Pirfenidone CAS 53179-13-8 Bohloeki ≥99.0% IPF
Fana ka Bohloeki bo Phahameng, Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: Pirfenidone
CAS: 53179-13-8
| Lebitso la Lik'hemik'hale | Pirfenidone |
| Litlhaloso tse tšoanang | Perfenidone;5-Methyl-1-Phenylpyridine-2 (1H) -e le 'ngoe;PFD;S-7701;AMR-69 |
| Nomoro ea CAS | 53179-13-8 |
| Nomoro ea KAtse | RF-API108 |
| Boemo ba Setoko | E teng thepeng e teng ka lebenkeleng |
| Foromo ea limolek'hule | C12H11NO |
| Boima ba Molek'hule | 185.22 |
| Melting Point | 96.0 ho isa ho 97.0 ℃ |
| Solubility | E qhibiliha ka DMSO |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e Bosoeu ho ea ho Khanyang |
| Boitsebiso | IR |
| Bohloeki | ≥99.0% |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Molora o Sulfated | ≤0.20% |
| Tšilafalo e le Mong | ≤0.50% |
| Litšila ka Kakaretso | ≤1.0% |
| Litšepe tse boima | ≤20ppm |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API, Idiopathic Pulmonary Fibrosis (IPF) |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Pirfenidone (CAS: 53179-13-8) e sehlopheng sa meriana e bitsoang li-antifibrotic agents.Pirfenidone e bontšitse ts'ebetso maemong a mangata a fibrotic, ho kenyelletsa le a matšoafo, liphio le sebete.E ama sesole sa 'mele oa hau mme e fokotsa bongata ba fibrosis (maqeba) matšoafong.Pirfenidone ke o mong oa meriana e 'meli e amohetsoeng Canada ho phekola Idiopathic Pulmonary Fibrosis (IPF).Pirfenidone ke inhibitor bakeng sa tlhahiso ea TGF-β le tlhahiso ea TGF-β e tsosolositsoeng ea collagen, e fokotsa tlhahiso ea TNF-α le IL-1β, hape e na le li-anti-fibrotic le anti-inflammatory properties.E ile ea amoheloa ka lekhetlo la pele Japane bakeng sa phekolo ea bakuli ba idiopathic pulmonary fibrosis ka mor'a liteko tsa meriana, tlas'a lebitso la khoebo la Pirespa ka Shionogi, ka 2008. E ile ea amoheloa hore e sebelisoe European Union ka 2011, Canada ka 2012, le ka United States ka October 2014.
