Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Intermediate High Quality
Phepelo ea Feme e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Posaconazole Related Intermediates Commercial Production
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Lebitso la Lik'hemik'hale | Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate |
Litlhaloso tse tšoanang | Posaconazole ea Mahareng |
Nomoro ea CAS | 184177-81-9 |
Nomoro ea KAtse | RF-PI290 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C23H23N3O3 |
Boima ba Molek'hule | 389.45 |
Botenya | 1.296 |
Boemo ba ho Romela | Tlas'a Mocheso oa Ambient |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Pale Brown ho Grey Powder |
Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšepe tse boima | ≤20ppm |
Tšilafalo e le Mong | ≤0.50% |
Litšila ka Kakaretso | ≤1.0% |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Bohareng ba Posaconazole (CAS 171228-49-2) |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate (CAS 184177-81-9) ke Bohareng ba Posaconazole (CAS 171228-49-2).Posaconazole ke motsoako o pharaletseng, moloko oa bobeli, motsoako oa triazole o nang le ts'ebetso ea antifungal.E amohetsoe bakeng sa tšebeliso ea bongaka United States ka Loetse 2006, 'me e fumaneha joalo ka meriana e akaretsang.Posaconazole ke triazole antifungal lithethefatsi tse rekisoang United States ke Schering-Plough tlas'a lebitso la khoebo la Noxafil.Posaconazole e sebetsa ka ho sitisa ho paka haufi-ufi ha liketane tsa acyl tsa phospholipids, ho sitisa ts'ebetso ea litsamaiso tse itseng tsa enzyme tse kentsoeng lera tse kang ATPase le li-enzyme tsa sistimi ea lipalangoang tsa elektronike, ka hona, li thibela kholo ea li-fungus.E etsa sena ka ho thibela tlhahiso ea ergosterol ka ho thibela enzyme lanosterol 14a-demethylase le ho bokella li-precursors tsa methylated sterol.