetsi ea letsatsi le letsatsi, ho lahleheloa ke takatso ea lijo.Ka mor'a hore phello ea phekolo e khotsofatsoe, e ka thibela ho khutla ha khatello ea maikutlo.