Posaconazole CAS 171228-49-2 API Factory Triazole Antifungal Agent High Quality
Phepelo ea Feme ea Posaconazole e Amanang le Li-Intermediate, Tlhahiso ea Khoebo
Posaconazole CAS 171228-49-2
Posaconazole Mahareng POA CAS 149809-43-8
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2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Lebitso la Lik'hemik'hale | Posaconazole |
Litlhaloso tse tšoanang | POS;SCH 56592;4 -- [4--[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl] methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one |
Nomoro ea CAS | 171228-49-2 |
Nomoro ea KAtse | RF-API77 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C37H42F2N8O4 |
Boima ba Molek'hule | 700.78 |
Botenya | 1.36 g/cm3 |
Solubility | E qhibilihang ka har'a DMSO, ha e qhibilihe ka metsing |
Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Boitsebiso A | IR: Maqhubu a ho monya ha infrared a sehlahisoa a lokela ho lumellana le a ntho ea litšupiso. |
Boitsebiso B | HPLC Nako ea ho boloka e tšoana le ntho ea litšupiso |
Melting Point | 167.0 ~ 171.0℃ |
Phetoho e khethehileng [a]20 | -24.0° ~ -28.0° (C=1, CHCL3) |
Metsi (KF) | ≤1.0% |
Masalla a ho Ignition | ≤0.10% |
Lintho Tse Amanang | |
HT 909-24 | ≤0.20% |
Tšilafalo efe kapa efe ea Motho ka Mong | ≤0.10% |
Litšila ka Kakaretso | ≤1.0% |
Metsoako e setseng | |
Methanol | ≤3000ppm |
Methyl tert-Butyl Ether | ≤5000ppm |
Isopropanol | ≤5000ppm |
Dimethyl Sulfoxide | ≤5000ppm |
Dichloromethane | ≤600ppm |
Tlhahlobo | 98.0% ~ 102.0% (E baloa ka mokhoa o omisitsoeng) |
Litšepe tse boima | ≤10ppm |
Isomer | Enantiomer ≤0.10% |
Tšilafalo efe kapa efe ea Motho ≤0.10% | |
Kakaretso ea Litšila ≤1.0% | |
Tekanyetso ea Teko | Maemo a Khoebo;USP;BP;EP Standard |
Tšebeliso | API, Triazole Antifungal Agent |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Posaconazole (CAS 171228-49-2), ke moloko o pharaletseng, moloko oa bobeli, motsoako oa triazole o nang le ts'ebetso ea antifungal, e qalileng UK, ke setho se secha ka ho fetisisa sa sehlopha sa azole sa li-antifungal agents ho fihla 'marakeng.E bontšoa bakeng sa ho phekola le ho thibela mafu a mangata a fungal, ho akarelletsa le aspergillosis, fusariosis, chromoblastomycosis, mycetoma, le coccidiomycosis ho bakuli ba hanyetsang, kapa ba sa mamelle, phekolo e tloaelehileng ea amphotericin B le/kapa itraconazole.Naheng ea Amerika, e amohetsoe bakeng sa prophylaxis ea ts'oaetso ea Aspergillus le Candida ho bakuli ba lilemo tse 13 ba kotsing e kholo ea ho tšoaroa ke ts'oaetso ena ka lebaka la ho fokola haholo.Ho phaella moo, e lumelloa bakeng sa phekolo ea oropharyngeal candidiasis.Posaconazole e na le ts'ebetso e atolositsoeng ho feta litho tse ling tsa li-azole antifungals.Ntle le ts'ebetso e matla khahlanong le linyeoe tsa refractory tsa aspergillosis le fluconazole-resistant Candida, e bonts'a ts'ebetso khahlanong le Zygomycetes.Posaconazole ke triazole antifungal lithethefatsi tse rekisoang United States ke Schering-Plough tlas'a lebitso la khoebo la Noxafil.