Pregabalin CAS 148553-50-8 Purity >99.0% (HPLC) Antiepileptic API

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Pregabalin

CAS: 148553-50-8

Ponahalo: Bosoeu ho isa ho Bosoeu ba Crystalline Powder

Bohloeki:> 99.0% (HPLC ka motheo o omisitsoeng)

Meriana ea Moloko oa Bobeli ea Antiepileptic (AED)

API Boleng bo Phahameng, Tlhahiso ea Khoebo

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Moetsi ea nang le Bohloeki bo Phahameng le Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: PregabalinCAS: 148553-50-8
Pregabalin ke moriana oa antiepileptic oa moloko oa bobeli (AED)

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Pregabalin
Litlhaloso tse tšoanang	(S) -3-(Aminomethyl) -5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Lyrica
Nomoro ea CAS	148553-50-8
Nomoro ea KAtse	RF-API57
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C8H17NO2
Boima ba Molek'hule	159.23
Melting Point	194.0 ~ 196.0 ℃
Sollubility ka Metsing	Ha e Monyehe ka Metsing
Solubility	Ha Hanyane Hanyenyane ka Ethanol
Boemo ba ho Romela	Tlas'a Mocheso oa Ambient
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo ea Crystalline e tšoeu ho isa ho e tšoeu
Boitsebiso	IR: E Tšoanang le Tšebeliso ea Lintho
Phetoho e khethehileng	+10.0°~+13.0° (C=1, Metsi)
Tahlehelo ka ho Omisa	<0.50%
Molora oa Sulfate	<0.10%
Lintho Tse Amanang	Tšilafalo A <0.15%
	Litšila tse sa Boleloeng tse Hlahang Pele ho Pregabalin (teko ea A) <0.10%
	Litšila tse sa Boleloeng tse Eluting Ka mor'a Pregabalin (teko ea B) <0.10%
	Kakaretso ea teko A le B <0.50%
Bohloeki Ka HPLC R-Isomer	<0.15%
Heavy Metals (as Pb)	<10ppm
Chlorides (Cl)	<0.05%
Metsoako e setseng
Joala ba Isopropyl	<5000ppm
Ethyl Acetate	<5000ppm
Tetrahydrofuran	<250ppm
Ether ea isopropyl	<500ppm
Ethanol	<1000ppm
Mokhoa oa Bohloeki / Analysis	> 99.0% (HPLC ka motheo o omisitsoeng)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Antiepileptic Drug API

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

Pregabalin ke moloko oa bobeli oa lithethefatsi tsa antiepileptic (AED) tse tsejoang ka lebitso la lebitso la Lyrica (Pfizer, Tadworth) UK le USA, e nang le sebopeho sa γ-amino butyric acid sebopeho sa eona sa molek'hule, se nang le litlamorao tsa anticonvulsant. e atlehile ho ntlafatsoa ke k'hamphani ea Pfizer bakeng sa kalafo ea bohloko ba peripheral neuropathic, kapa kalafo ea adjuvant ea ho ts'oaroa ha karolo e itseng.Pregabalin ke sethethefatsi sa Anticonvulsant le antiepileptic se sebelisetsoang ho phekola lefu la sethoathoa, bohloko ba neuropathic, fibromyalgia, le lefu la ho tšoenyeha ka kakaretso.Tšebeliso ea eona bakeng sa lefu la sethoathoa ke phekolo ea tlatsetso bakeng sa ho tsietsana ka mokhoa o sa fellang kapa ntle le kakaretso ea bobeli ho batho ba baholo.Ka December 2008, US Food and Drug Administration (FDA) e ile ea amohela pregabalin (lebitso la khoebo "Lyrica") bakeng sa phekolo ea lefu la tsoekere la peripheral neuropathic pain (DPN) le postherpetic neuralgia (PHN) e leng Bobeli bohloko bo tloaelehileng ba neuropathic.Pregabalin e na le sesupo se lumelletsoeng mme e sebelisoa haholo bakeng sa kalafo ea lefu la ho tšoenyeha le akaretsang.Liteko tse 'maloa tse sa sebetseng, tse foufetseng habeli, tse laoloang ke placebo li fumane hore pregabalin ke phekolo e sebetsang bakeng sa bakuli ba nang le bothata ba ho tšoenyeha ka kakaretso le lefu la ho tšoenyeha ha sechaba.Lethal dose ea titration Phekolo ea lefu la sethoathoa: 25 mg bd ka matsatsi a 7, e eketsoe ka 50 mg ka matsatsi a 7;tlhokomelo e tloaelehileng 300 mg letsatsi le letsatsi, e arotsoe ka litekanyetso tse 2 kapa tse 3 (max. 600 mg ka letsatsi, e arotsoe ka litekanyetso tse 2 kapa tse 3).Matšoenyeho a tloaelehileng a ho tšoenyeha: 150 mg letsatsi le leng le le leng, e arotsoe ka litekanyetso tsa 2 kapa 3, bakeng sa matsatsi a 7, ho eketsoa ka 150 mg ka matsatsi a 7 (max. 600 mg letsatsi le letsatsi, e arotsoe ka litekanyetso tsa 2 kapa 3).Haeba u emisa pregabalin, ho kgothaletswa ho theola bonyane beke e le 'ngoe ho qoba ho tsoa ka tšohanyetso.Tlhokomeliso Bakuli ba nang le maemo a ka bakang lefu la encephalopathy.Bakuli ba nang le ts'ebetso e matla ea pelo ea congestive.