Potassium Bis(trimethylsilyl)amide CAS 40949-94-8 (0.5M Tharollo ka Toluene)
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Lebitso la Lik'hemik'hale | Potassium Bis(trimethylsilyl)amide |
Litlhaloso tse tšoanang | Hexamethyldisilazane Potassium Letsoai;Potassium Hexamethyldisilazane;KHMDS |
Nomoro ea CAS | 40949-94-8 |
Nomoro ea KAtse | RF-PI2227 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C6H18KNSi2 |
Boima ba Molek'hule | 199.49 |
Ntlha e belang | 111℃ |
Botenya | 0.877 g/mL ho 25℃ |
Sehlopha sa Likotsi | 3 (8);Mokelikeli o tukang, o senyang |
Sehlopha sa ho paka | II |
Solubility | E kopane le Terahydrofuran, Ether, Benzene le Toluene |
Ho qhibiliha ha Metsi | E arabelana le Metsi |
Hydrolytic Sensitivity | 8: E arabela ka Potlako ka Mongobo, Metsi, Litlhapi tsa pProtic |
Botsitso | E Mamela Mongobo, Ha e Mamelle Moeeng, E Mamela Mocheso.Boloka Tlas'a Nitrojene.E ka Etsa Moputso.Thempereichara e Ambient. |
Polokeho | Kotsi - Tefiso e Ekelitsoeng ea Thepa e Kotsi e ka 'na ea sebetsa |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Yellow to Brown Liquid |
Litšila tse ling | ≤3.00% |
Litaba tsa Active Base | 0.45~0,55 M |
Tekanyetso ea Teko | Maemo a Khoebo |
Sephutheloana:Botlolo, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:E na le kutloelo-bohloko ho mongobo le moea.Boloka sebakeng se phodileng.Boloka setshelo se koetsoe ka thata sebakeng se omeletseng le se nang le moea o motle.Lijana tse butsoeng li tlameha ho koaloa hape ka hloko le ho bolokoa li otlolohile ho thibela ho lutla.Tšoara 'me u boloke tlas'a khase e sa sebetseng.Ha e lumellane le lisebelisoa tse matla tsa oxidizing.
Lipolelo tsa Kotsi:Mokelikeli o tukang haholo le mouoane.E baka cheso e matla ea letlalo le tšenyo ea mahlo.E baka tšenyo e kholo ea mahlo.Ho belaelloang ka ho senya thari kapa ngoana ea so hlaha.E ka baka tšenyo lithong tsa 'mele ka ho pepesehela nako e telele kapa khafetsa.E ka baka ho otsela kapa ho tsekela.
Potassium Bis(trimethylsilyl)amide (0.5M Tharollo ka Toluene) (e atisang ho khutsufatsoa e le KHMDS) (CAS: 40949-94-8) ke setsi se matla, se seng sa nucleophilic se nang le pKa e ka bang 26 (bapisa le lithium diisopropylamide, ho 36 ).E fumaneha khoebong e le e tiileng le e le tharollo mefuteng e fapaneng ea lihlapolli (mohlala. THF, 2Me-THF, toluene, le MTBE).Li-reagents tse tšoanang li kenyelletsa lithium bis(trimethylsilyl)amide (LiHMDS) le sodium bis(trimethylsilyl)amide (NaHMDS).Non-nucleophilic megasteric strong base.Li-intermediates tsa meriana, tse sebelisoang ho hlahisa li-cephalosporins tsa maiketsetso.KHMDSke sesebelisoa sa lik'hemik'hale se sebelisoang ho chromatography ea metsi e sebetsang hantle haholo.E sebelisetsoa ho etsa li-complexes tse tsitsitseng tse nang le potasiamo, tse ntan'o aroloa ke kholomo.KHMDS e boetse e sebelisoa liphuputsong tsa biochemical le joalo ka asymmetric synthesis catalyst.KHMDS ke setsi se matla se sebelisoang metsoakong ea alkylation carbonyl.KHMDS e sebelisoa ha ho etsoa 5-Azacytidine, sethethefatsi sa antineoplastic.E boetse e sebelisoa ha ho lokisoa li-agonists tsa β3-AR tse sebelisoang ho li-anti-stress formulations.E boetse e sebelisoa e le reagent ha ho etsoa li-complexes tsa lanthanide tse sebelisoang liketsong tse khethiloeng tsa cyclization.