Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Phepelo ea Vonoprazan Fumarate le ea Mahareng e Amanang
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Lebitso la Lik'hemik'hale | Pyridine-3-Sulfonyl Chloride |
| Litlhaloso tse tšoanang | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
| Nomoro ea CAS | 16133-25-8 |
| Nomoro ea KAtse | RF-PI540 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C5H4ClNO2S |
| Boima ba Molek'hule | 177.61 |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Mokelikeli o se nang 'Mala kapa o Bosehla bo Bosehla |
| Mokhoa oa Bohloeki / Analysis | ≥98.5% (GC) |
| Ntlha e belang | 110.0 ~ 112.0℃/2mm Hg |
| Tšilafalo e le Mong | ≤0.50% |
| Litšila ka Kakaretso | ≤1.5% |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Bohareng ba Vonoprazan Fumarate (CAS: 1260141-27-2) |
Sephutheloana: Botlolo, 25kg / Barrel, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) ke bohareng ba Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, e fumanoeng le ho ntlafatsoa ke Takeda le Otsuka, e amohetsoe ke PMDA ea Japane ka December 2014, 'me e bontšoa bakeng sa phekolo ea seso sa ka mpeng, seso sa duodenal le reflux esophagitis.Vonoprazan fumarate e na le mokhoa o mocha oa ts'ebetso o bitsoang li-blocker tsa potassium-competitive acid, tse thibelang ka tlholisano ho tlama li-ion tsa potasiamo ho H+, K+ -ATPase (eo hape e tsejoang e le pompo ea proton) mohatong oa ho qetela oa secretion ea asiti ea gastric ka har'a lisele tsa parietal tsa gastric.Vonoprazan ha e thibele mosebetsi oa Na +, K + -ATPase esita le ka makhetlo a 500 a phahameng ho feta a litekanyetso tsa bona tsa IC50 khahlanong le mosebetsi oa gastric H +, K + -ATPase.Ho feta moo, sethethefatsi ha se amehe ke boemo ba lekunutu ba gastric, ho fapana le li-PPI.
