(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0~102.0% (HPLC) Factory
Ruifu Chemical Supply Lansoprazole Intermediates
Lansoprazole CAS 103577-45-3
Lansoprazole Chloride Compound CAS 127337-60-4
(R)-Lansoprazole Dexlansoprazole CAS 138530-94-6
Lebitso la Lik'hemik'hale | (R) - Lansoprazole |
Litlhaloso tse tšoanang | R-(+)-Lansoprazole;Dexlansoprazole;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl] -1H-benzimidazole;T 168390;TAK 390;Tšilafalo ea Lansoprazole 14;Litšila tse Amanang le Dexlansoprazole 2;(R) -2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl] -1H-Benzimidazole; |
Nomoro ea CAS | 138530-94-6 |
Nomoro ea KAtse | RF-PI1916 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | Setšoantšo sa C16H14F3N3O2S |
Boima ba Molek'hule | 369.36 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Solubility | E qhibiliha ka har'a Dimethylformamide, e batla e sa qhibilihe ka metsing |
Ho hlaka le Mmala oa Tharollo | E Kopana le Tlhokahalo |
Boitsebiso ba IR | Maqhubu a ho monya a infrared a lokela ho lumellana le ntho ea litšupiso |
Boitsebiso ba HPLC | Nako ea ho boloka tlhōrō e kholo e lokela ho lumellana le ea referense |
Phetoho e khethehileng | +142.0°~+149.0° |
Melting Point | ~140.0℃ |
Litaba tsa Metsi (KF) | <1.00% |
Masalla a ho Ignition | <0.10% |
Litšila Tse Amanang | (HPLC) |
Li-oxide tsa naetrojene | <0.10% |
Sulfone | <0.40% |
Sulfidi | <0.20% |
Tšilafalo efe kapa efe e 'Ngoe | <0.10% |
Litšila ka Kakaretso | <0.60% |
Optical Purity (HPLC) | >99.5% |
Tlhahlobo | 98.0~102.0% (HPLC, %w/w, motheong oa anhydrous, ha e na solvent) |
Litšepe tse boima | <10ppm |
Metsoako e setseng | |
Toluene | <890ppm |
n-Heptane | <5000ppm |
Endotoxin ea baktheria | <2.5EU/mg |
Tekanyetso ea Teko | USP Standard;Pharmacopoeia ea China |
Tšebeliso | API;Proton Pump Inhibitor e sebetsang ka molomo |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
(R) -Lansoprazole (CAS: 138530-94-6) ke R enantiomer ea Lansoprazole, Lansoprazole (AG 1749) ke proton pump inhibitor e sebetsang ka molomo e thibelang mpa ho hlahisa acid.Dexlansoprazole bakeng sa Lansoprazole dextroisomer, ke mofuta oa lithethefatsi tse khahlanong le peptic ulcer bakeng sa derivatives ea benzimidazole e nkeloang sebaka, ka sebopeho sa molek'hule ho element fluorine, ea bobeli ea proton pump inhibitors omeprazole kamora moo.Dexlansoprazole e na le phello ea ho thibela secretion ea gastric acid, phello e molemo ho feta ea lithethefatsi tse ling (Omeprazole, Pantoprazole, Rebela, Tetrazolium) e ka thibela haholo ho hlaha ha seso.E phahametse famotidine kapa Omeprazole bakeng sa tšenyo ea mucosa ea ka mpeng e bakoang ke joala le seso sa duodenal haholo-holo se bakoang ke acid hypersecretion.Ho phaella moo, sehlahisoa se na le phello e tšoanang ea anti Helicobacter pylori joaloka ho lokisetsa bismuth, 'me e sebelisetsoa reflux esophagitis le Zhuo AI syndrome.Takeda Pharmaceuticals e amohetse tumello ea dexlansoprazole, e leng motsoako o habeli oa (R) -isomer ea lansoprazol proton pump inhibitor (PPI) e seng e ntse e le 'marakeng, ho tsoa ho FDA ka Pherekhong 2009. Dexlansoprazole ke capsule e liehang ea ho lokolloa bakeng sa kalafo ea molomo hang ka letsatsi. ea ho nyeheloa ke pelo e amanang le matšoao a non-erosive gastroesophageal reflux disease (GERD), pholiso ea erosive esophagitis (EE) le tlhokomelo ea EE e folisitsoeng.